Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-26
DOI
10.1038/s41467-019-10614-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Macrophages escape Klotho gene silencing in the mdx mouse model of Duchenne muscular dystrophy and promote muscle growth and increase satellite cell numbers through a Klotho-mediated pathway
- (2017) Michelle Wehling-Henricks et al. HUMAN MOLECULAR GENETICS
- Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis
- (2016) Alisa A. Mueller et al. NATURE
- Increases of M2a macrophages and fibrosis in aging muscle are influenced by bone marrow aging and negatively regulated by muscle-derived nitric oxide
- (2015) Ying Wang et al. AGING CELL
- Phenotypic Characterization of Speed-Associated Gait Changes in Mice Reveals Modular Organization of Locomotor Networks
- (2015) Carmelo Bellardita et al. CURRENT BIOLOGY
- Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors
- (2015) Dario R Lemos et al. NATURE MEDICINE
- Inflammatory monocytes promote progression of Duchenne muscular dystrophy and can be therapeutically targeted via CCR2
- (2014) K. Mojumdar et al. EMBO Molecular Medicine
- A Wnt-TGF 2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice
- (2014) S. Biressi et al. Science Translational Medicine
- Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy
- (2013) Maria Gabriela Morales et al. HUMAN MOLECULAR GENETICS
- A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and functionin vitroandin vivo
- (2013) Christina E. Arnold et al. IMMUNOLOGY
- Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation
- (2013) Yan Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An anti-inflammatory role for leukemia inhibitory factor receptor signaling in regenerating skeletal muscle
- (2012) Liam C. Hunt et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Macrophage plasticity and polarization: in vivo veritas
- (2012) Antonio Sica et al. JOURNAL OF CLINICAL INVESTIGATION
- SOCS3 Deficiency Promotes M1 Macrophage Polarization and Inflammation
- (2012) H. Qin et al. JOURNAL OF IMMUNOLOGY
- Heat Shock Protein 47: A Novel Biomarker of Phenotypically Altered Collagen-Producing Cells
- (2011) Takashi Taguchi et al. ACTA HISTOCHEMICA ET CYTOCHEMICA
- Inhibiting TGF-β Activity Improves Respiratory Function in mdx Mice
- (2011) Carol A. Nelson et al. AMERICAN JOURNAL OF PATHOLOGY
- Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle
- (2011) A. Uezumi et al. JOURNAL OF CELL SCIENCE
- IFN-γ Promotes Muscle Damage in the mdx Mouse Model of Duchenne Muscular Dystrophy by Suppressing M2 Macrophage Activation and Inhibiting Muscle Cell Proliferation
- (2011) S. Armando Villalta et al. JOURNAL OF IMMUNOLOGY
- Regulation of skeletal muscle regeneration by CCR2-activating chemokines is directly related to macrophage recruitment
- (2010) Carlo O. Martinez et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype
- (2010) S. A. Villalta et al. HUMAN MOLECULAR GENETICS
- Transforming Growth Factor-β1 Induces Transdifferentiation of Myoblasts into Myofibroblasts via Up-Regulation of Sphingosine Kinase-1/S1P3 Axis
- (2010) Francesca Cencetti et al. MOLECULAR BIOLOGY OF THE CELL
- Prevention of muscle fibrosis and myonecrosis inmdxmice by suramin, a TGF-β1 blocker
- (2010) Ana Paula Tiemi Taniguti et al. MUSCLE & NERVE
- Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle
- (2010) Akiyoshi Uezumi et al. NATURE CELL BIOLOGY
- Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
- (2010) Aaron W. B. Joe et al. NATURE CELL BIOLOGY
- Arginine Metabolism by Macrophages Promotes Cardiac and Muscle Fibrosis in mdx Muscular Dystrophy
- (2010) Michelle Wehling-Henricks et al. PLoS One
- Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF-β1 treatment
- (2009) Simona Zanotti et al. CELL AND TISSUE RESEARCH
- The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
- (2009) S. A. Bustin et al. CLINICAL CHEMISTRY
- Suppression of macrophage functions impairs skeletal muscle regeneration with severe fibrosis
- (2008) M SEGAWA et al. EXPERIMENTAL CELL RESEARCH
- Fibrinogen drives dystrophic muscle fibrosis via a TGF /alternative macrophage activation pathway
- (2008) B. Vidal et al. GENES & DEVELOPMENT
- Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy
- (2008) S. A. Villalta et al. HUMAN MOLECULAR GENETICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started