Structural basis for the prion-like MAVS filaments in antiviral innate immunity

Molecular Basis of NF-κB Signaling

(2013) Johanna Napetschnig et al.   Annual Review of Biophysics

ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon

(2013) Jenish R Patel et al.   EMBO REPORTS

Defining the functional determinants for RNA surveillance by RIG-I

(2013) Andrew Kohlway et al.   EMBO REPORTS

RIG-I Forms Signaling-Competent Filaments in an ATP-Dependent, Ubiquitin-Independent Manner

(2013) Alys Peisley et al.   MOLECULAR CELL

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

(2013) Sohini Mukherjee et al.   NATURE

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

(2013) Siqi Liu et al.   eLife

Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5

(2012) Bin Wu et al.   CELL

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

(2012) Ian C Berke et al.   EMBO JOURNAL

Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response

(2012) Xiaomo Jiang et al.   IMMUNITY

Unclosed HIV-1 Capsids Suggest a Curled Sheet Model of Assembly

(2012) Zhiheng Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

Duplex RNA activated ATPases (DRAs)

(2012) Dahai Luo et al.   RNA Biology

Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-I

(2012) Dahai Luo et al.   STRUCTURE

Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA

(2011) Eva Kowalinski et al.   CELL

Structural Insights into RNA Recognition by RIG-I

(2011) Dahai Luo et al.   CELL

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling

(2011) Filiz Civril et al.   EMBO REPORTS

RNA helicase retinoic acid-inducible gene I as a sensor of Hantaan virus replication

(2011) M.-H. Lee et al.   JOURNAL OF GENERAL VIROLOGY

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

(2011) Fuguo Jiang et al.   NATURE

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

(2011) A. Peisley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Membrane Potential Is Required for MAVS-Mediated Antiviral Signaling

(2011) T. Koshiba et al.   Science Signaling

The death-fold superfamily of homotypic interaction motifs

(2011) Kristof Kersse et al.   TRENDS IN BIOCHEMICAL SCIENCES

What the Myddosome structure tells us about the initiation of innate immunity

(2011) Nicholas J. Gay et al.   TRENDS IN IMMUNOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity

(2010) Wenwen Zeng et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

SF1 and SF2 helicases: family matters

(2010) Margaret E Fairman-Williams et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Short Double-stranded RNAs with an Overhanging 5′ ppp-Nucleotide, as Found in Arenavirus Genomes, Act as RIG-I Decoys

(2010) Jean-Baptiste Marq et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and Regulation

(2010) Chao Zheng et al.   MOLECULAR CELL

Two-layer membranes of calcium phosphate/collagen/PLGA nanofibres: in vitro biomineralisation and osteogenic differentiation of human mesenchymal stem cells

(2010) Nora Hild et al.   Nanoscale

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

(2010) Su-Chang Lin et al.   NATURE

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Plant and Animal Sensors of Conserved Microbial Signatures

(2010) P. C. Ronald et al.   SCIENCE

Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1

(2010) Kazuhide Onoguchi et al.   PLoS Pathogens

Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway

(2009) Céline Castanier et al.   EMBO REPORTS

A Nonself RNA Pattern: Tri-p to Panhandle

(2009) Takashi Fujita   IMMUNITY

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration

(2009) H. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitofusin 2 Inhibits Mitochondrial Antiviral Signaling

(2009) K. Yasukawa et al.   Science Signaling

Three-Dimensional Resolution Doubling in Wide-Field Fluorescence Microscopy by Structured Illumination

(2008) Mats G.L. Gustafsson et al.   BIOPHYSICAL JOURNAL

RNA recognition and signal transduction by RIG-I-like receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNOLOGICAL REVIEWS

Agonist and Antagonist Recognition by RIG-I, a Cytoplasmic Innate Immunity Receptor

(2008) C. T. Ranjith-Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Function of LGP2, a DEX(D/H) Helicase That Regulates the Innate Immunity Response

(2008) Ayaluru Murali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Enzyme Localization by Polymerization: Polymer Formation by the SAM Domain of Diacylglycerol Kinase δ1

(2008) Bryan T. Harada et al.   STRUCTURE

Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain

(2008) Jane A Potter et al.   BMC STRUCTURAL BIOLOGY