Antibacterial fatty acids: An update of possible mechanisms of action and implications in the development of the next-generation of antibacterial agents

Antibacterial Activity of Hexadecynoic Acid Isomers toward Clinical Isolates of Multidrug‐Resistant Staphylococcus aureus

(2020) David J. Sanabria‐Ríos et al.   LIPIDS

Fatty Acids as Antibiofilm and Antivirulence Agents

(2020) Prasun Kumar et al.   TRENDS IN MICROBIOLOGY

Accelerated evolution of bacterial antibiotic resistance through early emerged stress responses driven by photocatalytic oxidation

(2020) Hongliang Yin et al.   APPLIED CATALYSIS B-ENVIRONMENTAL

Disruption of quorum sensing and virulence in Burkholderia cenocepacia by a structural analogue of the cis-2-dodecenoic acid signal

(2019) Chaoyu Cui et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antibacterial Free Fatty Acids and Monoglycerides: Biological Activities, Experimental Testing, and Therapeutic Applications

(2018) Bo Yoon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Unsaturated Fatty Acids Affect Quorum Sensing Communication System and Inhibit Motility and Biofilm Formation of Acinetobacter baumannii

(2018) Marion Nicol et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-oral common pathogenic bacterial active acetylenic acids from Thesium chinense Turcz

(2018) Chang Liu et al.   Journal of Natural Medicines

Lauric Acid Is an Inhibitor of Clostridium difficile Growth in Vitro and Reduces Inflammation in a Mouse Infection Model

(2018) Hsiao-Ting Yang et al.   Frontiers in Microbiology

Interference in Bacterial Quorum Sensing: A Biopharmaceutical Perspective

(2018) Benjamin Rémy et al.   Frontiers in Pharmacology

Conjugation inhibitors compete with palmitic acid for binding to the conjugative traffic ATPase TrwD, providing a mechanism to inhibit bacterial conjugation

(2018) Yolanda García-Cazorla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclopropane-Containing Fatty Acids from the Marine Bacterium Labrenzia sp. 011 with Antimicrobial and GPR84 Activity

(2018) Jamshid Amiri Moghaddam et al.   Marine Drugs

7,10-Epoxyoctadeca-7,9-dienoic Acid: A Small Molecule Adjuvant That Potentiates β-Lactam Antibiotics Against Multidrug-Resistant Staphylococcus aureus

(2017) Chakradhar Dasagrandhi et al.   INDIAN JOURNAL OF MICROBIOLOGY

Docosahexaenoic acid loaded lipid nanoparticles with bactericidal activity against Helicobacter pylori

(2017) Catarina Leal Seabra et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

2-Methoxylated FA Display Unusual Antibacterial Activity Towards Clinical Isolates of Methicillin-Resistant Staphylococcus aureus (CIMRSA) and Escherichia coli

(2017) Néstor M. Carballeira et al.   LIPIDS

Antibacterial Effect of Eicosapentaenoic Acid against Bacillus cereus and Staphylococcus aureus: Killing Kinetics, Selection for Resistance, and Potential Cellular Target

(2017) Phuc Le et al.   Marine Drugs

Antibacterial activities of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) against planktonic and biofilm growing Streptococcus mutans

(2017) Mengjun Sun et al.   MICROBIAL PATHOGENESIS

Prevention of Ophthalmia Neonatorum Caused by Neisseria gonorrhoeae Using a Fatty Acid-Based Formulation

(2017) Colin P. Churchward et al.   mBio

Enhancement of antimicrobial activity by liposomal oleic acid-loaded antibiotics for the treatment of multidrug-resistant Pseudomonas aeruginosa

(2017) Pradeep Pushparaj Selvadoss et al.   Artificial Cells Nanomedicine and Biotechnology

Molecular mechanisms of membrane targeting antibiotics

(2016) Richard M. Epand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Highly enhanced bactericidal effects of medium chain fatty acids (caprylic, capric, and lauric acid) combined with edible plant essential oils (carvacrol, eugenol, β-resorcylic acid, trans -cinnamaldehyde, thymol, and vanillin) against Escherichia coli O157:H7

(2016) S.A. Kim et al.   FOOD CONTROL

Antimicrobial activity of a novel furan fatty acid, 7,10-epoxyoctadeca-7,9-dienoic acid against methicillin-resistant Staphylococcus aureus

(2016) Chakradhar Dasagrandhi et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Evaluation of the tannic acid inhibitory effect against the NorA efflux pump of Staphylococcus aureus

(2016) Saulo R. Tintino et al.   MICROBIAL PATHOGENESIS

Antibacterial and antibiofilm activities of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) against periodontopathic bacteria

(2016) Mengjun Sun et al.   MICROBIAL PATHOGENESIS

Type IV traffic ATPase TrwD as molecular target to inhibit bacterial conjugation

(2016) Jorge Ripoll-Rozada et al.   MOLECULAR MICROBIOLOGY

Bacterial Protein Synthesis as a Target for Antibiotic Inhibition

(2016) Stefan Arenz et al.   Cold Spring Harbor Perspectives in Medicine

Fatty acid microemulsion for the treatment of neonatal conjunctivitis: quantification, characterisation and evaluation of antimicrobial activity

(2016) Ummara Butt et al.   Drug Delivery and Translational Research

Conjugated Linoleic Acid Reduces Cholera Toxin ProductionIn VitroandIn Vivoby Inhibiting Vibrio cholerae ToxT Activity

(2015) Jeffrey H. Withey et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chemical conjugation of 2-hexadecynoic acid to C5-curcumin enhances its antibacterial activity against multi-drug resistant bacteria

(2015) David J. Sanabria-Ríos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Heterotrophic microalgae cultivation to synergize biodiesel production with waste remediation: Progress and perspectives

(2015) S. Venkata Mohan et al.   BIORESOURCE TECHNOLOGY

Mechanism for Inhibition of Vibrio cholerae ToxT Activity by the Unsaturated Fatty Acid Components of Bile

(2015) Sarah C. Plecha et al.   JOURNAL OF BACTERIOLOGY

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

(2015) Tihomir Tomašič et al.   JOURNAL OF MEDICINAL CHEMISTRY

Spectrum of Membrane Morphological Responses to Antibacterial Fatty Acids and Related Surfactants

(2015) Bo Kyeong Yoon et al.   LANGMUIR

Synthetic Fatty Acids Prevent Plasmid-Mediated Horizontal Gene Transfer

(2015) María Getino et al.   mBio

Mechanism of Antibacterial Activity of Liposomal Linolenic Acid against Helicobacter pylori

(2015) Sung Woo Jung et al.   PLoS One

Bactericidal Activity of the Human Skin Fatty Acidcis-6-Hexadecanoic Acid on Staphylococcus aureus

(2014) Michaël L. Cartron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanism and structure of the bacterial type IV secretion systems

(2014) Peter J. Christie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Targeting Bacterial Central Metabolism for Drug Development

(2014) Paul Murima et al.   CHEMISTRY & BIOLOGY

Antibacterial activity of 2-alkynoic fatty acids against multidrug-resistant bacteria

(2013) David J. Sanabria-Ríos et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Anti-bacterial and anti-inflammatory properties of capric acid against Propionibacterium acnes: A comparative study with lauric acid

(2013) Wen-Cheng Huang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Membrane Disruption by Antimicrobial Fatty Acids Releases Low-Molecular-Weight Proteins from Staphylococcus aureus

(2012) J. B. Parsons et al.   JOURNAL OF BACTERIOLOGY

Quorum Sensing Inhibitors Increase the Susceptibility of Bacterial Biofilms to Antibiotics In Vitro and In Vivo

(2011) Gilles Brackman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ecology and Evolution as Targets: the Need for Novel Eco-Evo Drugs and Strategies To Fight Antibiotic Resistance

(2011) Fernando Baquero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lyngbyoic acid, a “tagged” fatty acid from a marine cyanobacterium, disrupts quorum sensing in Pseudomonas aeruginosa

(2011) Jason Christopher Kwan et al.   Molecular BioSystems

Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors

(2011) J. B. Parsons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty acid extracts from Lucilia sericata larvae promote murine cutaneous wound healing by angiogenic activity

(2010) Zhen Zhang et al.   Lipids in Health and Disease

Bacterial Quorum-Sensing Network Architectures

(2009) Wai-Leung Ng et al.   Annual Review of Genetics

Antibacterial free fatty acids: activities, mechanisms of action and biotechnological potential

(2009) Andrew P. Desbois et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Antimicrobial Property of Lauric Acid Against Propionibacterium Acnes: Its Therapeutic Potential for Inflammatory Acne Vulgaris

(2009) Teruaki Nakatsuji et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Staphylococcus aureus Response to Unsaturated Long Chain Free Fatty Acids: Survival Mechanisms and Virulence Implications

(2009) John G. Kenny et al.   PLoS One