Polygenic Adaptation to an Environmental Shift: Temporal Dynamics of Variation Under Gaussian Stabilizing Selection and Additive Effects on a Single Trait

Polygenic adaptation: From sweeps to subtle frequency shifts

(2019) Ilse Höllinger et al.   PLoS Genetics

Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

(2019) Mashaal Sohail et al.   eLife

Reduced signal for polygenic adaptation of height in UK Biobank

(2019) Jeremy J Berg et al.   eLife

Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits

(2019) Mahul Chakraborty et al.   Nature Communications

The Effect of Strong Purifying Selection on Genetic Diversity

(2018) Ivana Cvijović et al.   GENETICS

A population genetic interpretation of GWAS findings for human quantitative traits

(2018) Yuval B. Simons et al.   PLOS BIOLOGY

The Effect of Strong Purifying Selection on Genetic Diversity

(2018) Ivana Cvijović et al.   GENETICS

Replicability of Introgression Under Linked, Polygenic Selection

(2018) Himani Sachdeva et al.   GENETICS

Efficient pedigree recording for fast population genetics simulation

(2018) Jerome Kelleher et al.   PLoS Computational Biology

Genetic architecture and selective sweeps after polygenic adaptation to distant trait optima

(2018) Markus G. Stetter et al.   PLoS Genetics

Rapid Adaptation of a Polygenic Trait After a Sudden Environmental Shift

(2017) Kavita Jain et al.   GENETICS

Modes of Rapid Polygenic Adaptation

(2017) Kavita Jain et al.   MOLECULAR BIOLOGY AND EVOLUTION

A Model of Compound Heterozygous, Loss-of-Function Alleles Is Broadly Consistent with Observations from Complex-Disease GWAS Datasets

(2017) Jaleal S. Sanjak et al.   PLoS Genetics

Rapid Adaptation of a Polygenic Trait After a Sudden Environmental Shift

(2017) Kavita Jain et al.   GENETICS

Discoal: flexible coalescent simulations with selection

(2016) Andrew D. Kern et al.   BIOINFORMATICS

Detection of human adaptation during the past 2000 years

(2016) Yair Field et al.   SCIENCE

Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes

(2016) Jerome Kelleher et al.   PLoS Computational Biology

S/HIC: Robust Identification of Soft and Hard Sweeps Using Machine Learning

(2016) Daniel R. Schrider et al.   PLoS Genetics

A Coalescent Model for a Sweep of a Unique Standing Variant

(2015) Jeremy J. Berg et al.   GENETICS

Soft Shoulders Ahead: Spurious Signatures of Soft and Partial Selective Sweeps Result from Linked Hard Sweeps

(2015) D. R. Schrider et al.   GENETICS

Response of Polygenic Traits Under Stabilizing Selection and Mutation When Loci Have Unequal Effects

(2015) K. Jain et al.   G3-Genes Genomes Genetics

Recent Selective Sweeps in North American Drosophila melanogaster Show Signatures of Soft Sweeps

(2015) Nandita R. Garud et al.   PLoS Genetics

A Coalescent Model for a Sweep of a Unique Standing Variant

(2015) Jeremy J. Berg et al.   GENETICS

Determinants of Mutation Rate Variation in the Human Germline

(2014) Laure Ségurel et al.   Annual Review of Genomics and Human Genetics

A C++ Template Library for Efficient Forward-Time Population Genetic Simulation of Large Populations

(2014) Kevin R. Thornton   GENETICS

Stability and Response of Polygenic Traits to Stabilizing Selection and Mutation

(2014) Harold P. de Vladar et al.   GENETICS

On Detecting Incomplete Soft or Hard Selective Sweeps Using Haplotype Structure

(2014) Anna Ferrer-Admetlla et al.   MOLECULAR BIOLOGY AND EVOLUTION

Dissecting complex traits using the Drosophila Synthetic Population Resource

(2014) Anthony D. Long et al.   TRENDS IN GENETICS

Genetic Dissection of the Drosophila melanogaster Female Head Transcriptome Reveals Widespread Allelic Heterogeneity

(2014) Elizabeth G. King et al.   PLoS Genetics

SweeD: Likelihood-Based Detection of Selective Sweeps in Thousands of Genomes

(2013) Pavlos Pavlidis et al.   MOLECULAR BIOLOGY AND EVOLUTION

Population genomics of rapid adaptation by soft selective sweeps

(2013) Philipp W. Messer et al.   TRENDS IN ECOLOGY & EVOLUTION

Properties and Modeling of GWAS when Complex Disease Risk Is Due to Non-Complementing, Deleterious Mutations in Genes of Large Effect

(2013) Kevin R. Thornton et al.   PLoS Genetics

Genetic Heterogeneity in Human Disease

(2010) Jon McClellan et al.   CELL

EVOLUTION OF THE GENOMIC RATE OF RECOMBINATION IN MAMMALS

(2008) Beth L. Dumont et al.   EVOLUTION

Selective Sweep at a Quantitative Trait Locus in the Presence of Background Genetic Variation

(2008) Luis-Miguel Chevin et al.   GENETICS

Cis-regulatory Variation Is Typically Polyallelic in Drosophila

(2008) J. D. Gruber et al.   GENETICS

An Approximate Bayesian Estimator Suggests Strong, Recurrent Selective Sweeps in Drosophila

(2008) Jeffrey D. Jensen et al.   PLoS Genetics