5-HT6 Receptor Agonist and Antagonist Against β-Amyloid-Peptide-Induced Neurotoxicity in PC-12 Cells

Molecular and cellular pathophysiology of preclinical Alzheimer’s disease

(2016) Elliott J. Mufson et al.   BEHAVIOURAL BRAIN RESEARCH

Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo

(2016) Jonathan R. Fisher et al.   Molecular Neurodegeneration

5-HT6 Receptor Antagonists: Potential Efficacy for the Treatment of Cognitive Impairment in Schizophrenia

(2015) Natasja de Bruin et al.   CURRENT PHARMACEUTICAL DESIGN

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Diverse Molecular Targets for Therapeutic Strategies in Alzheimer's Disease

(2014) Sun-Ho Han et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Safety and efficacy of idalopirdine, a 5-HT 6 receptor antagonist, in patients with moderate Alzheimer's disease (LADDER): a randomised, double-blind, placebo-controlled phase 2 trial

(2014) David Wilkinson et al.   LANCET NEUROLOGY

5-HT6 receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms

(2012) S Woods et al.   BRITISH JOURNAL OF PHARMACOLOGY

Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress

(2012) Andleeb Khan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Protective Effect of Isorhynchophylline Against β-Amyloid-Induced Neurotoxicity in PC12 Cells

(2011) Yan-Fang Xian et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Serotonin signaling is associated with lower amyloid-  levels and plaques in transgenic mice and humans

(2011) J. R. Cirrito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by ß-amyloid peptide

(2010) C Kurz et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-HT6 Receptor Antagonists as Potential Therapeutics for Cognitive Impairment

(2010) Gerard Rosse et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats

(2010) Jorn Arnt et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Disease-Modifying Approach to the Treatment of Alzheimerʼs Disease

(2009) Francesco Panza et al.   DRUGS & AGING

An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function

(2008) Kevin C.F. Fone   NEUROPHARMACOLOGY