The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis

Loss of CD36 impairs hepatic insulin signaling by enhancing the interaction of PTP1B with IR

(2020) Ping Yang et al.   FASEB JOURNAL

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

(2020) Haiping Wang et al.   NATURE IMMUNOLOGY

Dual Inhibition of CDK4/6 and PI3K/AKT/mTOR Signaling Impairs Energy Metabolism in MPM Cancer Cells

(2020) Mara Bonelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hepatic cholesterol synthesis and lipoprotein levels impaired by dietary fructose and saturated fatty acids in mice: Insight on PCSK9 and CD36

(2020) Reyhan Nergiz-Unal et al.   NUTRITION

Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells

(2020) James Drury et al.   Frontiers in Oncology

Deoxyshikonin Inhibits Viability and Glycolysis by Suppressing the Akt/mTOR Pathway in Acute Myeloid Leukemia Cells

(2020) Huijuan Wu et al.   Frontiers in Oncology

HKDC1 promotes the tumorigenesis and glycolysis in lung adenocarcinoma via regulating AMPK/mTOR signaling pathway

(2020) Xinyu Wang et al.   Cancer Cell International

Role of the Scavenger Receptor CD36 in Accelerated Diabetic Atherosclerosis

(2020) Miquel Navas-Madroñal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-oncogene PTPN13 inactivation by hepatitis B virus X protein counteracts IGF2BP1 to promote hepatocellular carcinoma progression

(2020) Yongcong Yan et al.   ONCOGENE

SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism

(2020) Ashutosh Kumar et al.   eLife

CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway

(2019) Yun Li et al.   JOURNAL OF LIPID RESEARCH

CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway

(2019) Jiaomeng Pan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ER-residential Nogo-B accelerates NAFLD-associated HCC mediated by metabolic reprogramming of oxLDL lipophagy

(2019) Yuan Tian et al.   Nature Communications

Hypothalamic Fatty Acids and Ketone Bodies Sensing and Role of FAT/CD36 in the Regulation of Food Intake

(2019) Christelle Le Foll   Frontiers in Physiology

CD36 and lipid metabolism in the evolution of atherosclerosis

(2018) Lei Zhao et al.   BRITISH MEDICAL BULLETIN

Regulation of Insulin Receptor Pathway and Glucose Metabolism by CD36 Signaling

(2018) Dmitri Samovski et al.   DIABETES

CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis

(2018) Lei Zhao et al.   JOURNAL OF HEPATOLOGY

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

(2018) Dannielle DeWaal et al.   Nature Communications

Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2017 Edition)

(2018) Jian Zhou et al.   Liver Cancer

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway

(2018) Ping Yang et al.   CANCER LETTERS

Endothelial cell CD36 optimizes tissue fatty acid uptake

(2018) Ni-Huiping Son et al.   JOURNAL OF CLINICAL INVESTIGATION

Aberrant Metabolism in Hepatocellular Carcinoma Provides Diagnostic and Therapeutic Opportunities

(2018) Serena De Matteis et al.   Oxidative Medicine and Cellular Longevity

Inflammatory stress promotes the development of obesity-related chronic kidney disease via CD36 in mice

(2017) Ping Yang et al.   JOURNAL OF LIPID RESEARCH

Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival

(2017) Marin E. Nelson et al.   Nature Communications

Targeting metastasis-initiating cells through the fatty acid receptor CD36

(2016) Gloria Pascual et al.   NATURE

Non-invasive metabolic imaging of brain tumours in the era of precision medicine

(2016) Michelle M. Kim et al.   Nature Reviews Clinical Oncology

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice

(2016) Junjie Hu et al.   Scientific Reports

Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

(2015) Aritro Nath et al.   Scientific Reports

Structure-Function of CD36 and Importance of Fatty Acid Signal Transduction in Fat Metabolism

(2014) Marta Yanina Pepino et al.   Annual Review of Nutrition

Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim

(2014) Hye-Kyung Park et al.   BMC CANCER

Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells

(2014) Han Xie et al.   Cell Metabolism

Regulation of AMPK Activation by CD36 Links Fatty Acid Uptake to β-Oxidation

(2014) Dmitri Samovski et al.   DIABETES

Switching of Pyruvate Kinase Isoform L to M2 Promotes Metabolic Reprogramming in Hepatocarcinogenesis

(2014) Carmen Chak-Lui Wong et al.   PLoS One

The Apoptosis Repressor with a CARD Domain (ARC) Gene Is a Direct Hypoxia-Inducible Factor 1 Target Gene and Promotes Survival and Proliferation of VHL-Deficient Renal Cancer Cells

(2013) O. V. Razorenova et al.   MOLECULAR AND CELLULAR BIOLOGY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Specific immunization strategies against oxidized low-density lipoprotein: A novel way to reduce nonalcoholic steatohepatitis in mice

(2012) Veerle Bieghs et al.   HEPATOLOGY

PI3K/AKT/mTOR Pathway in Angiogenesis

(2011) Jayashree Karar et al.   Frontiers in Molecular Neuroscience

CD36 deficiency predisposing young children to fasting hypoglycemia

(2010) Hironori Nagasaka et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

GLUT1 as a therapeutic target in hepatocellular carcinoma

(2009) Thomas Amann et al.   EXPERT OPINION ON THERAPEUTIC TARGETS