DDAH2 suppresses RLR-MAVS–mediated innate antiviral immunity by stimulating nitric oxide–activated, Drp1-induced mitochondrial fission
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
DDAH2 suppresses RLR-MAVS–mediated innate antiviral immunity by stimulating nitric oxide–activated, Drp1-induced mitochondrial fission
Authors
Keywords
-
Journal
Science Signaling
Volume 14, Issue 678, Pages eabc7931
Publisher
American Association for the Advancement of Science (AAAS)
Online
2021-04-14
DOI
10.1126/scisignal.abc7931
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3
- (2019) Xiaohan Ning et al. MOLECULAR CELL
- Mitochondrial fission requires DRP1 but not dynamins
- (2019) Tiago Branco Fonseca et al. NATURE
- DDAH1 and DDAH2 polymorphisms associate with asymmetrical dimethylarginine plasma levels in erectile dysfunction patients but not in healthy controls
- (2019) Guilhermo Brites-Anselmi et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor
- (2019) Julien Lefranc et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nebivolol ameliorated kidney damage in Zucker diabetic fatty rats by regulation of oxidative stress/NO pathway: comparison with captopril
- (2018) Yan Wang et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Regulation of MAVS activation through post-translational modifications
- (2018) Bingyu Liu et al. CURRENT OPINION IN IMMUNOLOGY
- Virus Infection Triggers MAVS Polymers of Distinct Molecular Weight
- (2018) Natalia Zamorano Cuervo et al. Viruses-Basel
- The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways
- (2017) Parimala R. Vajjhala et al. MOLECULAR IMMUNOLOGY
- Relationship between asymmetric dimethylarginine, nitrite and genetic polymorphisms: Impact on erectile dysfunction therapy
- (2017) Ana Maria Milanez Azevedo et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner
- (2017) Run Fang et al. PLoS Pathogens
- S-Nitrosylation of DRP1 Does Not Affect Enzymatic Activity and is Not Specific to Alzheimer's Disease
- (2017) Blaise Bossy et al. JOURNAL OF ALZHEIMERS DISEASE
- Dynamin-Related Protein 1 Promotes Mitochondrial Fission and Contributes to The Hippocampal Neuronal Cell Death Following Experimental Status Epilepticus
- (2016) Shang-Der Chen et al. CNS Neuroscience & Therapeutics
- The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination
- (2016) Bingyu Liu et al. NATURE IMMUNOLOGY
- Asymmetric Dimethylarginine Limits the Efficacy of Simvastatin Activating Endothelial Nitric Oxide Synthase
- (2016) Chiao‐Po Hsu et al. Journal of the American Heart Association
- Dimethylarginine Dimethylaminohydrolase 2 Regulates Nitric Oxide Synthesis and Hemodynamics and Determines Outcome in Polymicrobial Sepsis
- (2015) S. Lambden et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Histone H3 Threonine Phosphorylation Regulates Asymmetric Histone Inheritance in the Drosophila Male Germline
- (2015) Jing Xie et al. CELL
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
- (2015) S. Liu et al. SCIENCE
- Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins
- (2015) Chia-Yi Yu et al. PLoS Pathogens
- Pharmacology and Clinical Pharmacology of Methylarginines Used as Inhibitors of Nitric Oxide Synthases
- (2014) Anja Kittel et al. CURRENT PHARMACEUTICAL DESIGN
- Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates
- (2014) Delphine Goubau et al. NATURE
- Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence
- (2014) S.-J. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for the prion-like MAVS filaments in antiviral innate immunity
- (2014) Hui Xu et al. eLife
- Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats
- (2013) Len Verbeke et al. HEPATOLOGY
- Cytosolic Sensing of Viruses
- (2013) Delphine Goubau et al. IMMUNITY
- MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades
- (2013) Siqi Liu et al. eLife
- Nitric oxide release: Part II. Therapeutic applications
- (2012) Alexis W. Carpenter et al. CHEMICAL SOCIETY REVIEWS
- Nitric Oxide Increases Susceptibility of Toll-like Receptor-Activated Macrophages to Spreading Listeria monocytogenes
- (2012) Caroline Cole et al. IMMUNITY
- Dimethylarginine dimethylaminohydrolase 2, a newly identified mitochondrial protein modulating nitric oxide synthesis in normal human chondrocytes
- (2011) Berta Cillero-Pastor et al. ARTHRITIS AND RHEUMATISM
- MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response
- (2011) Fajian Hou et al. CELL
- Immune Signaling by RIG-I-like Receptors
- (2011) Yueh-Ming Loo et al. IMMUNITY
- Retinoic Acid-induced Gene-I (RIG-I) Associates with Nucleotide-binding Oligomerization Domain-2 (NOD2) to Negatively Regulate Inflammatory Signaling
- (2011) Stefanie A. Morosky et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Membrane Potential Is Required for MAVS-Mediated Antiviral Signaling
- (2011) T. Koshiba et al. Science Signaling
- Retinoic acid inducible gene-I, more than a virus sensor
- (2011) Feng Liu et al. Protein & Cell
- Mesenchymal stem cells improve murine acute coxsackievirus B3-induced myocarditis
- (2010) S. Van Linthout et al. EUROPEAN HEART JOURNAL
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1
- (2010) Kazuhide Onoguchi et al. PLoS Pathogens
- Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway
- (2009) Céline Castanier et al. EMBO REPORTS
- Negative Regulation of MAVS-Mediated Innate Immune Response by PSMA7
- (2009) Y. Jia et al. JOURNAL OF IMMUNOLOGY
- PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4
- (2009) Fuping You et al. NATURE IMMUNOLOGY
- RIG-I-like receptors: Sensing and responding to RNA virus infection
- (2009) Peyman Nakhaei et al. SEMINARS IN IMMUNOLOGY
- The IKK-related kinases: from innate immunity to oncogenesis
- (2008) Jean-François Clément et al. CELL RESEARCH
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- Nitric oxide inhibits human rhinovirus-induced transcriptional activation of CXCL10 in airway epithelial cells
- (2008) Rommy Koetzler et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A Chemical Inhibitor of DRP1 Uncouples Mitochondrial Fission and Apoptosis
- (2008) Atsushi Tanaka et al. MOLECULAR CELL
- Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?
- (2008) Tieu-Lan Chau et al. TRENDS IN BIOCHEMICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More