Iron-sulfur flavoenzymes: the added value of making the most ancient redox cofactors and the versatile flavins work together

Universal free-energy landscape produces efficient and reversible electron bifurcation

(2020) J. L. Yuly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distribution, Evolution, Catalytic Mechanism, and Physiological Functions of the Flavin-Based Electron-Bifurcating NADH-Dependent Reduced Ferredoxin: NADP+ Oxidoreductase

(2019) Jiyu Liang et al.   Frontiers in Microbiology

Identification of a Formate-Dependent Uric Acid Degradation Pathway in Escherichia coli

(2019) Yumi Iwadate et al.   JOURNAL OF BACTERIOLOGY

Mammalian Respiratory Complex I Through the Lens of Cryo-EM

(2019) Ahmed-Noor A. Agip et al.   Annual Review of Biophysics

Cryo-EM Structures of Azospirillum brasilense Glutamate Synthase in Its Oligomeric Assemblies

(2019) Paolo Swuec et al.   JOURNAL OF MOLECULAR BIOLOGY

A modeling and simulation perspective on the mechanism and function of respiratory complex I

(2018) Outi Haapanen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Global collective motions in the mammalian and bacterial respiratory complex I

(2018) Andrea Di Luca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

H/D exchange mass spectrometry and statistical coupling analysis reveal a role for allostery in a ferredoxin-dependent bifurcating transhydrogenase catalytic cycle

(2018) Luke Berry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Flavin-Based Electron Bifurcation, A New Mechanism of Biological Energy Coupling

(2018) Wolfgang Buckel et al.   CHEMICAL REVIEWS

Photoenzymes and Related Topics: An Update

(2018) Lars Olof Björn   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Electron Bifurcation and Confurcation in Methanogenesis and Reverse Methanogenesis

(2018) Zhen Yan et al.   Frontiers in Microbiology

On the Natural History of Flavin-Based Electron Bifurcation

(2018) Frauke Baymann et al.   Frontiers in Microbiology

Flavin-Based Electron Bifurcation, Ferredoxin, Flavodoxin, and Anaerobic Respiration With Protons (Ech) or NAD+ (Rnf) as Electron Acceptors: A Historical Review

(2018) Wolfgang Buckel et al.   Frontiers in Microbiology

A new era for electron bifurcation

(2018) John W Peters et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Origin and Evolution of Flavin-Based Electron Bifurcating Enzymes

(2018) Saroj Poudel et al.   Frontiers in Microbiology

Two functionally distinct NADP + -dependent ferredoxin oxidoreductases maintain the primary redox balance of Pyrococcus furiosus

(2017) Diep M. N. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryptochrome photoreceptors in green algae: Unexpected versatility of mechanisms and functions

(2017) Tilman Kottke et al.   JOURNAL OF PLANT PHYSIOLOGY

Mechanistic insights into energy conservation by flavin-based electron bifurcation

(2017) Carolyn E Lubner et al.   Nature Chemical Biology

Crystal Structures of Bacterial (6-4) Photolyase Mutants with Impaired DNA Repair Activity

(2017) Fan Zhang et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Evolution of the acceptor side of photosystem I: ferredoxin, flavodoxin, and ferredoxin-NADP+ oxidoreductase

(2017) Juan José Pierella Karlusich et al.   PHOTOSYNTHESIS RESEARCH

Flavins as Covalent Catalysts: New Mechanisms Emerge

(2017) Valentina Piano et al.   TRENDS IN BIOCHEMICAL SCIENCES

The multitude of iron–sulfur clusters in respiratory complex I

(2016) Emmanuel Gnandt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Structure and function of mitochondrial complex I

(2016) Christophe Wirth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Electron bifurcation

(2016) John W Peters et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Sweating the assets of flavin cofactors: new insight of chemical versatility from knowledge of structure and mechanism

(2016) David Leys et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Ligand binding and conformational dynamics in a flavin-based electron-bifurcating enzyme complex revealed by Hydrogen-Deuterium Exchange Mass Spectrometry

(2016) Julius K. Demmer et al.   FEBS LETTERS

Insights into Flavin-based Electron Bifurcation via the NADH-dependent Reduced Ferredoxin:NADP Oxidoreductase Structure

(2015) Julius K. Demmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Key Amino Acids in the Bacterial (6-4) Photolyase PhrB from Agrobacterium fabrum

(2015) Dominik Graf et al.   PLoS One

Electron flow through biological molecules: does hole hopping protect proteins from oxidative damage?

(2015) Jay R. Winkler et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Mechanistic insight from the crystal structure of mitochondrial complex I

(2015) V. Zickermann et al.   SCIENCE

On the mechanism of respiratory complex I

(2014) Thorsten Friedrich   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Defining a direction: Electron transfer and catalysis in Escherichia coli complex II enzymes

(2013) Elena Maklashina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Prokaryotic FAD Synthetase Family: A Potential Drug Target

(2013) Ana Serrano et al.   CURRENT PHARMACEUTICAL DESIGN

Biosynthesis of Flavin Cofactors in Man: Implications in Health and Disease

(2013) Maria Barile et al.   CURRENT PHARMACEUTICAL DESIGN

Crystal structure of a prokaryotic (6-4) photolyase with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophore

(2013) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CryB from Rhodobacter sphaeroides: a unique class of cryptochromes with new cofactors

(2012) Yann Geisselbrecht et al.   EMBO REPORTS

Flavoenzymes: Versatile catalysts in biosynthetic pathways

(2012) Christopher T. Walsh et al.   NATURAL PRODUCT REPORTS

The enigmatic reaction of flavins with oxygen

(2012) Pimchai Chaiyen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Presenting your structures: theCCP4mgmolecular-graphics software

(2011) S. McNicholas et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Iron–sulphur clusters in nucleic acid processing enzymes

(2011) Malcolm F White et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein Conformational Gating of Enzymatic Activity in Xanthine Oxidoreductase

(2011) Hiroshi Ishikita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Guidelines for tunneling in enzymes

(2010) Christopher C. Moser et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase

(2010) Ludovic Sauguet et al.   PLoS One

Energy matters: Mitochondrial proteomics for biomedicine

(2010) Elisabetta Gianazza et al.   PROTEOMICS

Mammalian xanthine oxidoreductase - mechanism of transition from xanthine dehydrogenase to xanthine oxidase

(2008) Tomoko Nishino et al.   FEBS Journal

Structure–function studies of glutamate synthases: A class of self-regulated iron-sulfur flavoenzymes essential for nitrogen assimilation

(2008) Maria Antonietta Vanoni et al.   IUBMB LIFE

The Subnanometer Resolution Structure of the Glutamate Synthase 1.2-MDa Hexamer by Cryoelectron Microscopy and Its Oligomerization Behavior in Solution

(2008) Magali Cottevieille et al.   JOURNAL OF BIOLOGICAL CHEMISTRY