Hydrogen peroxide (H2O2) mediated activation of mTORC2 increases intracellular Na+ concentration in the renal medullary thick ascending limb of Henle

Nox4‐mTORC1 connection in salt‐induced hypertension and kidney injury in Dahl S rats

(2020) Vikash Kumar et al.   FASEB JOURNAL

NOX4/H 2 O 2 /mTORC1 Pathway in Salt-Induced Hypertension and Kidney Injury

(2020) Vikash Kumar et al.   HYPERTENSION

Time course effects of methotrexate on renal handling of water and electrolytes in rats. Role of aquaporin-2 and Na-K-2Cl-cotransporter

(2019) María Julia Severin et al.   TOXICOLOGY LETTERS

Therapeutic Suppression of mTOR (Mammalian Target of Rapamycin) Signaling Prevents and Reverses Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats

(2018) Vikash Kumar et al.   HYPERTENSION

mTORC1 Overactivation as a Key Aging Factor in the Progression to Type 2 Diabetes Mellitus

(2018) Carlos Guillén et al.   Frontiers in Endocrinology

Inhibition of Mammalian Target of Rapamycin Complex 1 Attenuates Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive RatsNovelty and Significance

(2017) Vikash Kumar et al.   HYPERTENSION

mTORC2 critically regulates renal potassium handling

(2016) Florian Grahammer et al.   JOURNAL OF CLINICAL INVESTIGATION

ROS and ROS-Mediated Cellular Signaling

(2016) Jixiang Zhang et al.   Oxidative Medicine and Cellular Longevity

Hydrogen Peroxide and Sodium Transport in the Lung and Kidney

(2016) V. Shlyonsky et al.   Biomed Research International

Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats

(2015) Allen W. Cowley et al.   HYPERTENSION

Regulation of the epithelial Na+channel by the mTORC2/SGK1 pathway

(2015) Florian Lang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor

(2014) Yukio Nisimoto et al.   BIOCHEMISTRY

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity

(2014) Catherine E. Gleason et al.   JOURNAL OF CLINICAL INVESTIGATION

Redox-mediated signal transduction by cardiovascular Nox NADPH oxidases

(2014) Ralf P. Brandes et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Making new contacts: the mTOR network in metabolism and signalling crosstalk

(2014) Mitsugu Shimobayashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Potential role of Akt signaling in chronic kidney disease

(2014) A. Lan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Hydrogen peroxide signaling in vascular endothelial cells

(2014) Rosa Bretón-Romero et al.   Redox Biology

NADPH Oxidases: A Perspective on Reactive Oxygen Species Production in Tumor Biology

(2013) Jennifer L. Meitzler et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct

(2013) Tengis S. Pavlov et al.   FASEB JOURNAL

Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4

(2012) Katherine J. Massey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1

(2012) Daria V. Ilatovskaya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

Role of H2O2 in hypertension, renin-angiotensin system activation and renal medullary disfunction caused by angiotensin II

(2012) T Sousa et al.   BRITISH JOURNAL OF PHARMACOLOGY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Mitochondrial proteomic analysis reveals deficiencies in oxygen utilization in medullary thick ascending limb of Henle in the Dahl salt-sensitive rat

(2012) Nadezhda N. Zheleznova et al.   PHYSIOLOGICAL GENOMICS

Large-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubule

(2011) Marina Feric et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Amino Acid Signaling in TOR Activation

(2011) Joungmok Kim et al.   Annual Review of Biochemistry

Hydrogen Peroxide Stimulates the Epithelial Sodium Channel through a Phosphatidylinositide 3-Kinase-dependent Pathway

(2011) He-Ping Ma   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation and Identification of Na,K-ATPase α1 Subunit Phosphorylation in Rat Parotid Acinar Cells

(2010) Stephen P. Soltoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR Complex-2 Activates ENaC by Phosphorylating SGK1

(2010) M. Lu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cells

(2010) R. Gunaratne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation

(2009) Mahdieh Sadidi et al.   BIOCHIMIE

Kinetic Studies on Enzyme-Catalyzed Reactions: Oxidation of Glucose, Decomposition of Hydrogen Peroxide and Their Combination

(2009) Zhimin Tao et al.   BIOPHYSICAL JOURNAL

cAMP Stimulates Apical Exocytosis of the Renal Na+-K+-2Cl−Cotransporter NKCC2 in the Thick Ascending Limb

(2009) Paulo S. Caceres et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease

(2009) W. Lieberthal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH Oxidases, Reactive Oxygen Species, and Hypertension: Clinical implications and therapeutic possibilities

(2008) T. M. Paravicini et al.   DIABETES CARE

Renal Medullary Oxidative Stress, Pressure-Natriuresis, and Hypertension

(2008) Allen W. Cowley   HYPERTENSION