Skeletal muscle regeneration via the chemical induction and expansion of myogenic stem cells in situ or in vitro

Injectable Drug‐Releasing Microporous Annealed Particle Scaffolds for Treating Myocardial Infarction

(2020) Jun Fang et al.   ADVANCED FUNCTIONAL MATERIALS

Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy

(2019) Steven S. Welc et al.   Nature Communications

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors

(2018) Ori Bar-Nur et al.   Stem Cell Reports

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy

(2018) Leonela Amoasii et al.   SCIENCE

Incorporation of macrophages into engineered skeletal muscle enables enhanced muscle regeneration

(2018) Mark Juhas et al.   Nature Biomedical Engineering

Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice

(2018) Theresa M. Raimondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs

(2017) Michael R. Hicks et al.   NATURE CELL BIOLOGY

Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss

(2017) Marco Quarta et al.   Nature Communications

The Differentiation Stage of Transplanted Stem Cells Modulates Nerve Regeneration

(2017) Ching-Wen Huang et al.   Scientific Reports

Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal

(2016) Victoria Zismanov et al.   Cell Stem Cell

A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells

(2016) Courtney S. Young et al.   Cell Stem Cell

Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals

(2016) Simon Schwörer et al.   NATURE

Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease

(2016) Albert E. Almada et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory Diseases

(2016) Verena Katharina Raker et al.   Frontiers in Immunology

A XEN-like State Bridges Somatic Cells to Pluripotency during Chemical Reprogramming

(2015) Yang Zhao et al.   CELL

Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion

(2015) Xin Fu et al.   CELL RESEARCH

Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails

(2015) Yanbin Fu et al.   CELL RESEARCH

Direct Conversion of Normal and Alzheimer’s Disease Human Fibroblasts into Neuronal Cells by Small Molecules

(2015) Wenxiang Hu et al.   Cell Stem Cell

Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy

(2015) Jérome Chal et al.   NATURE BIOTECHNOLOGY

Shifts in macrophage cytokine production drive muscle fibrosis

(2015) James G Tidball et al.   NATURE MEDICINE

The central role of muscle stem cells in regenerative failure with aging

(2015) Helen M Blau et al.   NATURE MEDICINE

Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting

(2015) Ling Liu et al.   Nature Protocols

Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity

(2015) Prabhat K. Singhal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy

(2015) C. Long et al.   SCIENCE

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Stem cell aging: mechanisms, regulators and therapeutic opportunities

(2014) Juhyun Oh et al.   NATURE MEDICINE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

(2014) Jennifer D Bernet et al.   NATURE MEDICINE

An Acellular Biologic Scaffold Promotes Skeletal Muscle Formation in Mice and Humans with Volumetric Muscle Loss

(2014) B. M. Sicari et al.   Science Translational Medicine

A Zebrafish Embryo Culture System Defines Factors that Promote Vertebrate Myogenesis across Species

(2013) Cong Xu et al.   CELL

Chemical Approaches to Stem Cell Biology and Therapeutics

(2013) Wenlin Li et al.   Cell Stem Cell

Muscular dystrophies

(2013) Eugenio Mercuri et al.   LANCET

Vitamin C modulates TET1 function during somatic cell reprogramming

(2013) Jiekai Chen et al.   NATURE GENETICS

Satellite Cells and the Muscle Stem Cell Niche

(2013) Hang Yin et al.   PHYSIOLOGICAL REVIEWS

Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds

(2013) P. Hou et al.   SCIENCE

The aged niche disrupts muscle stem cell quiescence

(2012) Joe V. Chakkalakal et al.   NATURE

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

Morphometric and Histopathologic Changes in Skeletal Muscle Induced for Injectable PLGA Microparticles

(2011) Luis Acuña et al.   INTERNATIONAL JOURNAL OF MORPHOLOGY

Fiber Types in Mammalian Skeletal Muscles

(2011) Stefano Schiaffino et al.   PHYSIOLOGICAL REVIEWS

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

(2010) Miguel Angel Esteban et al.   Cell Stem Cell

Regulation and dysregulation of fibrosis in skeletal muscle

(2010) Antonio L. Serrano et al.   EXPERIMENTAL CELL RESEARCH

A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

(2009) Justin K. Ichida et al.   Cell Stem Cell

Skeletal Myogenic Potential of Mouse Skin-Derived Precursors

(2009) Zhifang Qiu et al.   STEM CELLS AND DEVELOPMENT

Highly Efficient, Functional Engraftment of Skeletal Muscle Stem Cells in Dystrophic Muscles

(2008) Massimiliano Cerletti et al.   CELL

Self-renewal and expansion of single transplanted muscle stem cells

(2008) Alessandra Sacco et al.   NATURE

Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice

(2008) Ulrike Lichti et al.   Nature Protocols

Isolation of a slowly adhering cell fraction containing stem cells from murine skeletal muscle by the preplate technique

(2008) Burhan Gharaibeh et al.   Nature Protocols

The Muscle Stem Cell Niche: Regulation of Satellite Cells During Regeneration

(2008) Kristel J.M. Boonen et al.   TISSUE ENGINEERING PART B-REVIEWS