The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer

Vasohibin 2 reduces chemosensitivity to gemcitabine in pancreatic cancer cells via Jun proto-oncogene dependent transactivation of ribonucleotide reductase regulatory subunit M2

(2017) Min Tu et al.   Molecular Cancer

miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1

(2017) Yanqing Liu et al.   Molecular Cancer

Cardioprotective effect of miRNA-22 on hypoxia/reoxygenation induced cardiomyocyte injury in neonatal rats

(2016) Jian Yang et al.   GENE

Molecular mechanisms and clinical applications of miR-22 in regulating malignant progression in human cancer (Review)

(2016) Jingyu Wang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

RNA-binding protein HuR and the members of the miR-200 family play an unconventional role in the regulation ofc-JunmRNA

(2016) Giorgia Del Vecchio et al.   RNA

microRNA-22 attenuates myocardial ischemia-reperfusion injury via an anti-inflammatory mechanism in rats

(2016) Jian Yang et al.   Experimental and Therapeutic Medicine

miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4

(2016) Yanqing Liu et al.   Protein & Cell

miR-22 as a prognostic factor targets glucose transporter protein type 1 in breast cancer

(2015) Bo Chen et al.   CANCER LETTERS

MiR-22 regulates 5-FU sensitivity by inhibiting autophagy and promoting apoptosis in colorectal cancer cells

(2015) Honghe Zhang et al.   CANCER LETTERS

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

(2015) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-22 inhibits tumor growth and metastasis in gastric cancer by directly targeting MMP14 and Snail

(2015) Q-F Zuo et al.   Cell Death & Disease

MicroRNA-22 Gates Long-Term Heterosynaptic Plasticity in Aplysia through Presynaptic Regulation of CPEB and Downstream Targets

(2015) Ferdinando Fiumara et al.   Cell Reports

A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis

(2014) L.-M. Kong et al.   CANCER RESEARCH

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiple Functions of the RNA-Binding Protein HuR in Cancer Progression, Treatment Responses and Prognosis

(2013) Jun Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miRNA-22 suppresses colon cancer cell migration and invasion by inhibiting the expression of T-cell lymphoma invasion and metastasis 1 and matrix metalloproteinases 2 and 9

(2013) BO LI et al.   ONCOLOGY REPORTS

A Novel p53/microRNA-22/Cyr61 Axis in Synovial Cells Regulates Inflammation in Rheumatoid Arthritis

(2013) Jinpiao Lin et al.   Arthritis & Rheumatology

Versatility of RNA-Binding Proteins in Cancer

(2012) Laurence Wurth   COMPARATIVE AND FUNCTIONAL GENOMICS

Emerging Roles of MicroRNA-22 in Human Disease and Normal Physiology

(2012) J. Xiong   CURRENT MOLECULAR MEDICINE

MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells

(2012) Silvia Alvarez-Díaz et al.   HUMAN MOLECULAR GENETICS

Contribution of Behavioral Risk Factors and Obesity to Socioeconomic Differences in Colorectal Cancer Incidence

(2012) C. A. Doubeni et al.   JNCI-Journal of the National Cancer Institute

Clinical significance of miR-22 expression in patients with colorectal cancer

(2012) Guangjun Zhang et al.   MEDICAL ONCOLOGY

EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF -Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib

(2012) Ryan B. Corcoran et al.   Cancer Discovery

Tumor Suppressor miR-22 Determines p53-Dependent Cellular Fate through Post-transcriptional Regulation of p21

(2011) N. Tsuchiya et al.   CANCER RESEARCH

Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation

(2011) Nieves Embade et al.   HEPATOLOGY

Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells

(2011) Jian Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The RNA-Binding Protein HuR Promotes Glioma Growth and Treatment Resistance

(2011) N. Filippova et al.   MOLECULAR CANCER RESEARCH

MicroRNA-22 Regulates Hypoxia Signaling in Colon Cancer Cells

(2011) Munekazu Yamakuchi et al.   PLoS One

microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity

(2010) J Zhang et al.   BRITISH JOURNAL OF CANCER

HuR Knockdown Changes the Oncogenic Potential of Oral Cancer Cells

(2010) W. Kakuguchi et al.   MOLECULAR CANCER RESEARCH

Posttranscriptional regulation of cancer traits by HuR

(2010) Kotb Abdelmohsen et al.   Wiley Interdisciplinary Reviews-RNA

Annotation of mammalian primary microRNAs

(2009) Harpreet K Saini et al.   BMC GENOMICS

Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates

(2009) Brenda K. Edwards et al.   CANCER

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

The mRNA Binding Proteins HuR and Tristetraprolin Regulate Cyclooxygenase 2 Expression During Colon Carcinogenesis

(2009) Lisa E. Young et al.   GASTROENTEROLOGY

MicroRNAs in colorectal cancer: translation of molecular biology into clinical application

(2009) Ondrej Slaby et al.   Molecular Cancer

RNA-binding proteins in human genetic disease

(2008) Kiven E. Lukong et al.   TRENDS IN GENETICS