Mesenchymal splice isoform of CD44 (CD44s) promotes EMT/invasion and imparts stem-like properties to ovarian cancer cells

CD44 Expression Level and Isoform Contributes to Pancreatic Cancer Cell Plasticity, Invasiveness, and Response to Therapy

(2016) Shujie Zhao et al.   CLINICAL CANCER RESEARCH

Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy

(2016) Wanyin Chen et al.   Stem Cells International

Translational potential of cancer stem cells: A review of the detection of cancer stem cells and their roles in cancer recurrence and cancer treatment

(2015) Farhadul Islam et al.   EXPERIMENTAL CELL RESEARCH

Invasion of ovarian cancer cells is induced byPITX2-mediated activation of TGF-β and Activin-A

(2015) Moitri Basu et al.   Molecular Cancer

Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes

(2015) A Sveen et al.   ONCOGENE

Epithelial Splicing Regulatory Proteins 1 (ESRP1) and 2 (ESRP2) Suppress Cancer Cell Motility via Different Mechanisms

(2014) Hiroki Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ovarian cancer

(2014) Gordon C Jayson et al.   LANCET

Tackling the cancer stem cells — what challenges do they pose?

(2014) Diwakar R. Pattabiraman et al.   NATURE REVIEWS DRUG DISCOVERY

Combined epithelial-mesenchymal transition with cancer stem cell-like marker as predictors of recurrence after radical resection for gastric cancer

(2014) Gui-fang Xu et al.   World Journal of Surgical Oncology

Overview: Cellular plasticity, cancer stem cells and metastasis

(2013) Wael M. ElShamy et al.   CANCER LETTERS

Ovarian cancer stem cells: Molecular concepts and relevance as therapeutic targets

(2013) Nuzhat Ahmed et al.   MOLECULAR ASPECTS OF MEDICINE

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche

(2013) Andrea Flesken-Nikitin et al.   NATURE

Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases

(2013) J Ueda et al.   ONCOGENE

Hallmarks of alternative splicing in cancer

(2013) S Oltean et al.   ONCOGENE

CD44 Staining of Cancer Stem-Like Cells Is Influenced by Down-Regulation of CD44 Variant Isoforms and Up-Regulation of the Standard CD44 Isoform in the Population of Cells That Have Undergone Epithelial-to-Mesenchymal Transition

(2013) Adrian Biddle et al.   PLoS One

Ovarian cancer stem cells: Working towards the root of stemness

(2012) Rosemary Foster et al.   CANCER LETTERS

Expression of PITX2 Homeodomain Transcription Factor during Rat Gonadal Development in a Sexually Dimorphic Manner

(2012) Shyam Sundar Nandi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

ETS-1 Protein Regulates Vascular Endothelial Growth Factor-induced Matrix Metalloproteinase-9 and Matrix Metalloproteinase-13 Expression in Human Ovarian Carcinoma Cell Line SKOV-3

(2012) Sonali Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

(2012) Toshifumi Yae et al.   Nature Communications

Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance

(2011) Ayesha B. Alvero et al.   CELL CYCLE

CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

(2011) Rhonda L. Brown et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP

(2011) K Horiguchi et al.   ONCOGENE

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

(2011) Irina M. Shapiro et al.   PLoS Genetics

An ESRP-regulated splicing programme is abrogated during the epithelial–mesenchymal transition

(2010) Claude C Warzecha et al.   EMBO JOURNAL

The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events

(2010) Claude C. Warzecha et al.   RNA Biology

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Aldehyde Dehydrogenase as a Marker for Stem Cells

(2008) Jan Moreb   Current Stem Cell Research & Therapy