Insect-Specific Flavivirus Replication in Mammalian Cells Is Inhibited by Physiological Temperature and the Zinc-Finger Antiviral Protein

The dinucleotide composition of the Zika virus genome is shaped by conflicting evolutionary pressures in mammalian hosts and mosquito vectors

(2021) Jelke J. Fros et al.   PLOS BIOLOGY

Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein

(2020) Xiu Luo et al.   Cell Reports

CpG-Recoding in Zika Virus Genome Causes Host-Age-Dependent Attenuation of Infection With Protection Against Lethal Heterologous Challenge in Mice

(2020) Ivan Trus et al.   Frontiers in Immunology

NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo

(2020) Agathe M. G. Colmant et al.   PLoS Neglected Tropical Diseases

Antigenic Characterization of New Lineage II Insect-Specific Flaviviruses in Australian Mosquitoes and Identification of Host Restriction Factors

(2020) Jessica J. Harrison et al.   mSphere

Characterization of novel splice variants of zinc finger antiviral protein (ZAP)

(2019) Melody M. H. Li et al.   JOURNAL OF VIROLOGY

The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides

(2019) Valerie Odon et al.   NUCLEIC ACIDS RESEARCH

KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides

(2019) Mattia Ficarelli et al.   eLife

Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences

(2019) Jennifer L. Meagher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus

(2019) Jody Hobson-Peters et al.   Science Translational Medicine

Characterization of Three New Insect-Specific Flaviviruses: Their Relationship to the Mosquito-Borne Flavivirus Pathogens

(2018) Hilda Guzman et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Signatures of DNA Methylation across Insects Suggest Reduced DNA Methylation Levels in Holometabola

(2018) Panagiotis Provataris et al.   Genome Biology and Evolution

Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein

(2018) Hsin-Ping Chiu et al.   PLoS Pathogens

Restriction of Zika virus infection and transmission in Aedes aegypti mediated by an insect-specific flavivirus

(2018) Hannah Romo et al.   Emerging Microbes & Infections

Adaptation of Rabensburg virus (RBGV) to vertebrate hosts by experimental evolution

(2018) Kiet A. Ngo et al.   VIROLOGY

CG dinucleotide suppression enables antiviral defence targeting non-self RNA

(2017) Matthew A. Takata et al.   NATURE

Lower temperatures reduce type I interferon activity and promote alphaviral arthritis

(2017) Natalie A. Prow et al.   PLoS Pathogens

TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP)

(2017) Melody M. H. Li et al.   PLoS Pathogens

CpG and UpA dinucleotides in both coding and non-coding regions of echovirus 7 inhibit replication initiation post-entry

(2017) Jelke Jan Fros et al.   eLife

A New Clade of Insect-Specific Flaviviruses from Australian Anopheles Mosquitoes Displays Species-Specific Host Restriction

(2017) Agathe M. G. Colmant et al.   mSphere

Host Range Restriction of Insect-Specific Flaviviruses Occurs at Several Levels of the Viral Life Cycle

(2017) Sandra Junglen et al.   mSphere

Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells

(2017) Thisun B. H. Piyasena et al.   Scientific Reports

Commensal Viruses of Mosquitoes: Host Restriction, Transmission, and Interaction with Arboviral Pathogens

(2016) Roy A. Hall et al.   Evolutionary Bioinformatics

Elevation of CpG frequencies in influenza A genome attenuates pathogenicity but enhances host response to infection

(2016) Eleanor Gaunt et al.   eLife

Insect-Specific Flaviviruses: A Systematic Review of Their Discovery, Host Range, Mode of Transmission, Superinfection Exclusion Potential and Genomic Organization

(2015) Bradley Blitvich et al.   Viruses-Basel

The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition

(2015) John B. Moldovan et al.   PLoS Genetics

The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication

(2014) Nicky J. Atkinson et al.   NUCLEIC ACIDS RESEARCH

Novel flaviviruses from mosquitoes: Mosquito-specific evolutionary lineages within the phylogenetic group of mosquito-borne flaviviruses

(2014) Eili Huhtamo et al.   VIROLOGY

Modelling mutational and selection pressures on dinucleotides in eukaryotic phyla –selection against CpG and UpA in cytoplasmically expressed RNA and in RNA viruses

(2013) Peter Simmonds et al.   BMC GENOMICS

Characterization of a novel flavivirus isolated from Culex (Melanoconion) ocossa mosquitoes from Iquitos, Peru

(2013) J. Evangelista et al.   JOURNAL OF GENERAL VIROLOGY

The influence of viral RNA secondary structure on interactions with innate host cell defences

(2013) J. Witteveldt et al.   NUCLEIC ACIDS RESEARCH

Translational repression precedes and is required for ZAP-mediated mRNA decay

(2012) Yiping Zhu et al.   EMBO JOURNAL

Glycogen Synthase Kinase 3β (GSK3β) Modulates Antiviral Activity of Zinc-finger Antiviral Protein (ZAP)

(2012) Lin Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Classical Swine Fever Virus Npro Limits Type I Interferon Induction in Plasmacytoid Dendritic Cells by Interacting with Interferon Regulatory Factor 7

(2011) A. R. Fiebach et al.   JOURNAL OF VIROLOGY

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

(2011) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral Induction of the Zinc Finger Antiviral Protein Is IRF3-dependent but NF-κB-independent

(2010) Nan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A New Flavivirus and a New Vector: Characterization of a Novel Flavivirus Isolated from Uranotaenia Mosquitoes from a Tropical Rain Forest

(2009) S. Junglen et al.   JOURNAL OF VIROLOGY

Characterization of a Novel Flavivirus from Mosquitoes in Northern Europe That Is Related to Mosquito-Borne Flaviviruses of the Tropics

(2009) E. Huhtamo et al.   JOURNAL OF VIROLOGY

Virus-Host Coevolution: Common Patterns of Nucleotide Motif Usage in Flaviviridae and Their Hosts

(2009) Francisco P. Lobo et al.   PLoS One

T7 RNA polymerase-dependent and -independent systems for cDNA-based rescue of Rift Valley fever virus

(2008) M. Habjan et al.   JOURNAL OF GENERAL VIROLOGY

Arbovirus evolution in vivo is constrained by host alternation

(2008) L. L. Coffey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA