PC12 and THP-1 Cell Lines as Neuronal and Microglia Model in Neurobiological Research

PC12 Cell Line: Cell Types, Coating of Culture Vessels, Differentiation and Other Culture Conditions

(2020) Benita Wiatrak et al.   Cells

In vitro Models of Neurodegenerative Diseases

(2020) Anna Slanzi et al.   Frontiers in Cell and Developmental Biology

Inflammatory mechanisms in neurodegeneration

(2019) Michael R. Nichols et al.   JOURNAL OF NEUROCHEMISTRY

Resveratrol alleviates lipopolysaccharide-induced inflammation in PC-12 cells and in rat model

(2019) Guiqi Zhang et al.   BMC BIOTECHNOLOGY

Lipopolysaccharide-Induced Neuroinflammation as a Bridge to Understand Neurodegeneration

(2019) Carla Ribeiro Alvares Batista et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Geniposide protects PC12 cells from lipopolysaccharide-evoked inflammatory injury via up-regulation of miR-145-5p

(2019) Shaolong Ma et al.   Artificial Cells Nanomedicine and Biotechnology

Novel cannabis flavonoid, cannflavin A displays both a hormetic and neuroprotective profile against amyloid β-mediated neurotoxicity in PC12 cells: Comparison with geranylated flavonoids, mimulone and diplacone

(2019) Carly Eggers et al.   BIOCHEMICAL PHARMACOLOGY

Partial Protection of Paclitaxel-induced Neurotoxicity by Antioxidants

(2018) YAEKO HARA et al.   IN VIVO

Change in Anticancer Drug Sensitivity During Neuronal Differentiation of PC12 Cells

(2018) HIROSHI SAKAGAMI et al.   IN VIVO

Microglia-Mediated Synapse Loss in Alzheimer's Disease

(2018) Lawrence Rajendran et al.   JOURNAL OF NEUROSCIENCE

The phorbol 12-myristate-13-acetate differentiation protocol is critical to the interaction of THP-1 macrophages with Salmonella Typhimurium

(2018) Tregei Starr et al.   PLoS One

The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease

(2018) Holly M. Brothers et al.   Frontiers in Aging Neuroscience

Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization?

(2018) Serena Tedesco et al.   Frontiers in Pharmacology

The antimicrobial protection hypothesis of Alzheimer's disease

(2018) Robert D. Moir et al.   Alzheimers & Dementia

Neuroinflammation in the central nervous system: Symphony of glial cells

(2018) Qiao‐qiao Yang et al.   GLIA

Microglia in Alzheimer’s disease

(2017) David V. Hansen et al.   JOURNAL OF CELL BIOLOGY

5-HT6 Receptor Agonist and Antagonist Against β-Amyloid-Peptide-Induced Neurotoxicity in PC-12 Cells

(2017) Anand M. Bokare et al.   NEUROCHEMICAL RESEARCH

Developmental neurotoxicity of different pesticides in PC-12 cells in vitro

(2017) Verena Christen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus

(2016) Maria E. Lund et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Potential role of antimicrobial peptides in the early onset of Alzheimer's disease

(2015) Mick M. Welling et al.   Alzheimers & Dementia

The neuritogenic and neuroprotective potential of senegenin against Aβ-induced neurotoxicity in PC 12 cells

(2015) Robert Jesky et al.   BMC Complementary and Alternative Medicine

Icariin Prevents Amyloid Beta-Induced Apoptosis via the PI3K/Akt Pathway in PC-12 Cells

(2015) Dongdong Zhang et al.   Evidence-based Complementary and Alternative Medicine

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease

(2015) Myles R. Minter et al.   JOURNAL OF NEUROCHEMISTRY

THP-1 cell line: An in vitro cell model for immune modulation approach

(2014) Wasaporn Chanput et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Advantages and disadvantages of the animal models v. in vitro studies in iron metabolism: a review

(2013) Y. García et al.   Animal

Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease

(2013) Zhiyou Cai et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Curcumin reduces cisplatin-induced neurotoxicity in NGF-differentiated PC12 cells

(2012) Leonardo Meneghin Mendonça et al.   NEUROTOXICOLOGY

Neoechinulin A suppresses amyloid-β oligomer-induced microglia activation and thereby protects PC-12 cells from inflammation-mediated toxicity

(2012) Pradeep Dewapriya et al.   NEUROTOXICOLOGY

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One