Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis

Infection and atherosclerosis: TLR-dependent pathways

(2020) Bowei Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

HuR (Human Antigen R) Regulates the Contraction of Vascular Smooth Muscle and Maintains Blood Pressure

(2020) Shanshan Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Transcriptional suppression of AMPKα1 promotes breast cancer metastasis upon oncogene activation

(2020) Yong Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models

(2020) Shui-mei Sun et al.   ACTA PHARMACOLOGICA SINICA

Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy

(2019) David Mondaca-Ruff et al.   Frontiers in Pharmacology

Adipose HuR protects against diet-induced obesity and insulin resistance

(2019) Jingyuan Li et al.   Nature Communications

Inhibition of Caspase-2 Translation by the mRNA Binding Protein HuR: A Novel Path of Therapy Resistance in Colon Carcinoma Cells?

(2019) Eberhardt et al.   Cells

A Double Negative Feedback Loop between mTORC1 and AMPK Kinases Guarantees Precise Autophagy Induction upon Cellular Stress

(2019) Marianna Holczer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genetic Deletion of IL-19 (Interleukin-19) Exacerbates Atherogenesis inIl19−/−×Ldlr−/−Double Knockout Mice by Dysregulation of mRNA Stability Protein HuR (Human Antigen R)Highlights

(2018) Mitali Ray et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis

(2018) Yusuke Osonoi et al.   Autophagy

Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis

(2018) Mandy O J Grootaert et al.   CARDIOVASCULAR RESEARCH

The induced RNA-binding protein, HuR, targets 3′-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis

(2018) K. Ouhara et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Neuron-Specific HuR-Deficient Mice Spontaneously Develop Motor Neuron Disease

(2018) Kevin Sun et al.   JOURNAL OF IMMUNOLOGY

The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer

(2018) Yanqing Liu et al.   Molecular Cancer

Defective Autophagy in Atherosclerosis: To Die or to Senesce?

(2018) Mandy O. J. Grootaert et al.   Oxidative Medicine and Cellular Longevity

AMPK: Regulation of Metabolic Dynamics in the Context of Autophagy

(2018) Isaac Tamargo-Gómez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin enhances atherosclerotic plaque stability by inducing prolyl-4-hydroxylase α1 expression

(2018) Hongxuan Li et al.   JOURNAL OF HYPERTENSION

Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation

(2018) Eleni Christodoulou-Vafeiadou et al.   Frontiers in Immunology

Mouse models of atherosclerosis: a historical perspective and recent advances

(2017) Yee Ting Lee et al.   Lipids in Health and Disease

CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype

(2017) Shruti Lal et al.   MOLECULAR CANCER RESEARCH

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

(2017) Anne-Clemence Vion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1

(2017) Kotb Abdelmohsen et al.   RNA Biology

Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity

(2016) Yuan Zhang et al.   Autophagy

Vascular Smooth Muscle Cells in Atherosclerosis

(2016) Martin R. Bennett et al.   CIRCULATION RESEARCH

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

(2016) Michael A. Gimbrone et al.   CIRCULATION RESEARCH

mir-101-3p is a key regulator of tumor metabolism in triple negative breast cancer targeting AMPK

(2016) Peng Liu et al.   Oncotarget

Posttranslational control of HuR function

(2016) Ioannis Grammatikakis et al.   Wiley Interdisciplinary Reviews-RNA

Intact endothelial autophagy is required to maintain vascular lipid homeostasis

(2015) Kumiko Torisu et al.   AGING CELL

Hydrogen sulfide reduces serum triglyceride by activating liver autophagy via the AMPK-mTOR pathway

(2015) Li Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis

(2015) Mandy OJ Grootaert et al.   Autophagy

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

(2015) Kun Liu et al.   Autophagy

Autophagy and oxidative stress in cardiovascular diseases

(2015) Yu Mei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Autophagy in Vascular Disease

(2015) G. R. Y. De Meyer et al.   CIRCULATION RESEARCH

Role of vascular smooth muscle cell in the inflammation of atherosclerosis

(2014) Soyeon Lim et al.   BMB Reports

Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis

(2014) Sima Allahverdian et al.   CIRCULATION

Induction of Atherosclerosis in Mice and Hamsters Without Germline Genetic Engineering

(2014) Martin Mæng Bjørklund et al.   CIRCULATION RESEARCH

The effects of age and muscle contraction on AMPK activity and heterotrimer composition

(2014) Shalene E. Hardman et al.   EXPERIMENTAL GERONTOLOGY

G Protein-coupled Estrogen Receptor Protects from Atherosclerosis

(2014) Matthias R. Meyer et al.   Scientific Reports

Multiple Functions of the RNA-Binding Protein HuR in Cancer Progression, Treatment Responses and Prognosis

(2013) Jun Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy Links Inflammasomes to Atherosclerotic Progression

(2012) Babak Razani et al.   Cell Metabolism

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

(2012) Xianghai Liao et al.   Cell Metabolism

AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

(2011) Antero Salminen et al.   AGEING RESEARCH REVIEWS

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Adrenergic Regulation of AMP-activated Protein Kinase in Brown Adipose Tissuein Vivo

(2011) Thomas Pulinilkunnil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

AMPK in cardiovascular health and disease

(2010) Najeeb A Shirwany et al.   ACTA PHARMACOLOGICA SINICA

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia

(2010) Konstantinos J. Mavrakis et al.   NATURE CELL BIOLOGY