Therapeutic Gene Silencing Using Targeted Lipid Nanoparticles in Metastatic Ovarian Cancer

A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes

(2020) Srinivas Ramishetti et al.   ADVANCED MATERIALS

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo

(2019) Nidhi Jyotsana et al.   ANNALS OF HEMATOLOGY

CD44 Expression Predicts Prognosis of Ovarian Cancer Patients Through Promoting Epithelial-Mesenchymal Transition (EMT) by Regulating Snail, ZEB1, and Caveolin-1

(2019) Jiayi Zhou et al.   Frontiers in Oncology

In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation

(2019) Elena M. Smekalova et al.   Molecular Therapy-Nucleic Acids

Mesenchymal splice isoform of CD44 (CD44s) promotes EMT/invasion and imparts stem-like properties to ovarian cancer cells

(2018) Rahul Bhattacharya et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b

(2018) Neha N. Parayath et al.   NANO LETTERS

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma

(2018) Hsin-Yi Lee et al.   Oncotarget

Optimized delivery of siRNA into 3D tumor spheroid cultures in situ

(2018) R. G. Morgan et al.   Scientific Reports

3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs

(2018) Ana S. Nunes et al.   BIOTECHNOLOGY AND BIOENGINEERING

Systemic delivery of siRNA by aminated poly( α )glutamate for the treatment of solid tumors

(2017) Dina Polyak et al.   JOURNAL OF CONTROLLED RELEASE

Proteomic analysis of polyribosomes identifies splicing factors as potential regulators of translation during mitosis

(2017) Ranen Aviner et al.   NUCLEIC ACIDS RESEARCH

Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway

(2017) Weipeng Zhao et al.   MEDICAL SCIENCE MONITOR

RNA nanomedicines: the next generation drugs?

(2016) Manu Smriti Singh et al.   CURRENT OPINION IN BIOTECHNOLOGY

Intratracheal Administration of Hyaluronan-Cisplatin Conjugate Nanoparticles Significantly Attenuates Lung Cancer Growth in Mice

(2016) Susumu Ishiguro et al.   PHARMACEUTICAL RESEARCH

The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer

(2016) Ranjeeta Thapa et al.   Stem Cells International

Localized RNAi Therapeutics of Chemoresistant Grade IV Glioma Using Hyaluronan-Grafted Lipid-Based Nanoparticles

(2015) Zvi R. Cohen et al.   ACS Nano

In vivo tumor growth of high-grade serous ovarian cancer cell lines

(2015) Anirban K. Mitra et al.   GYNECOLOGIC ONCOLOGY

Eukaryotic initiation factor 3C silencing inhibits cell proliferation and promotes apoptosis in human glioma

(2015) JINMIN HAO et al.   ONCOLOGY REPORTS

Modulation of Drug Resistance in Ovarian Adenocarcinoma Using Chemotherapy Entrapped in Hyaluronan-Grafted Nanoparticle Clusters

(2014) Keren Cohen et al.   ACS Nano

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

(2014) James E. Dahlman et al.   Nature Nanotechnology

Ovarian Cancer Cell Line Panel (OCCP): Clinical Importance of In Vitro Morphological Subtypes

(2014) Corine M. Beaufort et al.   PLoS One

Silencing HoxA1 by Intraductal Injection of siRNA Lipidoid Nanoparticles Prevents Mammary Tumor Progression in Mice

(2014) A. Brock et al.   Science Translational Medicine

eIF3c: A potential therapeutic target for cancer

(2013) Rafi Emmanuel et al.   CANCER LETTERS

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

(2012) Muthusamy Jayaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Smart Nanocarrier Based on PEGylated Hyaluronic Acid for Cancer Therapy

(2011) Ki Young Choi et al.   ACS Nano

Modeling RNA interference in mammalian cells

(2011) Giulia Cuccato et al.   BMC Systems Biology

Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance

(2011) Ayesha B. Alvero et al.   CELL CYCLE

The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures

(2010) Nupura S. Bhise et al.   BIOMATERIALS

The Omentum: Anatomical, Metabolic, and Surgical Aspects

(2009) Danielle Collins et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors

(2008) S. Zhang et al.   CANCER RESEARCH