A Review of the Progress and Challenges of Developing a Vaccine for COVID-19

The reproductive number of COVID-19 is higher compared to SARS coronavirus

(2020) Ying Liu et al.   JOURNAL OF TRAVEL MEDICINE

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China

(2020) Fei Yu et al.   MICROBES AND INFECTION

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Pandemic Preparedness: Developing Vaccines and Therapeutic Antibodies For COVID-19

(2020) Gregory D. Sempowski et al.   CELL

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Herd Immunity: Understanding COVID-19

(2020) Haley E. Randolph et al.   IMMUNITY

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

The early landscape of COVID‐19 vaccine development in the UK and rest of the world

(2020) Hannah R Sharpe et al.   IMMUNOLOGY

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

(2020) Feng-Cai Zhu et al.   LANCET

Don’t rush to deploy COVID-19 vaccines and drugs without sufficient safety guarantees

(2020) Shibo Jiang   NATURE

The proximal origin of SARS-CoV-2

(2020) Kristian G. Andersen et al.   NATURE MEDICINE

The COVID-19 vaccine development landscape

(2020) Tung Thanh Le et al.   NATURE REVIEWS DRUG DISCOVERY

Developing Covid-19 Vaccines at Pandemic Speed

(2020) Nicole Lurie et al.   NEW ENGLAND JOURNAL OF MEDICINE

T cells found in COVID-19 patients ‘bode well’ for long-term immunity

(2020) Mitch Leslie   SCIENCE

Rapid COVID-19 vaccine development

(2020) Barney S. Graham   SCIENCE

A strategic approach to COVID-19 vaccine R&D

(2020) Lawrence Corey et al.   SCIENCE

Development of an inactivated vaccine candidate for SARS-CoV-2

(2020) Qiang Gao et al.   SCIENCE

Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis

(2020) Alfonso J. Rodriguez-Morales et al.   Travel Medicine and Infectious Disease

The hallmarks of COVID-19 disease

(2020) Daolin Tang et al.   PLoS Pathogens

The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses

(2020) Longping V. Tse et al.   Frontiers in Microbiology

COVID-19: Learning from Lessons To Guide Treatment and Prevention Interventions

(2020) Chris R. Triggle et al.   mSphere

Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear

(2020) Nathan D. Grubaugh et al.   CELL

Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2

(2020) Hui Wang et al.   CELL

A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS

(2020) Lianpan Dai et al.   CELL

Herd immunity or suppression strategy to combat COVID-19

(2020) F. Jung et al.   CLINICAL HEMORHEOLOGY AND MICROCIRCULATION

Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes

(2020) Shengli Xia et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Multivalue ethical framework for fair global allocation of a COVID-19 vaccine

(2020) Yangzi Liu et al.   JOURNAL OF MEDICAL ETHICS

Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial

(2020) Feng-Cai Zhu et al.   LANCET

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

(2020) Pedro M Folegatti et al.   LANCET

Are Genetic Vaccines the Right Weapon against COVID-19?

(2020) Antonella Conforti et al.   MOLECULAR THERAPY

The Improbability of the Rapid Development of a Vaccine for SARS-CoV-2

(2020) Kevin V. Morris   MOLECULAR THERAPY

Coronavirus vaccines leap through safety trials — but which will work is anybody’s guess

(2020) Ewen Callaway   NATURE

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

(2020) Kizzmekia S. Corbett et al.   NATURE

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

(2020) Nina Le Bert et al.   NATURE

Russia’s fast-track coronavirus vaccine draws outrage over safety

(2020) Ewen Callaway   NATURE

Coronavirus vaccine developers wary of errant antibodies

(2020) Ken Garber   NATURE BIOTECHNOLOGY

Ensuring Uptake of Vaccines against SARS-CoV-2

(2020) Michelle M. Mello et al.   NEW ENGLAND JOURNAL OF MEDICINE

Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models

(2020) Meagan E. Deming et al.   NEW ENGLAND JOURNAL OF MEDICINE

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

(2020) Lisa A. Jackson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Coronavirus Disease Pandemic (COVID-19): Challenges and a Global Perspective

(2020) Yashpal Singh Malik et al.   Pathogens

A review of Dengvaxia®: development to deployment

(2019) Stephen J. Thomas et al.   Human Vaccines & Immunotherapeutics

The clinical development process for a novel preventive vaccine: An overview

(2016) K Singh et al.   Journal of Postgraduate Medicine

Bats as reservoirs of severe emerging infectious diseases

(2015) Hui-Ju Han et al.   VIRUS RESEARCH

What you always needed to know about electroporation based DNA vaccines

(2012) Anita Gothelf et al.   Human Vaccines & Immunotherapeutics