Milk Peptides as Novel Multi‐Targeted Therapeutic Candidates for SARS-CoV2

Anti-HCV, nucleotide inhibitors, repurposing against COVID-19

(2020) Abdo A. Elfiky   LIFE SCIENCES

Potential RNA-dependent RNA polymerase inhibitors as prospective therapeutics against SARS-CoV-2

(2020) Rudramani Pokhrel et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Cathepsin L-selective inhibitors: A potentially promising treatment for COVID-19 patients

(2020) Tianxiao Liu et al.   PHARMACOLOGY & THERAPEUTICS

De novo development of proteolytically resistant therapeutic peptides for oral administration

(2020) Xu-Dong Kong et al.   Nature Biomedical Engineering

SARS-CoV-2, More than a Respiratory Virus: Its Potential Role in Neuropathogenesis

(2020) Chitra Mohinder Singh Singal et al.   ACS Chemical Neuroscience

Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

(2020) Yuan Huang et al.   ACTA PHARMACOLOGICA SINICA

Advances in research on ACE2 as a receptor for 2019-nCoV

(2020) Jie Wu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

COVID-19: Drug Targets and Potential Treatments

(2020) Carmen Gil et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure of Furin Protease Binding to SARS-CoV-2 Spike Glycoprotein and Implications for Potential Targets and Virulence

(2020) Naveen Vankadari   Journal of Physical Chemistry Letters

Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach

(2020) Syed Ovais Aftab et al.   Journal of Translational Medicine

Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

(2020) Yuan-Lin Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

(2020) Athri D. Rathnayake et al.   Science Translational Medicine

Insights into Lysosomal PI(3,5)P2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex

(2020) Joshua A. Lees et al.   MOLECULAR CELL

ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19

(2020) Donato Zipeto et al.   Frontiers in Immunology

In Silico Structure-Based Repositioning of Approved Drugs for Spike Glycoprotein S2 Domain Fusion Peptide of SARS-CoV-2: Rationale from Molecular Dynamics and Binding Free Energy Calculations

(2020) Nishant Shekhar et al.   mSystems

Pharmacological hypothesis: TPC2 antagonist tetrandrine as a potential therapeutic agent for COVID‐19

(2020) Paula M. Heister et al.   Pharmacology Research & Perspectives

Investigation of beta-lactoglobulin derived bioactive peptides against SARS-CoV-2 (COVID-19): In silico analysis

(2020) Bilal Çakır et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Repurposing of some anti‐infective drugs for COVID‐19 treatment: A surveillance study supported by an in silico investigation

(2020) Ahmed M. Sayed et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Structural mechanisms of phospholipid activation of the human TPC2 channel

(2019) Ji She et al.   eLife

Discovery, synthesis, and in vitro evaluation of a novel bioactive peptide for ACE and DPP-IV inhibitory activity

(2019) Arpitha Ashok et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antioxidative Role of Buffalo (Bubalus bubalis) Colostrum Whey Derived Peptides During Oxidative Damage

(2018) N. R. Ashok et al.   International Journal of Peptide Research and Therapeutics

Empirical and bioinformatic characterization of buffalo ( Bubalus bubalis ) colostrum whey peptides & their angiotensin I-converting enzyme inhibition

(2017) N.R. Ashok et al.   FOOD CHEMISTRY

Comprehensive characterization of bioactive peptides from Buffalo ( Bubalus bubalis ) colostrum and milk fat globule membrane proteins

(2017) N. Brijesha et al.   FOOD RESEARCH INTERNATIONAL

Docking of Macrocycles: Comparing Rigid and Flexible Docking in Glide

(2017) Hiba Alogheli et al.   Journal of Chemical Information and Modeling

Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic

(2017) Kangmin He et al.   NATURE

Inhibitory potential of Buffalo (Bubalus bubalis) colostrum immunoglobulin G on Klebsiella pneumoniae

(2016) Mamatha Bhanu L.S. et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Diverse array-designed modes of combination therapies in Fangjiomics

(2015) Jun Liu et al.   ACTA PHARMACOLOGICA SINICA

Improved Peptide and Protein Torsional Energetics with the OPLS-AA Force Field

(2015) Michael J. Robertson et al.   Journal of Chemical Theory and Computation

OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins

(2015) Edward Harder et al.   Journal of Chemical Theory and Computation

AP-2-Associated Protein Kinase 1 and Cyclin G-Associated Kinase Regulate Hepatitis C Virus Entry and Are Potential Drug Targets

(2015) Gregory Neveu et al.   JOURNAL OF VIROLOGY

What we know but do not understand about nidovirus helicases

(2015) Kathleen C. Lehmann et al.   VIRUS RESEARCH

Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies

(2014) Apirat Chaikuad et al.   BIOCHEMICAL JOURNAL

Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

(2014) Jean Kaoru Millet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium

(2013) S. Bertram et al.   JOURNAL OF VIROLOGY

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

(2013) Anna M. Mielech et al.   VIROLOGY

A variant peptide of buffalo colostrum β-lactoglobulin inhibits angiotensin I-converting enzyme activity

(2012) A.C. Rohit et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cleavage and Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by Human Airway Trypsin-Like Protease

(2011) S. Bertram et al.   JOURNAL OF VIROLOGY

Angiotensin-Converting Enzyme 2: The First Decade

(2011) Nicola E. Clarke et al.   International Journal of Hypertension

Identifying and Characterizing Binding Sites and Assessing Druggability

(2009) Thomas A. Halgren   Journal of Chemical Information and Modeling

The SARS-CoV nucleocapsid protein: A protein with multifarious activities

(2007) Milan Surjit et al.   INFECTION GENETICS AND EVOLUTION