Platelet Microparticles Protect Acute Myelogenous Leukemia Cells against Daunorubicin-Induced Apoptosis

CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms

(2020) Margaretha A. Skowron et al.   BRITISH JOURNAL OF CANCER

Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia

(2020) Tobias Herold et al.   LEUKEMIA

Platelets Extracellular Vesicles as Regulators of Cancer Progression—An Updated Perspective

(2020) Magdalena Żmigrodzka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Transcriptional Network That Controls Growth Arrest and Macrophage Differentiation in the Human Myeloid Leukemia Cell Line THP-1

(2020) Iveta Gažová et al.   Frontiers in Cell and Developmental Biology

Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture

(2020) Eleanor Wendy Trotter et al.   Open Biology

Time dependent response of daunorubicin on cytotoxicity, cell cycle and DNA repair in acute lymphoblastic leukaemia

(2019) Hussain Mubarak Al-Aamri et al.   BMC CANCER

Platelets, Thrombo-Inflammation, and Cancer: Collaborating With the Enemy

(2019) Ana Luisa Palacios-Acedo et al.   Frontiers in Immunology

miRDB: an online database for prediction of functional microRNA targets

(2019) Yuhao Chen et al.   NUCLEIC ACIDS RESEARCH

The interaction of platelets with colorectal cancer cells inhibits tumor growth but promotes metastasis

(2019) Léa Plantureux et al.   CANCER RESEARCH

Platelet microparticle delivered microRNA-Let-7a promotes the angiogenic switch

(2018) Chinedu Anene et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

RNA sequencing enables systematic identification of platelet transcriptomic alterations in NSCLC patients

(2018) Qun Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Associations between aspirin use and the risk of cancers: a meta-analysis of observational studies

(2018) Yan Qiao et al.   BMC CANCER

Dissecting the biochemical architecture and morphological release pathways of the human platelet extracellular vesiculome

(2018) Silvia H. De Paoli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults

(2018) Martin E. M. Parsons et al.   PROTEOMICS

MiR-125a-5p functions as a tumour suppressor in breast cancer by downregulating BAP1

(2018) Liang Yan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives

(2018) Jessica Marinello et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia

(2017) Emilia L. Lim et al.   JOURNAL OF CLINICAL ONCOLOGY

The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro

(2017) Martina Bernardi et al.   Journal of Translational Medicine

Standardization of platelet releasate products for clinical applications in cell therapy: a mathematical approach

(2017) Francesco Agostini et al.   Journal of Translational Medicine

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

(2017) Avi Ashkenazi et al.   NATURE REVIEWS DRUG DISCOVERY

Comparison of the release of microRNAs and extracellular vesicles from platelets in response to different agonists

(2017) Ashley R. Ambrose et al.   PLATELETS

Analysis of platelet-derived extracellular vesicles in plateletpheresis concentrates: a multicenter study

(2017) Anne Black et al.   TRANSFUSION

Involvement of miR-125a in resistance to daunorubicin by inhibiting apoptosis in leukemia cell lines

(2017) Haitao Bai et al.   TUMOR BIOLOGY

Platelet microparticle-mediated transfer of miR-939 to epithelial ovarian cancer cells promotes epithelial to mesenchymal transition

(2017) Meiling Tang et al.   Oncotarget

microRNAs and Acute Myeloid Leukemia Chemoresistance: A Mechanistic Overview

(2017) Martino Marco Gabra et al.   Frontiers in Oncology

A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis

(2017) Ai Takemoto et al.   Scientific Reports

The role of platelets in the tumor microenvironment: From solid tumors to leukemia

(2016) MengJie Yan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

(2016) Hartmut Döhner et al.   BLOOD

Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane

(2016) Katelyn L. O'Neill et al.   GENES & DEVELOPMENT

Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study

(2016) Simer J. Bains et al.   JOURNAL OF CLINICAL ONCOLOGY

A 17-gene stemness score for rapid determination of risk in acute leukaemia

(2016) Stanley W. K. Ng et al.   NATURE

Transcriptomic profiling of platelet senescence and platelet extracellular vesicles

(2016) Annika Pienimaeki-Roemer et al.   TRANSFUSION

Antiplatelet Agents Inhibit the Generation of Platelet-Derived Microparticles

(2016) Alice Giacomazzi et al.   Frontiers in Pharmacology

Population-wide Impact of Long-term Use of Aspirin and the Risk for Cancer

(2016) Yin Cao et al.   JAMA Oncology

Acute myeloid leukemia-Major progress over four decades and glimpses into the future

(2015) Hagop Kantarjian   AMERICAN JOURNAL OF HEMATOLOGY

miR-125a-5p inhibits cell proliferation and induces apoptosis in colon cancer via targeting BCL2, BCL2L12 and MCL1

(2015) Zhiguo Tong et al.   BIOMEDICINE & PHARMACOTHERAPY

A randomized comparison of daunorubicin 90 mg/m 2 vs 60 mg/m 2 in AML induction: results from the UK NCRI AML17 trial in 1206 patients

(2015) Alan K. Burnett et al.   BLOOD

Standardized counting of circulating platelet microparticles using currently available flow cytometers and scatter-based triggering: Forward or side scatter?

(2015) P. Poncelet et al.   CYTOMETRY PART A

MicroRNA-223 delivered by platelet-derived microvesicles promotes lung cancer cell invasion via targeting tumor suppressor EPB41L3

(2015) Hongwei Liang et al.   Molecular Cancer

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

microRNA-125b promotes leukemia cell resistance to daunorubicin by inhibiting apoptosis

(2014) LILI ZHOU et al.   Molecular Medicine Reports

Activated platelets can deliver mRNA regulatory Ago2bulletmicroRNA complexes to endothelial cells via microparticles

(2013) B. Laffont et al.   BLOOD

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

(2013) M. Yu et al.   SCIENCE

Platelets and platelet-like particles mediate intercellular RNA transfer

(2012) A. Risitano et al.   BLOOD

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Inverse relationship between leukaemic cell burden and plasma concentrations of daunorubicin in patients with acute myeloid leukaemia

(2010) Alex Bogason et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice

(2010) Jean-Emmanuel Sarry et al.   JOURNAL OF CLINICAL INVESTIGATION

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

Platelet-Derived Transforming Growth Factor-  Down-Regulates NKG2D Thereby Inhibiting Natural Killer Cell Antitumor Reactivity

(2009) H.-G. Kopp et al.   CANCER RESEARCH

Aspirin Use and Survival After Diagnosis of Colorectal Cancer

(2009) Andrew T. Chan   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY