Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

(2019) Simon Haworth et al.   Nature Communications

Reduced signal for polygenic adaptation of height in UK Biobank

(2019) Jeremy J Berg et al.   eLife

Detecting Polygenic Adaptation in Admixture Graphs

(2018) Fernando Racimo et al.   GENETICS

Tread Lightly Interpreting Polygenic Tests of Selection

(2018) John Novembre et al.   GENETICS

Signatures of negative selection in the genetic architecture of human complex traits

(2018) Jian Zeng et al.   NATURE GENETICS

Mixed-model association for biobank-scale datasets

(2018) Po-Ru Loh et al.   NATURE GENETICS

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

(2018) Jeanne E. Savage et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

(2018) Mats Nagel et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Global genetic differentiation of complex traits shaped by natural selection in humans

(2018) Jing Guo et al.   Nature Communications

Detecting Polygenic Adaptation in Admixture Graphs

(2018) Fernando Racimo et al.   GENETICS

Tread Lightly Interpreting Polygenic Tests of Selection

(2018) John Novembre et al.   GENETICS

The genomic history of southeastern Europe

(2018) Iain Mathieson et al.   NATURE

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Negative selection in humans and fruit flies involves synergistic epistasis

(2017) Mashaal Sohail et al.   SCIENCE

Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure

(2016) Kevin J. Galinsky et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Detection of human adaptation during the past 2000 years

(2016) Yair Field et al.   SCIENCE

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Approximately independent linkage disequilibrium blocks in human populations

(2015) Tomaz Berisa et al.   BIOINFORMATICS

Genome-wide patterns of selection in 230 ancient Eurasians

(2015) Iain Mathieson et al.   NATURE

Massive migration from the steppe was a source for Indo-European languages in Europe

(2015) Wolfgang Haak et al.   NATURE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Population genetic differentiation of height and body mass index across Europe

(2015) Matthew R Robinson et al.   NATURE GENETICS

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

A Population Genetic Signal of Polygenic Adaptation

(2014) Jeremy J. Berg et al.   PLoS Genetics

Multilocus Genetic Risk Scores for Coronary Heart Disease Prediction

(2013) Andrea Ganna et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Evidence of widespread selection on standing variation in Europe at height-associated SNPs

(2012) Michael C Turchin et al.   NATURE GENETICS

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

(2009) Shaun M. Purcell et al.   NATURE

The Population Reference Sample, POPRES: A Resource for Population, Disease, and Pharmacological Genetics Research

(2008) Matthew R. Nelson et al.   AMERICAN JOURNAL OF HUMAN GENETICS