Blueberries and insulin protect microglial cells against high glucose-induced inflammation and restore GLUT-1

Glucose transporter 1 critically controls microglial activation through facilitating glycolysis

(2019) Luxi Wang et al.   Molecular Neurodegeneration

Role of microglia-neuron interactions in diabetic encephalopathy

(2018) Yuan Liu et al.   AGEING RESEARCH REVIEWS

Antioxidant and Anti-Inflammatory Effects of Blueberry Anthocyanins on High Glucose-Induced Human Retinal Capillary Endothelial Cells

(2018) Wuyang Huang et al.   Oxidative Medicine and Cellular Longevity

The significance of anthocyanins in the prevention and treatment of type 2 diabetes

(2018) Dorota Różańska et al.   Advances in Clinical and Experimental Medicine

The effects of insulin on the inflammatory activity of BV2 microglia

(2018) Fiona Brabazon et al.   PLoS One

The Immunomodulatory and Anti-Inflammatory Role of Polyphenols

(2018) Nour Yahfoufi et al.   Nutrients

Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial

(2017) Marshall G. Miller et al.   EUROPEAN JOURNAL OF NUTRITION

Bioenergetic regulation of microglia

(2017) Soumitra Ghosh et al.   GLIA

Metabolic Effects of Berries with Structurally Diverse Anthocyanins

(2017) John Overall et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dietary Anthocyanins and Insulin Resistance: When Food Becomes a Medicine

(2017) Tarun Belwal et al.   Nutrients

Lipid Accumulation in HepG2 Cells Is Attenuated by Strawberry Extract through AMPK Activation

(2017) Tamara Forbes-Hernández et al.   Nutrients

The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing

(2015) Barbara Shukitt-Hale et al.   BRITISH JOURNAL OF NUTRITION

Emerging Role of Nitric Oxide and Heat Shock Proteins in Insulin Resistance

(2015) Marisa Nile Molina et al.   CURRENT HYPERTENSION REPORTS

Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease

(2015) Giuseppe Verdile et al.   MEDIATORS OF INFLAMMATION

High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity

(2015) Zhigang Liu et al.   PLoS One

Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling

(2015) Marco Mainardi et al.   NEURAL PLASTICITY

Glucose regulation, cognition, and brain MRI in type 2 diabetes: a systematic review

(2015) Stefan L C Geijselaers et al.   Lancet Diabetes & Endocrinology

The impact of glucose disorders on cognition and brain volumes in the elderly: the Sydney Memory and Ageing Study

(2014) Katherine Samaras et al.   AGE

Protective effects of blueberry- and strawberry diets on neuronal stress following exposure to 56Fe particles

(2014) Shibu M. Poulose et al.   BRAIN RESEARCH

Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces Aβ level and microglia activation in the brains of 3xTg-AD mice

(2014) Yanxing Chen et al.   EXPERIMENTAL NEUROLOGY

NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?

(2014) Evan A. Bordt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions

(2014) Philip G. Nijland et al.   GLIA

Critical illness-induced dysglycemia and the brain

(2014) Romain Sonneville et al.   INTENSIVE CARE MEDICINE

Blueberry Supplementation Improves Memory in Middle-Aged Mice Fed a High-Fat Diet

(2014) Amanda N. Carey et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Berries: Anti-inflammatory Effects in Humans

(2014) Shama V. Joseph et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Wild Blueberries (Vaccinium myrtillus) Alleviate Inflammation and Hypertension Associated with Developing Obesity in Mice Fed with a High-Fat Diet

(2014) Otto T. Mykkänen et al.   PLoS One

Over-production of nitric oxide by oxidative stress-induced activation of the TGF-β1/PI3K/Akt pathway in mesangial cells cultured in high glucose

(2013) Yun-peng Zhai et al.   ACTA PHARMACOLOGICA SINICA

Insulin-like growth factor-1 abrogates microglial oxidative stress and TNF-α responses to spreading depression

(2013) Yelena Y. Grinberg et al.   JOURNAL OF NEUROCHEMISTRY

Restoration of stressor-induced calcium dysregulation and autophagy inhibition by polyphenol-rich açaí (Euterpe spp.) fruit pulp extracts in rodent brain cells in vitro

(2013) Shibu M. Poulose et al.   NUTRITION

High glucose enhances LPS-stimulated human PMVEC hyperpermeability via the NO pathway

(2013) XIU-JUAN LIU et al.   Experimental and Therapeutic Medicine

Cerebrospinal Fluid Analysis in the Workup of GLUT1 Deficiency Syndrome

(2013) Wilhelmina G. Leen et al.   JAMA Neurology

Dietary flavonoid intakes and risk of type 2 diabetes in US men and women

(2012) Nicole M Wedick et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Rosiglitazone attenuates NF-κB-mediated Nox4 upregulation in hyperglycemia-activated endothelial cells

(2012) Clintoria R. Williams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Targeting NOX enzymes in the central nervous system: therapeutic opportunities

(2012) Silvia Sorce et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Anthocyanin-rich Açai (Euterpe oleracea Mart.) Fruit Pulp Fractions Attenuate Inflammatory Stress Signaling in Mouse Brain BV-2 Microglial Cells

(2012) Shibu M. Poulose et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Impact of Hyperglycemia on Neuropathological Alterations during Critical Illness

(2012) Romain Sonneville et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Changes in insulin-signaling transduction pathway underlie learning/memory deficits in an Alzheimer’s disease rat model

(2012) Xiaojuan Han et al.   JOURNAL OF NEURAL TRANSMISSION

A Nonpolar Blueberry Fraction Blunts NADPH Oxidase Activation in Neuronal Cells Exposed to Tumor Necrosis Factor-α

(2012) Sally J. Gustafson et al.   Oxidative Medicine and Cellular Longevity

Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats

(2012) Catarina Rendeiro et al.   PSYCHOPHARMACOLOGY

Insulin resistance in the nervous system

(2012) Bhumsoo Kim et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

An extract of chokeberry attenuates weight gain and modulates insulin, adipogenic and inflammatory signalling pathways in epididymal adipose tissue of rats fed a fructose-rich diet

(2011) Bolin Qin et al.   BRITISH JOURNAL OF NUTRITION

Role of microglia in CNS inflammation

(2011) Manuel B. Graeber et al.   FEBS LETTERS

A Blueberry-Enriched Diet Attenuates Nephropathy in a Rat Model of Hypertension via Reduction in Oxidative Stress

(2011) Carrie M. Elks et al.   PLoS One

Anthocyanins from purple sweet potato attenuate dimethylnitrosamine-induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression

(2010) Yong Pil Hwang et al.   FOOD AND CHEMICAL TOXICOLOGY

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract☆

(2009) Gregory J. Brewer et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Proinflammatory cytokines provoke oxidative damage to actin in neuronal cells mediated by Rac1 and NADPH oxidase

(2009) Brian M. Barth et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

(2008) Sang Won Suh et al.   ANNALS OF NEUROLOGY