The COVID-19 Vaccines: Recent Development, Challenges and Prospects

What’s the risk of dying from a fast-spreading COVID-19 variant?

(2021) Smriti Mallapaty   NATURE

Structure-Function Analyses of New SARS-CoV-2 Variants B.1.1.7, B.1.351 and B.1.1.28.1: Clinical, Diagnostic, Therapeutic and Public Health Implications

(2021) Jasdeep Singh et al.   Viruses-Basel

AZD1222 (Covishield) vaccination for COVID-19: Experiences, challenges, and solutions in Nepal

(2021) Ranjit Sah et al.   Travel Medicine and Infectious Disease

The novel Chinese coronavirus (2019‐nCoV) infections: Challenges for fighting the storm

(2020) Matteo Bassetti et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

(2020) Haibo Zhang et al.   INTENSIVE CARE MEDICINE

The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

(2020) Calvin J Gordon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 2019‐new coronavirus epidemic: Evidence for virus evolution

(2020) Domenico Benvenuto et al.   JOURNAL OF MEDICAL VIROLOGY

Understanding of COVID‐19 based on current evidence

(2020) Pengfei Sun et al.   JOURNAL OF MEDICAL VIROLOGY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study

(2020) Joseph T Wu et al.   LANCET

A codon-pair deoptimized live-attenuated vaccine against respiratory syncytial virus is immunogenic and efficacious in non-human primates

(2020) Steffen Mueller et al.   VACCINE

Estimating the Unreported Number of Novel Coronavirus (2019-nCoV) Cases in China in the First Half of January 2020: A Data-Driven Modelling Analysis of the Early Outbreak

(2020) Shi Zhao et al.   Journal of Clinical Medicine

Diagnosing COVID-19: The Disease and Tools for Detection

(2020) Buddhisha Udugama et al.   ACS Nano

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

COVID-19: Gene Transfer to the Rescue?

(2020) Luk H. Vandenberghe   HUMAN GENE THERAPY

SARS-CoV-2 Vaccines: Status Report

(2020) Fatima Amanat et al.   IMMUNITY

Novel coronavirus: From discovery to clinical diagnostics

(2020) Tung Phan   INFECTION GENETICS AND EVOLUTION

Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19)

(2020) Waleed Alhazzani et al.   INTENSIVE CARE MEDICINE

Treatment options for COVID-19: The reality and challenges

(2020) Shio-Shin Jean et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

(2020) Feng-Cai Zhu et al.   LANCET

From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development

(2020) Cuiqing Ma et al.   MICROBES AND INFECTION

Labs rush to study coronavirus in transgenic animals — some are in short supply

(2020) Ewen Callaway   NATURE

Remdesivir for the Treatment of Covid-19 — Preliminary Report

(2020) John H. Beigel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of an inactivated vaccine candidate for SARS-CoV-2

(2020) Qiang Gao et al.   SCIENCE

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2

(2020) Jianzhong Shi et al.   SCIENCE

The First 75 Days of Novel Coronavirus (SARS-CoV-2) Outbreak: Recent Advances, Prevention, and Treatment

(2020) Yuxin Yan et al.   International Journal of Environmental Research and Public Health

Can an effective SARS-CoV-2 vaccine be developed for the older population?

(2020) Graham Pawelec et al.   Immunity & Ageing

Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study

(2020) Qingxian Cai et al.   Engineering

Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes

(2020) Shengli Xia et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

(2020) Pedro M Folegatti et al.   LANCET

SARS-CoV-2 Vaccine Development: Current Status

(2020) Gregory A. Poland et al.   MAYO CLINIC PROCEEDINGS

Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults

(2020) Mark J. Mulligan et al.   NATURE

Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia

(2020) Denis Y Logunov et al.   LANCET

SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

(2020) Gregory A Poland et al.   LANCET

Animal models for COVID-19

(2020) César Muñoz-Fontela et al.   NATURE

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

(2020) Evan J. Anderson et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Review of the Progress and Challenges of Developing a Vaccine for COVID-19

(2020) Omna Sharma et al.   Frontiers in Immunology

Estimation of incubation period distribution of COVID-19 using disease onset forward time: A novel cross-sectional and forward follow-up study

(2020) Jing Qin et al.   Science Advances

Anaphylaxis to the first COVID-19 vaccine: is polyethylene glycol (PEG) the culprit?

(2020) Lene H. Garvey et al.   BRITISH JOURNAL OF ANAESTHESIA

The Current Status of Drug Repositioning and Vaccine Developments for the COVID-19 Pandemic

(2020) Jung-Hyun Won et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

(2020) Merryn Voysey et al.   LANCET

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

(2020) Fernando P. Polack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of Structural and Energetic Differences between Conformations of the SARS-CoV-2 Spike Protein

(2020) Rodrigo A. Moreira et al.   Materials

Covid-19: Pfizer and BioNTech submit vaccine for US authorisation

(2020) Elisabeth Mahase   BMJ-British Medical Journal

Covid-19: What have we learnt about the new variant in the UK?

(2020) Elisabeth Mahase   BMJ-British Medical Journal

Drawing Comparisons between SARS-CoV-2 and the Animal Coronaviruses

(2020) Souvik Ghosh et al.   Microorganisms

Immune Responses to Mucosal Vaccination by the Recombinant S1 and N Proteins of Infectious Bronchitis Virus

(2012) Rosie Meir et al.   VIRAL IMMUNOLOGY

Boosted expression of the SARS-CoV nucleocapsid protein in tobacco and its immunogenicity in mice

(2009) Nuoyan Zheng et al.   VACCINE