Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents

HPLC-MS/MS-Mediated Analysis of the Pharmacokinetics, Bioavailability, and Tissue Distribution of Schisandrol B in Rats

(2021) Dahu Liang et al.   International Journal of Analytical Chemistry

Effects of Shengmai San on key enzymes involved in hepatic and intestinal drug metabolism in rats

(2021) Tzu-Yi Chiang et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Comprehensive Review on Schisandrin B and Its Biological Properties

(2020) M. I. Nasser et al.   Oxidative Medicine and Cellular Longevity

Schisandra Extract and Ascorbic Acid Synergistically Enhance Cognition in Mice through Modulation of Mitochondrial Respiration

(2020) Yunseon Jang et al.   Nutrients

Gomisin J inhibits the glioma progression by inducing apoptosis and reducing HKII-regulated glycolysis

(2020) Ruilong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives

(2019) Adriana Nowak et al.   Nutrients

Mitochondria as playmakers of apoptosis, autophagy and senescence

(2019) Marianna Abate et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Schisandrin B alleviates acute oxidative stress via modulating Nrf2/Keap1-mediated antioxidant pathway

(2018) Wu Ying et al.   Applied Physiology Nutrition and Metabolism

Schisandrin A prevents oxidative stress-induced DNA damage and apoptosis by attenuating ROS generation in C2C12 cells

(2018) Yung Hyun Choi   BIOMEDICINE & PHARMACOTHERAPY

Schisanhenol improves learning and memory in scopolamine-treated mice by reducing acetylcholinesterase activity and attenuating oxidative damage through SIRT1-PGC-1α-Tau signaling pathway

(2018) Yunfeng Han et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Pharmacokinetics of Schizandrin and Its Pharmaceutical Products Assessed Using a Validated LC–MS/MS Method

(2018) Chi-Lin Li et al.   MOLECULES

Deoxyschizandrin, Isolated from Schisandra Berries, Induces Cell Cycle Arrest in Ovarian Cancer Cells and Inhibits the Protumoural Activation of Tumour-Associated Macrophages

(2018) Kijun Lee et al.   Nutrients

Schisandrin B protects human keratinocyte-derived HaCaT�cells from tert-butyl hydroperoxide-induced oxidative damage through activating the Nrf2 signaling pathway

(2018) Ming Ding et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Schisandrin B Ameliorates Myocardial Ischemia/Reperfusion Injury Through Attenuation of Endoplasmic Reticulum Stress-Induced Apoptosis

(2017) Wei Zhang et al.   INFLAMMATION

Schisantherin A suppresses interleukin-1β-induced inflammation in human chondrocytes via inhibition of NF-κB and MAPKs activation

(2016) Shiyao Liao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lignans from Schisandra chinensis ameliorate cognition deficits and attenuate brain oxidative damage induced by D-galactose in rats

(2016) Tingxu Yan et al.   METABOLIC BRAIN DISEASE

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies

(2016) Agnieszka Szopa et al.   PHYTOCHEMISTRY REVIEWS

Ameliorative Effects of 5-Hydroxymethyl-2-furfural (5-HMF) from Schisandra chinensis on Alcoholic Liver Oxidative Injury in Mice

(2015) Wei Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of Schisandra chinensis extracts on cough and pulmonary inflammation in a cough hypersensitivity guinea pig model induced by cigarette smoke exposure

(2015) Shan Zhong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Schisandrin C Ameliorates Learning and Memory Deficits by Aβ1-42-induced Oxidative Stress and Neurotoxicity in Mice

(2015) Xin Mao et al.   PHYTOTHERAPY RESEARCH

Schisandrin B Prevents Doxorubicin Induced Cardiac Dysfunction by Modulation of DNA Damage, Oxidative Stress and Inflammation through Inhibition of MAPK/p53 Signaling

(2015) Rajarajan A. Thandavarayan et al.   PLoS One

The Protecting Effect of Deoxyschisandrin and Schisandrin B on HaCaT Cells against UVB-Induced Damage

(2015) Wei Hou et al.   PLoS One

Mitochondrial respiratory chain complexes as sources and targets of thiol-based redox-regulation

(2014) Stefan Dröse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Identification of Key Structural Characteristics of Schisandra chinensis Lignans Involved in P-Glycoprotein Inhibition

(2014) Jiří Slanina et al.   JOURNAL OF NATURAL PRODUCTS

Comparative Studies on Polyphenolic Composition, Antioxidant and Antimicrobial Activities of Schisandra chinensis Leaves and Fruits

(2014) Andrei Mocan et al.   MOLECULES

Dibenzocyclooctadiene lignans from Schisandra chinensis and their inhibitory activity on NO production in lipopolysaccharide-activated microglia cells

(2014) Di Hu et al.   PHYTOCHEMISTRY

Nrf2-Mediated HO-1 Induction Contributes to Antioxidant Capacity of a Schisandrae Fructus Ethanol Extract in C2C12 Myoblasts

(2014) Ji Kang et al.   Nutrients

Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cells

(2013) Matharage Gayani Dilshara et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Gender-dependent pharmacokinetics of lignans in rats after single and multiple oral administration of Schisandra chinensis extract

(2013) Haiyan Xu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pharmacokinetics and tissue distribution study of schisandrin B in rats by ultra-fast liquid chromatography with tandem mass spectrometry

(2013) Heyun Zhu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Protective Effect of Schisandrin B Against Cyclosporine A-Induced Nephrotoxicity In Vitro and In Vivo

(2012) Shaohua Zhu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

In Vitro Cultures of Schisandra chinensis (Turcz.) Baill. (Chinese Magnolia Vine)—a Potential Biotechnological Rich Source of Therapeutically Important Phenolic Acids

(2012) Agnieszka Szopa et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Isolation and physicochemical characterization of polysaccharide fractions isolated from Schisandra chinensis

(2012) Haibin Tong et al.   CHEMISTRY OF NATURAL COMPOUNDS

Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide-induced microglia

(2012) Ke-Wu Zeng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Schisandrin B as a Hormetic Agent for Preventing Age-Related Neurodegenerative Diseases

(2012) Philip Y. Lam et al.   Oxidative Medicine and Cellular Longevity

Deoxyschizandrin Isolated from the Fruits of Schisandra chinensis Ameliorates Aβ1-42-induced Memory Impairment in Mice

(2012) Di Hu et al.   PLANTA MEDICA

In vitro Antioxidation Activity and Genoprotective Effect of Selected Chinese Medicinal Herbs

(2011) Yim Tong Szeto et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Prevention of scopolamine-induced memory deficits by schisandrin B, an antioxidant lignan fromSchisandra chinensisin mice

(2011) Vijayasree V. Giridharan et al.   FREE RADICAL RESEARCH

Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in AML12 hepatocytes

(2011) Pou Kuan Leong et al.   FREE RADICAL RESEARCH

Chemical composition and antioxidant activity of the essential oil ofSchisandra chinensisfruits

(2011) Xiaoqiang Chen et al.   NATURAL PRODUCT RESEARCH

Schisandrin B-Induced Glutathione Antioxidant Response and Cardioprotection Are Mediated by Reactive Oxidant Species Production in Rat Hearts

(2010) Na Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Anti-Inflammatory Effects of Gomisin N, Gomisin J, and Schisandrin C Isolated from the Fruit ofSchisandra chinensis

(2010) Su-Yeon OH et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Isolation of lignans from Schisandra chinensis with anti-proliferative activity in human colorectal carcinoma: Structure–activity relationships

(2010) John Gnabre et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Inhibition of cytochrome P450 3A4 activity by schisandrol A and gomisin A isolated from Fructus Schisandrae chinensis

(2010) C.-K. Wan et al.   PHYTOMEDICINE

Derivatives of schisandrin with increased inhibitory potential on prostaglandin E2 and leukotriene B4 formation in vitro

(2009) Martina Blunder et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Schisantherin A Exhibits Anti-inflammatory Properties by Down-Regulating NF-κB and MAPK Signaling Pathways in Lipopolysaccharide-Treated RAW 264.7 Cells

(2009) Xinxin Ci et al.   INFLAMMATION

Schisandrin B Enhances Cerebral Mitochondrial Antioxidant Status and Structural Integrity, and Protects against Cerebral Ischemia/Reperfusion Injury in Rats

(2008) Na Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Schisandrin B Enhances Renal Mitochondrial Antioxidant Status, Functional and Structural Integrity, and Protects against Gentamicin-Induced Nephrotoxicity in Rats

(2008) Po Yee Chiu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Anti-inflammatory effects of schisandrin isolated from the fruit of Schisandra chinensis Baill

(2008) Lian Yu Guo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of pro-inflammatory responses by lipoxygenases via intracellular reactive oxygen species in vitro and in vivo

(2008) So Yong Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Determination of six lignans in Schisandra chinensis (Turcz.) Baill. Fruits and related Chinese multiherb remedies by HPLC

(2008) Hai Zhang et al.   FOOD CHEMISTRY

Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine

(2008) Alexander Panossian et al.   JOURNAL OF ETHNOPHARMACOLOGY

Schisandrin B stereoisomers protect against hypoxia/reoxygenation-induced apoptosis and inhibit associated changes in Ca2+-induced mitochondrial permeability transition and mitochondrial membrane potential in H9c2 cardiomyocytes

(2008) Po Yee Chiu et al.   LIFE SCIENCES