The influence of viral RNA secondary structure on interactions with innate host cell defences

Incoming RNA Virus Nucleocapsids Containing a 5′-Triphosphorylated Genome Activate RIG-I and Antiviral Signaling

(2013) Michaela Weber et al.   Cell Host & Microbe

MDA5 Localizes to Stress Granules, but This Localization Is Not Required for the Induction of Type I Interferon

(2013) M. A. Langereis et al.   JOURNAL OF VIROLOGY

Influence of genome-scale RNA structure disruption on the replication of murine norovirus—similar replication kinetics in cell culture but attenuation of viral fitness in vivo

(2013) Nora McFadden et al.   NUCLEIC ACIDS RESEARCH

A Virological View of Innate Immune Recognition

(2012) Akiko Iwasaki   Annual Review of Microbiology

Enterovirus 71 Disrupts Interferon Signaling by Reducing the Level of Interferon Receptor 1

(2012) J. Lu et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus (HCV) Induces Formation of Stress Granules Whose Proteins Regulate HCV RNA Replication and Virus Assembly and Egress

(2012) U. Garaigorta et al.   JOURNAL OF VIROLOGY

The 3′ Untranslated Regions of Influenza Genomic Sequences Are 5′PPP-Independent Ligands for RIG-I

(2012) William G. Davis et al.   PLoS One

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

(2012) Koji Onomoto et al.   PLoS One

Identification of multiple RIG-I-specific pathogen associated molecular patterns within the West Nile virus genome and antigenome

(2012) Jennifer German Shipley et al.   VIROLOGY

Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA

(2011) Eva Kowalinski et al.   CELL

Structural Insights into RNA Recognition by RIG-I

(2011) Dahai Luo et al.   CELL

Activation of RIG-I-like receptor signal transduction

(2011) Annie M. Bruns et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Innate Immune Responses in Human Monocyte-Derived Dendritic Cells Are Highly Dependent on the Size and the 5' Phosphorylation of RNA Molecules

(2011) M. Jiang et al.   JOURNAL OF IMMUNOLOGY

Failure to activate the IFN-β promoter by a paramyxovirus lacking an interferon antagonist

(2011) M.J. Killip et al.   VIROLOGY

RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications

(2011) Reneé C. Ireton et al.   Viruses-Basel

Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD

(2011) Lin Qu et al.   PLoS Pathogens

Norovirus Regulation of the Innate Immune Response and Apoptosis Occurs via the Product of the Alternative Open Reading Frame 4

(2011) Nora McFadden et al.   PLoS Pathogens

The Efficacy of siRNAs against Hepatitis C Virus Is Strongly Influenced by Structure and Target Site Accessibility

(2010) Selena M. Sagan et al.   CHEMISTRY & BIOLOGY

Regulation of innate immunity through RNA structure and the protein kinase PKR

(2010) Subba Rao Nallagatla et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

New Insights into the Role of RNase L in Innate Immunity

(2010) Arindam Chakrabarti et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Regulation of PKR by HCV IRES RNA: Importance of Domain II and NS5A

(2010) Rebecca Toroney et al.   JOURNAL OF MOLECULAR BIOLOGY

The Chase for the RIG-I Ligand—Recent Advances

(2010) Martin Schlee et al.   MOLECULAR THERAPY

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

(2010) Yanli Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Heterocellular induction of interferon by negative-sense RNA viruses

(2010) S. Chen et al.   VIROLOGY

Structural and functional diversity of viral IRESes

(2009) Laurent Balvay et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence

(2009) Barbara Rehermann   JOURNAL OF CLINICAL INVESTIGATION

Influenza Viruses Control the Vertebrate Type I Interferon System: Factors, Mechanisms, and Consequences

(2009) Thorsten Wolff et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

(2009) D. Uzri et al.   JOURNAL OF VIROLOGY

Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection

(2009) A. Pichlmair et al.   JOURNAL OF VIROLOGY

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

(2009) A. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the Antiviral Kinase PKR and Viral Countermeasures

(2009) Bianca Dauber et al.   Viruses-Basel

A Highly Structured, Nuclease-Resistant, Noncoding RNA Produced by Flaviviruses Is Required for Pathogenicity

(2008) Gorben P. Pijlman et al.   Cell Host & Microbe

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

The RNA-activated Protein Kinase Enhances the Induction of Interferon-β and Apoptosis Mediated by Cytoplasmic RNA Sensors

(2008) Christopher S. McAllister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of a Conserved RNA Replication Element (cre) within the 3Dpol-Coding Sequence of Hepatoviruses

(2008) Y. Yang et al.   JOURNAL OF VIROLOGY

Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses

(2008) M. Davis et al.   JOURNAL OF VIROLOGY

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

(2008) Takeshi Saito et al.   NATURE

The impact of target site accessibility on the design of effective siRNAs

(2008) Hakim Tafer et al.   NATURE BIOTECHNOLOGY

Relevance of RNA structure for the activity of picornavirus IRES elements

(2008) Olga Fernández-Miragall et al.   VIRUS RESEARCH

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY