Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-05-07
DOI
10.3389/fimmu.2021.659339
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Structure analysis of the receptor binding of 2019-nCoV
- (2020) Yun Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China
- (2020) Zunyou Wu et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- COVID-19 and the cardiovascular system
- (2020) Ying-Ying Zheng et al. Nature Reviews Cardiology
- Clinical Characteristics of Coronavirus Disease 2019 in China
- (2020) Wei-jie Guan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools
- (2020) Yajing Fu et al. VIROLOGICA SINICA
- COVID-19 with Different Severities: A Multicenter Study of Clinical Features
- (2020) Yun Feng et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
- (2020) B. Coutard et al. ANTIVIRAL RESEARCH
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Protective humoral immunity in SARS-CoV-2 infected pediatric patients
- (2020) Yaguang Zhang et al. Cellular & Molecular Immunology
- Role of the renin–angiotensin system in kidney development and programming of adult blood pressure
- (2020) Lucas F. Almeida et al. CLINICAL SCIENCE
- Will children reveal their secret? The coronavirus dilemma
- (2020) Luca Cristiani et al. EUROPEAN RESPIRATORY JOURNAL
- Transmission potential and severity of COVID-19 in South Korea
- (2020) Eunha Shim et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-Chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males?
- (2020) Donato Gemmati et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Clinical Implications of SARS-Cov2 Interaction with Renin Angiotensin System
- (2020) Agnieszka Brojakowska et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Molecular and Cellular Differences in Cardiac Repair of Male and Female Mice
- (2020) Amanda B. Pullen et al. Journal of the American Heart Association
- COVID-19 and smoking: A systematic review of the evidence
- (2020) Constantine Vardavas et al. Tobacco Induced Diseases
- Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020
- (2020) Shikha Garg et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Neuropilin1 Expression Acts as a Prognostic Marker in Stomach Adenocarcinoma by Predicting the Infiltration of Treg Cells and M2 Macrophages
- (2020) Ji Young Kang et al. Journal of Clinical Medicine
- SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes
- (2020) Janko Nikolich-Zugich et al. GeroScience
- Gender Differences in Patients With COVID-19: Focus on Severity and Mortality
- (2020) Jian-Min Jin et al. Frontiers in Public Health
- ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy
- (2020) Rosanna Asselta et al. Aging-US
- Distribution of ACE2, CD147, CD26 and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID‐19 risk factors
- (2020) U. Radzikowska et al. ALLERGY
- The pivotal role of TMPRSS2 in coronavirus disease 2019 and prostate cancer
- (2020) Veronica Mollica et al. Future Oncology
- SARS-Cov-2 infection: Response of human immune system and possible implications for the rapid test and treatment
- (2020) di Mauro Gabriella et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Encouraging results from phase 1/2 COVID-19 vaccine trials
- (2020) Naor Bar-Zeev et al. LANCET
- Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
- (2020) Pedro M Folegatti et al. LANCET
- Sex-differences in mortality rates and underlying conditions for COVID-19 deaths in England and Wales
- (2020) Mohamed O. Mohamed et al. MAYO CLINIC PROCEEDINGS
- An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
- (2020) Lisa A. Jackson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling
- (2020) Zena Wehbe et al. Frontiers in Pharmacology
- Overview of Immune Response During SARS-CoV-2 Infection: Lessons From the Past
- (2020) Vibhuti Kumar Shah et al. Frontiers in Immunology
- The COVID-19 Cytokine Storm; What We Know So Far
- (2020) Dina Ragab et al. Frontiers in Immunology
- Clinicopathological Significance of Neuropilin 1 Expression in Gastric Cancer: A Meta-Analysis
- (2020) Hui Cao et al. DISEASE MARKERS
- SARS-CoV-2 vaccines in development
- (2020) Florian Krammer NATURE
- Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
- (2020) Ludovico Cantuti-Castelvetri et al. SCIENCE
- The key role of Warburg effect in SARS-CoV-2 replication and associated inflammatory response
- (2020) Philippe Icard et al. BIOCHIMIE
- Classical and alternative receptors for SARS‐CoV‐2 therapeutic strategy
- (2020) Siti Fathiah Masre et al. REVIEWS IN MEDICAL VIROLOGY
- Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis
- (2019) Rafal P. Piprek et al. DEVELOPMENT GENES AND EVOLUTION
- The metalloprotease ADAM17 in inflammation and cancer
- (2019) Stefan Düsterhöft et al. PATHOLOGY RESEARCH AND PRACTICE
- Cardiovascular Disease and the Female Disadvantage
- (2019) Mark Woodward International Journal of Environmental Research and Public Health
- A Structure-Informed Atlas of Human-Virus Interactions
- (2019) Gorka Lasso et al. CELL
- Counter-regulatory renin–angiotensin system in cardiovascular disease
- (2019) Maria Paz Ocaranza et al. Nature Reviews Cardiology
- The Renin-Angiotensin System and the Cerebrovascular Diseases: Experimental and Clinical Evidence
- (2019) Lucas M. Kangussu et al. PROTEIN AND PEPTIDE LETTERS
- TB epidemiology: where are the young women? Know your tuberculosis epidemic, know your response
- (2018) Rubeshan Perumal et al. BMC PUBLIC HEALTH
- RAS in the central nervous system: Potential role in neuropsychiatric disorders
- (2018) Natalia Pessoa Rocha et al. CURRENT MEDICINAL CHEMISTRY
- Effect of sex on vaccination outcomes: important but frequently overlooked
- (2018) Alice Harper et al. CURRENT OPINION IN PHARMACOLOGY
- The Confluence of Sex Hormones and Aging on Immunity
- (2018) Melanie R. Gubbels Bupp et al. Frontiers in Immunology
- Sex differences in vaccine-induced humoral immunity
- (2018) Stephanie Fischinger et al. Seminars in Immunopathology
- Repurposing Estrogen Receptor Antagonists for the Treatment of Infectious Disease
- (2018) Marhiah C. Montoya et al. mBio
- Sex-Dependent Outcome of Hepatitis B and C Viruses Infections: Synergy of Sex Hormones and Immune Responses?
- (2018) Anna Ruggieri et al. Frontiers in Immunology
- Sex differences in immune responses: Hormonal effects, antagonistic selection, and evolutionary consequences
- (2017) Jacob Roved et al. HORMONES AND BEHAVIOR
- Ironing out sex differences in tuberculosis prevalence
- (2017) Tom A. Yates et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Sex Drives Dimorphic Immune Responses to Viral Infections
- (2017) Soumitra Ghosh et al. JOURNAL OF IMMUNOLOGY
- Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection
- (2017) Rudragouda Channappanavar et al. JOURNAL OF IMMUNOLOGY
- Effects of sex and generation on hepatitis B viral load in families with hepatocellular carcinoma
- (2017) Ai-Ru Hsieh et al. WORLD JOURNAL OF GASTROENTEROLOGY
- CD147 expression was positively linked to aggressiveness and worse prognosis of gastric cancer: a meta and bioinformatics analysis
- (2017) Hua-Chuan Zheng et al. Oncotarget
- Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors
- (2016) Jackye Peretz et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Estrogen Accelerates Cutaneous Wound Healing by Promoting Proliferation of Epidermal Keratinocytes via Erk/Akt Signaling Pathway
- (2016) Tao Zhou et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- 17β-Oestradiol enhances the expansion and activation of myeloid-derived suppressor cells via signal transducer and activator of transcription (STAT)−3 signalling in human pregnancy
- (2016) T. Pan et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The host immune response in respiratory virus infection: balancing virus clearance and immunopathology
- (2016) Amy H. Newton et al. Seminars in Immunopathology
- Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?
- (2016) Feifei Qiu et al. Oncotarget
- CXCR7/p-ERK-Signaling Is a Novel Target for Therapeutic Vasculogenesis in Patients with Coronary Artery Disease
- (2016) Zheng Cao et al. PLoS One
- Differences in angiotensin (1–7) between men and women
- (2015) Jennifer C. Sullivan et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- 17β-Estradiol enhances the activation of IFN-α signaling in B cells by down-regulating the expression of let-7e-5p, miR-98-5p and miR-145a-5p that target IKKε
- (2015) Guanjun Dong et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Estrogen receptors regulate innate immune cells and signaling pathways
- (2015) Susan Kovats CELLULAR IMMUNOLOGY
- Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma
- (2015) JING LU et al. Molecular Medicine Reports
- Sex and Gender Impact Immune Responses to Vaccines Among the Elderly
- (2015) Ashley L. Fink et al. PHYSIOLOGY
- Sex-based differences in immune function and responses to vaccination
- (2015) S. L. Klein et al. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
- Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer
- (2015) Jin-Hang Gao et al. Scientific Reports
- A Meta-Analysis of Cigarette Smoking Prevalence among Adolescents in China: 1981–2010
- (2015) Juan Han et al. International Journal of Environmental Research and Public Health
- Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection
- (2014) Julie Dyall et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The number of X chromosomes influences protection from cardiac ischaemia/reperfusion injury in mice: one X is better than two
- (2014) J. Li et al. CARDIOVASCULAR RESEARCH
- Analysis of ADAM17 Polymorphisms and Susceptibility to Sporadic Abdominal Aortic Aneurysm
- (2014) You Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Biological Differences Between the Sexes and Susceptibility to Tuberculosis
- (2014) S. Nhamoyebonde et al. JOURNAL OF INFECTIOUS DISEASES
- Renin–angiotensin–aldosterone system gender differences in an Afro-Caribbean population
- (2014) Damian H Cohall et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- 17 -Estradiol Protects Females against Influenza by Recruiting Neutrophils and Increasing Virus-Specific CD8 T Cell Responses in the Lungs
- (2014) D. P. Robinson et al. JOURNAL OF VIROLOGY
- Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy
- (2014) Daisuke Nakada et al. NATURE
- Sex Hormones and Immune Dimorphism
- (2014) Aruna Bhatia et al. TheScientificWorldJOURNAL
- Age and gender differences in the prevalence and patterns of multimorbidity in the older population
- (2014) José María Abad-Díez et al. BMC Geriatrics
- The role of ADAM17 in metabolic inflammation
- (2013) Rossella Menghini et al. ATHEROSCLEROSIS
- ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis
- (2013) AC Simões e Silva et al. BRITISH JOURNAL OF PHARMACOLOGY
- Neuropilin-1 expression in squamous cell carcinoma of the oesophagus
- (2013) Mohamed Alattar et al. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
- Viral infection of the lung: Host response and sequelae
- (2013) Jae-Kwang Yoo et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Androgen Regulation of the TMPRSS2 Gene and the Effect of a SNP in an Androgen Response Element
- (2013) Liesbeth Clinckemalie et al. MOLECULAR ENDOCRINOLOGY
- Negative Association between Testosterone Concentration and Inflammatory Markers in Young Men: A Nested Cross-Sectional Study
- (2013) Johannes Bobjer et al. PLoS One
- FDA-Approved Selective Estrogen Receptor Modulators Inhibit Ebola Virus Infection
- (2013) L. M. Johansen et al. Science Translational Medicine
- TheERK1/2Inhibitor U0126 Attenuates Diabetes-Induced Upregulation of MMP-9 and Biomarkers of Inflammation in the Retina
- (2013) Ghulam Mohammad et al. Journal of Diabetes Research
- Sex influences immune responses to viruses, and efficacy of prophylaxis and treatments for viral diseases
- (2012) Sabra L. Klein BIOESSAYS
- Selective estrogen receptor modulators inhibit hepatitis C virus infection at multiple steps of the virus life cycle
- (2012) Yuko Murakami et al. MICROBES AND INFECTION
- Smoking, BCG and Employment and the Risk of Tuberculosis Infection in HIV-Infected Persons in South Africa
- (2012) Tolu Oni et al. PLoS One
- 17β-estradiol induces CD40 expression in dendritic cells via MAPK signaling pathways in a minichromosome maintenance protein 6-dependent manner
- (2011) Hao Xie et al. ARTHRITIS AND RHEUMATISM
- SARS-CoV Accessory Protein 3b Induces AP-1 Transcriptional Activity through Activation of JNK and ERK Pathways
- (2011) Bhavna Varshney et al. BIOCHEMISTRY
- The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor signaling
- (2011) C. Seillet et al. BLOOD
- Cellular and molecular mechanisms involved in hepatocellular carcinoma gender disparity
- (2010) Anna Ruggieri et al. INTERNATIONAL JOURNAL OF CANCER
- Estradiol Suppresses NF- B Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages
- (2010) A. J. Murphy et al. JOURNAL OF IMMUNOLOGY
- The Xs and Y of immune responses to viral vaccines
- (2010) Sabra L Klein et al. LANCET INFECTIOUS DISEASES
- 17β-estradiol inhibits the production of infectious particles of hepatitis C virus
- (2010) Kazumi Hayashida et al. MICROBIOLOGY AND IMMUNOLOGY
- Drinking pattern and socio-cultural aspects on immune response: an overview
- (2010) Javier Romeo et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia
- (2009) Hong Peng Jia et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Macrophages
- (2009) Barbro N. Melgert et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Stronger inflammatory/cytotoxic T-cell response in women identified by microarray analysis
- (2009) A Hewagama et al. GENES AND IMMUNITY
- Gender-Dependent Differential Phosphorylation in the ERK Signaling Pathway is Associated with Increased MMP2 Activity in Rat Aortic Smooth Muscle Cells
- (2009) Lauren K. Ehrlichman et al. JOURNAL OF SURGICAL RESEARCH
- Activity and intracellular location of estrogen receptors α and β in human bronchial epithelial cells
- (2009) Margarita M. Ivanova et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets
- (2008) Anthony J. Muslin CLINICAL SCIENCE
- Interferon and cytokine responses to SARS-coronavirus infection
- (2008) Volker Thiel et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Modulation of TNF- -converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF- production and facilitates viral entry
- (2008) S. Haga et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma
- (2008) C. Pergola et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now