Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase

Subgenomic RNA from Dengue Virus Type 2 Suppresses Replication of Dengue Virus Genomes and Interacts with Virus-Encoded NS3 and NS5 Proteins

(2020) Sai Wang et al.   ACS Infectious Diseases

A conformation-based intra-molecular initiation factor identified in the flavivirus RNA-dependent RNA polymerase

(2020) Jiqin Wu et al.   PLoS Pathogens

Identification of the viral RNA promoter stem loop A (SLA)-binding site on Zika virus polymerase NS5

(2020) Paul J. Bujalowski et al.   Scientific Reports

Zika virus non‐structural protein 5 residue R681 is critical for dimer formation and enzymatic activity

(2019) Wuan‐Geok Saw et al.   FEBS LETTERS

Supramolecular arrangement of the full-length Zika virus NS5

(2019) Diego S. Ferrero et al.   PLoS Pathogens

Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses

(2019) Anna Dubankova et al.   ANTIVIRAL RESEARCH

Retroviral RNA Dimerization: From Structure to Functions

(2018) Noé Dubois et al.   Frontiers in Microbiology

Pervasive tertiary structure in the dengue virus RNA genome

(2018) Elizabeth A. Dethoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions between the Dengue Virus Polymerase NS5 and Stem-Loop A

(2017) Paul J. Bujalowski et al.   JOURNAL OF VIROLOGY

Structure and function of the Zika virus full-length NS5 protein

(2017) Baoyu Zhao et al.   Nature Communications

Crystal structure of full-lengthZika virusNS5 protein reveals a conformation similar toJapanese encephalitis virusNS5

(2017) Anup K. Upadhyay et al.   Acta Crystallographica Section F-Structural Biology Communications

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

(2016) Jonathan J. Miner et al.   CELL

Identification of a Conserved RNA-dependent RNA Polymerase (RdRp)-RNA Interface Required for Flaviviral Replication

(2016) Kenneth Hodge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives

(2016) Bruno Coutard et al.   JOURNAL OF VIROLOGY

Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface

(2016) Valerie J. Klema et al.   PLoS Pathogens

Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization

(2016) Zhong-Yu Liu et al.   eLife

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

(2015) Yongqian Zhao et al.   PLoS Pathogens

Substitution of NS5 N-terminal Domain of Dengue Virus Type 2 RNA with Type 4 Domain Caused Impaired Replication and Emergence of Adaptive Mutants with Enhanced Fitness

(2014) Tadahisa Teramoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of specific dengue virus 2′-O- and N7-methyltransferase assays for antiviral drug screening

(2013) K. Barral et al.   ANTIVIRAL RESEARCH

Crystal Structure of the Full-Length Japanese Encephalitis Virus NS5 Reveals a Conserved Methyltransferase-Polymerase Interface

(2013) Guoliang Lu et al.   PLoS Pathogens

Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome

(2012) Barbara Selisko et al.   PLoS Pathogens

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

Full-length Dengue Virus RNA-dependent RNA Polymerase-RNA/DNA Complexes

(2011) Michal R. Szymanski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The F1 Motif of Dengue Virus Polymerase NS5 Is Involved in Promoter-Dependent RNA Synthesis

(2011) N. G. Iglesias et al.   JOURNAL OF VIROLOGY

Functional RNA Elements in the Dengue Virus Genome

(2011) Leopoldo G. Gebhard et al.   Viruses-Basel

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

RNA Sequences and Structures Required for the Recruitment and Activity of the Dengue Virus Polymerase

(2010) Claudia V. Filomatori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C virus genomic RNA dimerization is mediated via a kissing complex intermediate

(2010) S. Shetty et al.   RNA

RNA-dependent RNA polymerases from Flaviviridae

(2009) Kyung H Choi et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

RNA elements within the 5' untranslated region of the West Nile virus genome are critical for RNA synthesis and virus replication

(2009) X. F. Li et al.   JOURNAL OF GENERAL VIROLOGY

A generic protocol for the expression and purification of recombinant RNA in Escherichia coli using a tRNA scaffold

(2009) Luc Ponchon et al.   Nature Protocols

The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure

(2009) M. Issur et al.   RNA

Structural and Functional Studies of the Promoter Element for Dengue Virus RNA Replication

(2008) M. F. Lodeiro et al.   JOURNAL OF VIROLOGY

Specific requirements for elements of the 5′ and 3′ terminal regions in flavivirus RNA synthesis and viral replication

(2008) Li Yu et al.   VIROLOGY