Polygenic Adaptation: Integrating Population Genetics and Gene Regulatory Networks

Polygenic adaptation: a unifying framework to understand positive selection

(2020) Neda Barghi et al.   NATURE REVIEWS GENETICS

Polygenic adaptation: From sweeps to subtle frequency shifts

(2019) Ilse Höllinger et al.   PLoS Genetics

Genetic redundancy fuels polygenic adaptation in Drosophila

(2019) Neda Barghi et al.   PLOS BIOLOGY

Artificial Gene Regulatory Networks—A Review

(2019) Sylvain Cussat-Blanc et al.   ARTIFICIAL LIFE

Trans Effects on Gene Expression Can Drive Omnigenic Inheritance

(2019) Xuanyao Liu et al.   CELL

Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

(2019) Mashaal Sohail et al.   eLife

Reduced signal for polygenic adaptation of height in UK Biobank

(2019) Jeremy J Berg et al.   eLife

Network Medicine in the Age of Biomedical Big Data

(2019) Abhijeet R. Sonawane et al.   Frontiers in Genetics

Gene Expression Modularity Reveals Footprints of Polygenic Adaptation in Theobroma cacao

(2019) Tuomas Hämälä et al.   MOLECULAR BIOLOGY AND EVOLUTION

Polygenic selection drives the evolution of convergent transcriptomic landscapes across continents within a Nearctic sister species complex

(2019) Clément Rougeux et al.   MOLECULAR ECOLOGY

Polygenic Adaptation to an Environmental Shift: Temporal Dynamics of Variation Under Gaussian Stabilizing Selection and Additive Effects on a Single Trait

(2019) Kevin R. Thornton   GENETICS

Gene networks and the evolution of plant morphology

(2018) Mainak Das Gupta et al.   CURRENT OPINION IN PLANT BIOLOGY

Detecting Polygenic Adaptation in Admixture Graphs

(2018) Fernando Racimo et al.   GENETICS

Tread Lightly Interpreting Polygenic Tests of Selection

(2018) John Novembre et al.   GENETICS

Detecting the genomic signal of polygenic adaptation and the role of epistasis in evolution

(2018) Katalin Csilléry et al.   MOLECULAR ECOLOGY

Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk

(2018) Jian Zhou et al.   NATURE GENETICS

Detecting Polygenic Adaptation in Admixture Graphs

(2018) Fernando Racimo et al.   GENETICS

Tread Lightly Interpreting Polygenic Tests of Selection

(2018) John Novembre et al.   GENETICS

Developmental Bias and Evolution: A Regulatory Network Perspective

(2018) Tobias Uller et al.   GENETICS

A Polygenic Genetic Architecture of Flowering Time in the Worldwide Arabidopsis thaliana Population

(2018) Yanjun Zan et al.   MOLECULAR BIOLOGY AND EVOLUTION

The causes of evolvability and their evolution

(2018) Joshua L. Payne et al.   NATURE REVIEWS GENETICS

Genetic architecture and selective sweeps after polygenic adaptation to distant trait optima

(2018) Markus G. Stetter et al.   PLoS Genetics

The Relationship between Selection, Network Connectivity, and Regulatory Variation within a Population of Capsella grandiflora

(2017) Emily B. Josephs et al.   Genome Biology and Evolution

Genetic architecture: the shape of the genetic contribution to human traits and disease

(2017) Nicholas J. Timpson et al.   NATURE REVIEWS GENETICS

Detecting gene subnetworks under selection in biological pathways

(2017) Alexandre Gouy et al.   NUCLEIC ACIDS RESEARCH

Exploring regulation in tissues with eQTL networks

(2017) Maud Fagny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The infinitesimal model: Definition, derivation, and implications

(2017) N.H. Barton et al.   THEORETICAL POPULATION BIOLOGY

Perspectives on Gene Regulatory Network Evolution

(2017) Marc S. Halfon   TRENDS IN GENETICS

Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity

(2017) Pierre Khoueiry et al.   eLife

Constrained vertebrate evolution by pleiotropic genes

(2017) Haiyang Hu et al.   Nature Ecology & Evolution

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

(2016) Huwenbo Shi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness

(2016) Leeat Keren et al.   CELL

The Footprint of Polygenic Adaptation on Stress-ResponsiveCis-Regulatory Divergence in theArabidopsis Genus

(2016) Fei He et al.   MOLECULAR BIOLOGY AND EVOLUTION

Open chromatin reveals the functional maize genome

(2016) Eli Rodgers-Melnick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent Positive Selection Has Acted on Genes Encoding Proteins with More Interactions within the Whole Human Interactome

(2015) Pierre Luisi et al.   Genome Biology and Evolution

Population genetic differentiation of height and body mass index across Europe

(2015) Matthew R Robinson et al.   NATURE GENETICS

The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease

(2014) Jessica F Brinkworth et al.   CURRENT OPINION IN IMMUNOLOGY

The Genetic Architecture Of Maize Height

(2014) Jason A. Peiffer et al.   GENETICS

Genome-wide signals of positive selection in human evolution

(2014) D. Enard et al.   GENOME RESEARCH

A Population Genetic Signal of Polygenic Adaptation

(2014) Jeremy J. Berg et al.   PLoS Genetics

Beyond GWASs: Illuminating the Dark Road from Association to Function

(2013) Stacey L. Edwards et al.   AMERICAN JOURNAL OF HUMAN GENETICS

WHY EPISTASIS IS IMPORTANT FOR SELECTION AND ADAPTATION

(2013) Thomas F. Hansen   EVOLUTION

Evidence for Polygenic Adaptation to Pathogens in the Human Genome

(2013) Josephine T. Daub et al.   MOLECULAR BIOLOGY AND EVOLUTION

Comparative Polygenic Analysis of Maximal Ethanol Accumulation Capacity and Tolerance to High Ethanol Levels of Cell Proliferation in Yeast

(2013) Thiago M. Pais et al.   PLoS Genetics

Genetic Architecture of Flowering-Time Variation inArabidopsis thaliana

(2011) Patrice A. Salomé et al.   GENETICS

Decoupling of differentiation between traits and their underlying genes in response to divergent selection

(2011) A Kremer et al.   HEREDITY

Impact of selection on genes involved in regulatory network: a modelling study

(2011) B. RHONÉ et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Systematic Detection of Polygenic cis-Regulatory Evolution

(2011) Hunter B. Fraser et al.   PLoS Genetics

The genetics of quantitative traits: challenges and prospects

(2009) Trudy F. C. Mackay et al.   NATURE REVIEWS GENETICS

Evolutionary Processes Acting on Candidate cis-Regulatory Regions in Humans Inferred from Patterns of Polymorphism and Divergence

(2009) Dara G. Torgerson et al.   PLoS Genetics

Selective Sweep at a Quantitative Trait Locus in the Presence of Background Genetic Variation

(2008) Luis-Miguel Chevin et al.   GENETICS