Associations of Arachidonic Acid Synthesis with Cardiovascular Risk Factors and Relation to Ischemic Heart Disease and Stroke: A Univariable and Multivariable Mendelian Randomization Study

The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease

(2021) Marita Kalaoja et al.   Obesity

Use of Multivariable Mendelian Randomization to Address Biases Due to Competing Risk Before Recruitment

(2021) C. M. Schooling et al.   Frontiers in Genetics

The associations of plasma phospholipid arachidonic acid with cardiovascular diseases: A Mendelian randomization study

(2021) Ting Zhang et al.   EBioMedicine

Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study

(2020) Minna K. Karjalainen et al.   ATHEROSCLEROSIS

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

(2020) Tom G. Richardson et al.   PLOS MEDICINE

Roles for circulating polyunsaturated fatty acids in ischemic stroke and modifiable factors: a Mendelian randomization study

(2020) Tonghui Yuan et al.   Nutrition Journal

Circulating Lipoprotein Lipids, Apolipoproteins and Ischemic Stroke

(2020) Shuai Yuan et al.   ANNALS OF NEUROLOGY

Effect measure modification conceptualized using selection diagrams as medication by mechanisms of varying population-level relevance

(2019) P. Lopez et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Intake of arachidonic acid-containing lipids in adult humans: dietary surveys and clinical trials

(2019) Hiroshi Kawashima   Lipids in Health and Disease

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

(2019) Eeva Sliz et al.   JOURNAL OF MEDICAL GENETICS

Association of genetic variants related to plasma fatty acids with type 2 diabetes mellitus and glycaemic traits: a Mendelian randomisation study

(2019) Shuai Yuan et al.   DIABETOLOGIA

Plasma Phospholipid Fatty Acids, FADS1 and Risk of 15 Cardiovascular Diseases: A Mendelian Randomisation Study

(2019) Shuai Yuan et al.   Nutrients

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

(2018) Masahiro Kanai et al.   NATURE GENETICS

Arachidonic acid supplementation modulates blood and skeletal muscle lipid profile with no effect on basal inflammation in resistance exercise trained men

(2018) James F. Markworth et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks

(2018) Theingi Aung et al.   JAMA Cardiology

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

(2018) Loic Yengo et al.   HUMAN MOLECULAR GENETICS

Genomic atlas of the human plasma proteome

(2018) Benjamin B. Sun et al.   NATURE

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

(2018) Evangelos Evangelou et al.   NATURE GENETICS

Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia

(2018) Serena Tucci et al.   SCIENCE

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

(2018) Symen Ligthart et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

(2018) Eleanor Sanderson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

(2018) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interpreting findings from Mendelian randomization using the MR-Egger method

(2017) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy

(2017) Jessica M. B. Rees et al.   STATISTICS IN MEDICINE

Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic

(2016) Jack Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

(2015) Paul S. de Vries et al.   HUMAN MOLECULAR GENETICS

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Genome-Wide Association Study of Plasma N6 Polyunsaturated Fatty Acids Within the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

(2014) W. Guan et al.   Circulation-Cardiovascular Genetics

Genetic Determinants of Circulating Interleukin-1 Receptor Antagonist Levels and Their Association With Glycemic Traits

(2014) C. Herder et al.   DIABETES

Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome

(2014) S. Burgess   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease

(2012) Weihong Tang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

(2012)   LANCET

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

(2012)   LANCET

Effects of Dalcetrapib in Patients with a Recent Acute Coronary Syndrome

(2012) Gregory G. Schwartz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apolipoprotein A-I, apolipoprotein B, and apolipoprotein B/apolipoprotein A-I ratio: Reference intervals compared with values in different pathophysiological conditions from the FINRISK 2007 study

(2011) Jaana Leiviskä et al.   CLINICA CHIMICA ACTA

Supplementation of arachidonic acid-enriched oil increases arachidonic acid contents in plasma phospholipids, but does not increase their metabolites and clinical parameters in Japanese healthy elderly individuals: a randomized controlled study

(2011) Saki Kakutani et al.   Lipids in Health and Disease

Serum n−6 fatty acids and lipoprotein subclasses in middle-aged men: the population-based cross-sectional ERA-JUMP Study

(2010) et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Association of serum n-6 and n-3 polyunsaturated fatty acids with lipids in 3 populations of middle-aged men

(2009) Kenneth R Motoyama et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Plasma fatty acid composition and incident heart failure in middle-aged adults: The Atherosclerosis Risk in Communities (ARIC) Study

(2008) Kazumasa Yamagishi et al.   AMERICAN HEART JOURNAL