Evolutionary driving forces of A‐to‐I editing in metazoans

A-to-I RNA editing in honeybees shows signals of adaptation and convergent evolution

(2021) Yuange Duan et al.   iScience

A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing

(2020) Pedro Henrique Costa Cruz et al.   RNA

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

(2020) Patricia Deng et al.   Nature Communications

ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility

(2020) Elizabeth Snyder et al.   Scientific Reports

Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development

(2020) Suba Rajendren et al.   GENOME RESEARCH

Illuminating spatial A-to-I RNA editing signatures within the Drosophila brain

(2019) Anne L. Sapiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Investigation and Functional Analysis of Sus scrofa RNA Editing Sites across Eleven Tissues

(2019) Zishuai Wang et al.   Genes

RNA editing is abundant and correlates with task performance in a social bumblebee

(2019) Hagit T. Porath et al.   Nature Communications

A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing

(2019) Konstantin Licht et al.   GENOME RESEARCH

RNA editing in the forefront of epitranscriptomics and human health

(2019) Theodoulakis Christofi et al.   Journal of Translational Medicine

The preponderance of nonsynonymous A-to-I RNA editing in coleoids is nonadaptive

(2019) Daohan Jiang et al.   Nature Communications

A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer

(2018) Xinxin Peng et al.   CANCER CELL

A-to-I RNA editing — immune protector and transcriptome diversifier

(2018) Eli Eisenberg et al.   NATURE REVIEWS GENETICS

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

(2017) Yumeng Wang et al.   GENOME RESEARCH

Linkage of A-to-I RNA Editing in Metazoans and the Impact on Genome Evolution

(2017) Yuange Duan et al.   MOLECULAR BIOLOGY AND EVOLUTION

A-to-I RNA Editing in the Earliest-Diverging Eumetazoan Phyla

(2017) Hagit T. Porath et al.   MOLECULAR BIOLOGY AND EVOLUTION

Dynamic landscape and regulation of RNA editing in mammals

(2017) Meng How Tan et al.   NATURE

Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets

(2017) Yishay Pinto et al.   NUCLEIC ACIDS RESEARCH

Regulation of gene expression and RNA editing in Drosophila adapting to divergent microclimates

(2017) Arielle L. Yablonovitch et al.   Nature Communications

Dynamic hyper-editing underlies temperature adaptation in Drosophila

(2017) Ilana Buchumenski et al.   PLoS Genetics

Evolutionary analysis reveals regulatory and functional landscape of coding and non-coding RNA editing

(2017) Rui Zhang et al.   PLoS Genetics

Adaptation of A-to-I RNA editing in Drosophila

(2017) Yuange Duan et al.   PLoS Genetics

The evolution and adaptation of A-to-I RNA editing

(2017) Arielle L. Yablonovitch et al.   PLoS Genetics

A-to-I RNA editing promotes developmental stage–specific gene and lncRNA expression

(2016) Boaz Goldstein et al.   GENOME RESEARCH

Rapid and dynamic transcriptome regulation by RNA editing and RNA modifications

(2016) Konstantin Licht et al.   JOURNAL OF CELL BIOLOGY

Identification of human RNA editing sites: A historical perspective

(2016) Gokul Ramaswami et al.   METHODS

Evolution by gene loss

(2016) Ricard Albalat et al.   NATURE REVIEWS GENETICS

REDIportal: a comprehensive database of A-to-I RNA editing events in humans

(2016) Ernesto Picardi et al.   NUCLEIC ACIDS RESEARCH

The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection

(2016) Yao Yu et al.   PLoS Genetics

Dynamic response of RNA editing to temperature in Drosophila

(2015) Leila E Rieder et al.   BMC BIOLOGY

The origin of the ADAR gene family and animal RNA editing

(2015) Laura F Grice et al.   BMC EVOLUTIONARY BIOLOGY

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

(2015) Leng Han et al.   CANCER CELL

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

The emerging role of RNA editing in plasticity

(2015) J. J. C. Rosenthal   JOURNAL OF EXPERIMENTAL BIOLOGY

A-to-I editing of coding and non-coding RNAs by ADARs

(2015) Kazuko Nishikura   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-wide identification and characterization of tissue-specific RNA editing events inD. melanogasterand their potential role in regulating alternative splicing

(2015) Alborz Mazloomian et al.   RNA Biology

Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease

(2015) Khen Khermesh et al.   RNA

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

Genetic mapping uncovers cis-regulatory landscape of RNA editing

(2015) Gokul Ramaswami et al.   Nature Communications

Profiling RNA editing in human tissues: towards the inosinome Atlas

(2015) Ernesto Picardi et al.   Scientific Reports

Cis Regulatory Effects on A-to-I RNA Editing in Related Drosophila Species

(2015) Anne L. Sapiro et al.   Cell Reports

Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors

(2015) Nurit Paz-Yaacov et al.   Cell Reports

Genetic Determinants of RNA Editing Levels of ADAR Targets in Drosophila melanogaster

(2015) Yerbol Z. Kurmangaliyev et al.   G3-Genes Genomes Genetics

The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing

(2015) Shahar Alon et al.   eLife

A-to-I editing on tRNAs: Biochemical, biological and evolutionary implications

(2014) Adrian Gabriel Torres et al.   FEBS LETTERS

Profiling the RNA editomes of wild-typeC. elegansand ADAR mutants

(2014) Han-Qing Zhao et al.   GENOME RESEARCH

A biochemical landscape of A-to-I RNA editing in the human brain transcriptome

(2014) M. Sakurai et al.   GENOME RESEARCH

In Search of Beneficial Coding RNA Editing

(2014) Guixia Xu et al.   MOLECULAR BIOLOGY AND EVOLUTION

Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease

(2014) Inna Gaisler-Salomon et al.   NEUROBIOLOGY OF AGING

Human coding RNA editing is generally nonadaptive

(2014) G. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior

(2014) Qiye Li et al.   Nature Communications

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

The dsRBP and Inactive Editor ADR-1 Utilizes dsRNA Binding to Regulate A-to-I RNA Editing across the C. elegans Transcriptome

(2014) Michael C. Washburn et al.   Cell Reports

RNA Editome in Rhesus Macaque Shaped by Purifying Selection

(2014) Jia-Yu Chen et al.   PLoS Genetics

Mammalian conserved ADAR targets comprise only a small fragment of the human editosome

(2014) Yishay Pinto et al.   GENOME BIOLOGY

The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients

(2013) Takenari Yamashita et al.   BRAIN RESEARCH

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

(2013) L. Bazak et al.   GENOME RESEARCH

A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma

(2013) Tim Hon Man Chan et al.   GUT

Widespread splicing changes in human brain development and aging

(2013) P. Mazin et al.   Molecular Systems Biology

Identifying RNA editing sites using RNA sequencing data alone

(2013) Gokul Ramaswami et al.   NATURE METHODS

Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila

(2013) Georges St Laurent et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RADAR: a rigorously annotated database of A-to-I RNA editing

(2013) Gokul Ramaswami et al.   NUCLEIC ACIDS RESEARCH

Neofunctionalization of young duplicate genes in Drosophila

(2013) R. Assis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic identification of edited microRNAs in the human brain

(2012) S. Alon et al.   GENOME RESEARCH

Adar is essential for optimal presynaptic function

(2012) Carolina Maldonado et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Nascent-Seq Indicates Widespread Cotranscriptional RNA Editing in Drosophila

(2012) Joseph Rodriguez et al.   MOLECULAR CELL

Comparative RNA editing in autistic and neurotypical cerebella

(2012) A Eran et al.   MOLECULAR PSYCHIATRY

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome

(2012) Zhiyu Peng et al.   NATURE BIOTECHNOLOGY

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

RNA Editing Underlies Temperature Adaptation in K+ Channels from Polar Octopuses

(2012) S. Garrett et al.   SCIENCE

Serotonin 2c receptor RNA editing in major depression and suicide

(2012) Rebecca Lyddon et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Auto-regulatory RNA editing fine-tunes mRNA re-coding and complex behaviour in Drosophila

(2012) Yiannis A. Savva et al.   Nature Communications

MDA5 Detects the Double-Stranded RNA Replicative Form in Picornavirus-Infected Cells

(2012) Qian Feng et al.   Cell Reports

The ADAR protein family

(2012) Yiannis A Savva et al.   GENOME BIOLOGY

High levels of RNA-editing site conservation amongst 15 laboratory mouse strains

(2012) Petr Daneck et al.   GENOME BIOLOGY

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Engineered Alterations in RNA Editing Modulate Complex Behavior inDrosophila

(2010) James E. C. Jepson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The developmental transcriptome of Drosophila melanogaster

(2010) Brenton R. Graveley et al.   NATURE

RNA editing: a driving force for adaptive evolution?

(2009) Willemijn M. Gommans et al.   BIOESSAYS

Adenosine deamination in human transcripts generates novel microRNA binding sites

(2009) Glen M. Borchert et al.   HUMAN MOLECULAR GENETICS

Origins and evolution of ADAR-mediated RNA editing

(2009) Yongfeng Jin et al.   IUBMB LIFE

Effective population size and patterns of molecular evolution and variation

(2009) Brian Charlesworth   NATURE REVIEWS GENETICS

Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

(2009) J. B. Li et al.   SCIENCE