Advances in immunotherapeutic targets for childhood cancers: a focus on glypican-2 and B7-H3

Preclinical assessment of the efficacy and specificity of GD2-B7H3 SynNotch CAR-T in metastatic neuroblastoma

(2021) Babak Moghimi et al.   Nature Communications

The B7-H3-targeting antibody-drug conjugate m276-SL-PBD is potently effective against pediatric cancer preclinical solid tumor models

(2021) Nathan M. Kendsersky et al.   CLINICAL CANCER RESEARCH

Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032

(2021) Alice L. Yu et al.   CLINICAL CANCER RESEARCH

Combination of CD19 and CD22 CAR‐T cell therapy in relapsed B‐cell acute lymphoblastic leukemia after allogeneic transplantation

(2021) Shuangyou Liu et al.   AMERICAN JOURNAL OF HEMATOLOGY

Wilms’ tumor gene 1 is an independent prognostic factor for pediatric acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation

(2021) Dao-Xing Deng et al.   BMC CANCER

MiR-29c downregulates tumor-expressed B7-H3 to mediate the antitumor NK-cell functions in ovarian cancer

(2021) Mengqi Deng et al.   GYNECOLOGIC ONCOLOGY

Long-Term Follow-Up of CD19-CAR T-Cell Therapy in Children and Young Adults With B-ALL

(2021) Nirali N. Shah et al.   JOURNAL OF CLINICAL ONCOLOGY

Durable Remission Following “Off-the-Shelf” Chimeric Antigen Receptor (CAR) T-Cells in Patients with Relapse/Refractory (R/R) B-Cell Malignancies

(2020) Kevin J. Curran et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Correlation of CD123 Expression Level with Disease Characteristics and Outcomes in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

(2020) Adam J. Lamble et al.   BLOOD

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma

(2020) Jennifer N. Brudno et al.   NATURE MEDICINE

B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression

(2020) Ruoqin Wang et al.   Cell Death & Disease

Investigation of the Role of Dinutuximab Beta-Based Immunotherapy in the SIOPEN High-Risk Neuroblastoma 1 Trial (HR-NBL1)

(2020) Ladenstein et al.   Cancers

CD4/CD8 T-Cell Selection Affects Chimeric Antigen Receptor (CAR) T-Cell Potency and Toxicity: Updated Results From a Phase I Anti-CD22 CAR T-Cell Trial

(2020) Nirali N. Shah et al.   JOURNAL OF CLINICAL ONCOLOGY

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1–2 trial

(2020) Kara L Davis et al.   LANCET ONCOLOGY

Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors

(2020) Johanna Theruvath et al.   NATURE MEDICINE

Efficacy of B7-H3-Redirected BiTE and CAR-T Immunotherapies Against Extranodal Nasal Natural Killer/T Cell Lymphoma

(2020) Meijun Zheng et al.   Translational Oncology

B7-H3 Regulates Glioma Growth and Cell Invasion Through a JAK2/STAT3/Slug-Dependent Signaling Pathway

(2020) Chuanhong Zhong et al.   OncoTargets and Therapy

Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy

(2020) Solin Ali et al.   Frontiers in Immunology

Flow cytometric evaluation of CD38 expression levels in the newly diagnosed T-cell acute lymphoblastic leukemia and the effect of chemotherapy on its expression in measurable residual disease, refractory disease and relapsed disease: an implication for anti-CD38 immunotherapy

(2020) Prashant Ramesh Tembhare et al.   Journal for ImmunoTherapy of Cancer

Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma

(2020) Carlos A. Ramos et al.   JOURNAL OF CLINICAL ONCOLOGY

Rituximab for High-Risk, Mature B-Cell Non-Hodgkin’s Lymphoma in Children

(2020) Véronique Minard-Colin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma

(2020) Meenakshi Hegde et al.   Nature Communications

B7-H3-Targeted CAR-T Cells Exhibit Potent Antitumor Effects on Hematologic and Solid Tumors

(2020) Zongliang Zhang et al.   Molecular Therapy-Oncolytics

Inducible secretion of IL-21 augments anti-tumor activity of piggyBac-manufactured chimeric antigen receptor T cells

(2020) Martin Štach et al.   CYTOTHERAPY

Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis

(2020) Andras Heczey et al.   NATURE MEDICINE

Overexpression of CD200 and CD123 is a major influential factor in the clinical course of pediatric acute myeloid leukemia

(2020) Eman Z. Kandeel et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

CAR T cells targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors

(2019) Robbie G. Majzner et al.   CLINICAL CANCER RESEARCH

Targeted radioimmunotherapy for embryonal tumor with multilayered rosettes

(2019) Kayleen Bailey et al.   JOURNAL OF NEURO-ONCOLOGY

Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells

(2019) Hongwei Du et al.   CANCER CELL

8CD19 Chimeric Antigen Receptor (CAR) Engineered Epstein-Barr Virus (EBV) Specific T cells – An Off-the-Shelf, Allogeneic CAR T-Cell Immunotherapy Platform

(2019) R.R. Shen et al.   CYTOTHERAPY

A Frizzled‐Like Cysteine‐Rich Domain in Glypican‐3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice

(2019) Na Li et al.   HEPATOLOGY

Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope

(2019) Laura Orellana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequent B7-H3 overexpression in craniopharyngioma

(2019) Caili Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The novel non-immunological role and underlying mechanisms of B7-H3 in tumorigenesis

(2019) Xiangqi Zhou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

B7-H3 as a novel CAR-T therapeutic target for glioblastoma

(2019) Xin Tang et al.   Molecular Therapy-Oncolytics

NKT cells co-expressing a GD2-specific chimeric antigen receptor and IL-15 show enhanced in vivo persistence and antitumor activity against neuroblastoma

(2019) Xin Xu et al.   CLINICAL CANCER RESEARCH

B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres

(2019) Dean Nehama et al.   EBioMedicine

The Role of Glypican-3 in Regulating Wnt, YAP, and Hedgehog in Liver Cancer

(2019) Aarti Kolluri et al.   Frontiers in Oncology

B7-H3 specific T cells with chimeric antigen receptor and decoy PD-1 receptors eradicate established solid human tumors in mouse models

(2019) Baozhu Huang et al.   OncoImmunology

Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1–2 trial

(2019) Birgit Geoerger et al.   LANCET ONCOLOGY

B7–H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors

(2019) Uday B. Maachani et al.   Translational Oncology

Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia

(2018) Karen L. Bride et al.   BLOOD

Adoptive immunotherapy using PRAME-specific T cells in medulloblastoma

(2018) Domenico Orlando et al.   CANCER RESEARCH

First pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: report of three cases

(2018) Weili Sun et al.   Journal of Hematology & Oncology

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

(2018) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma

(2018) Noah E. Berlow et al.   PLoS One

R-spondins can potentiate WNT signaling without LGRs

(2018) Andres M Lebensohn et al.   eLife

Durable regression of Medulloblastoma after regional and intravenous delivery of anti-HER2 chimeric antigen receptor T cells

(2018) Anandani Nellan et al.   Journal for ImmunoTherapy of Cancer

Tumor B7-H3 (CD276) Expression and Survival in Pancreatic Cancer

(2018) Kentaro Inamura et al.   Journal of Clinical Medicine

Clinical significance of serum soluble B7-H3 in patients with osteosarcoma

(2018) Ling Wang et al.   Cancer Cell International

Brentuximab vedotin with gemcitabine for paediatric and young adult patients with relapsed or refractory Hodgkin's lymphoma (AHOD1221): a Children's Oncology Group, multicentre single-arm, phase 1–2 trial

(2018) Peter D Cole et al.   LANCET ONCOLOGY

B7-H3 promotes metastasis, proliferation, and epithelial-mesenchymal transition in lung adenocarcinoma

(2018) Ting-Ting Yu et al.   OncoTargets and Therapy

Preclinical Development of Bivalent Chimeric Antigen Receptors Targeting Both CD19 and CD22

(2018) Haiying Qin et al.   Molecular Therapy-Oncolytics

Phase II study of ipilimumab in adolescents with unresectable stage III or IV malignant melanoma

(2017) Birgit Geoerger et al.   EUROPEAN JOURNAL OF CANCER

A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence

(2017) Nan Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Early Detection of Hepatocellular Carcinoma in Patients with Hepatocirrhosis by Soluble B7-H3

(2017) Long Zhao et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study

(2017) Michael J Overman et al.   LANCET ONCOLOGY

Gemtuzumab ozogamicin in acute myeloid leukemia

(2017) C D Godwin et al.   LEUKEMIA

PRAME overexpression predicted good outcome in pediatric B-cell acute lymphoblastic leukemia patients receiving chemotherapy

(2017) Yan-Huan Zhang et al.   LEUKEMIA RESEARCH

Function of Novel Anti-CD19 Chimeric Antigen Receptors with Human Variable Regions Is Affected by Hinge and Transmembrane Domains

(2017) Leah Alabanza et al.   MOLECULAR THERAPY

Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase

(2017) Alec J. Walker et al.   MOLECULAR THERAPY

CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy

(2017) Terry J Fry et al.   NATURE MEDICINE

B7-H3 is related to tumor progression in ovarian cancer

(2017) Jingjing Zhang et al.   ONCOLOGY REPORTS

Patterns of PD-1, PD-L1, and PD-L2 expression in pediatric solid tumors

(2017) Navin Pinto et al.   PEDIATRIC BLOOD & CANCER

Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma

(2017) Nan Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B7-H3 Promotes the Migration and Invasion of Human Bladder Cancer Cells via the PI3K/Akt/STAT3 Signaling Pathway

(2017) Yuchao Li et al.   Journal of Cancer

A tandem CD19/CD20 CAR lentiviral vector drives on-target and off-target antigen modulation in leukemia cell lines

(2017) Dina Schneider et al.   Journal for ImmunoTherapy of Cancer

Five-year survival and durability results of brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma

(2016) R. Chen et al.   BLOOD

Preclinical Assessment of CD171-Directed CAR T-cell Adoptive Therapy for Childhood Neuroblastoma: CE7 Epitope Target Safety and Product Manufacturing Feasibility

(2016) Annette Künkele et al.   CLINICAL CANCER RESEARCH

Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy

(2016) E. Picarda et al.   CLINICAL CANCER RESEARCH

Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia

(2016) Arend von Stackelberg et al.   JOURNAL OF CLINICAL ONCOLOGY

Antigen-specific immunoreactivity and clinical outcome following vaccination with glioma-associated antigen peptides in children with recurrent high-grade gliomas: results of a pilot study

(2016) Ian F. Pollack et al.   JOURNAL OF NEURO-ONCOLOGY

Inotuzumab Ozogamicin versus Standard Therapy for Acute Lymphoblastic Leukemia

(2016) Hagop M. Kantarjian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain in heparan sulfate

(2016) Wei Gao et al.   Scientific Reports

Soluble B7-H3 promotes the invasion and metastasis of pancreatic carcinoma cells through the TLR4/NF-κB pathway

(2016) Chao Xie et al.   Scientific Reports

Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma

(2015) N. W. C. J. van de Donk et al.   BLOOD

A phase I trial combining decitabine/dendritic cell vaccine targeting MAGE-A1, MAGE-A3 and NY-ESO-1 for children with relapsed or therapy-refractory neuroblastoma and sarcoma

(2015) Deepa K. Krishnadas et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Phase I Clinical Trial of Ipilimumab in Pediatric Patients with Advanced Solid Tumors

(2015) M. S. Merchant et al.   CLINICAL CANCER RESEARCH

Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3

(2015) Mahiuddin Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia

(2015) S S Kenderian et al.   LEUKEMIA

Targeting Wnts at the Source--New Mechanisms, New Biomarkers, New Drugs

(2015) B. Madan et al.   MOLECULAR CANCER THERAPEUTICS

Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma

(2015) Henk M. Lokhorst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pediatric solid tumor genomics and developmental pliancy

(2015) X Chen et al.   ONCOGENE

Overexpression of B7-H3 augments anti-apoptosis of colorectal cancer cells by Jak2-STAT3

(2015) Ting Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis

(2015) Wei Gao et al.   Nature Communications

Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma

(2015) Lotte Spel et al.   Oncotarget

Ablation of B7-H3 but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

(2015) K. Kreymborg et al.   Cancer Immunology Research

B7-H3 protein expression in acute myeloid leukemia

(2015) Thomas Guery et al.   Cancer Medicine

EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma

(2015) et al.   JOURNAL OF HEPATOLOGY

Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients

(2014) A. E. Frankel et al.   BLOOD

Childhood and adolescent cancer statistics, 2014

(2014) Elizabeth Ward et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Anti-CD33 chimeric antigen receptor targeting of acute myeloid leukemia

(2014) C. O'Hear et al.   HAEMATOLOGICA

Glypican-3 binds to Frizzled and plays a direct role in the stimulation of canonical Wnt signaling

(2014) M. Capurro et al.   JOURNAL OF CELL SCIENCE

Antigen-Specific Immune Responses and Clinical Outcome After Vaccination With Glioma-Associated Antigen Peptides and Polyinosinic-Polycytidylic Acid Stabilized by Lysine and Carboxymethylcellulose in Children With Newly Diagnosed Malignant Brainstem and Nonbrainstem Gliomas

(2014) Ian F. Pollack et al.   JOURNAL OF CLINICAL ONCOLOGY

Gemtuzumab Ozogamicin in Children and Adolescents With De Novo Acute Myeloid Leukemia Improves Event-Free Survival by Reducing Relapse Risk: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531

(2014) Alan S. Gamis et al.   JOURNAL OF CLINICAL ONCOLOGY

Diverse Solid Tumors Expressing a Restricted Epitope of L1-CAM Can Be Targeted by Chimeric Antigen Receptor Redirected T Lymphocytes

(2014) Hao Hong et al.   JOURNAL OF IMMUNOTHERAPY

Her3 is associated with poor survival of gastric adenocarcinoma: Her3 promotes proliferation, survival and migration of human gastric cancer mediated by PI3K/AKT signaling pathway

(2014) Xiaoyu Wu et al.   MEDICAL ONCOLOGY

EBP50 inhibits the migration and invasion of human breast cancer cells via LIMK/cofilin and the PI3K/Akt/mTOR/MMP signaling pathway

(2014) Hongli Li et al.   MEDICAL ONCOLOGY

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations

(2014) Faviel F. González-Galarza et al.   NUCLEIC ACIDS RESEARCH

In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

(2014) C. Wang et al.   Cancer Immunology Research

Targeting CD22 in B-cell Malignancies: Current Status and Clinical Outlook

(2013) Loretta Sullivan-Chang et al.   BIODRUGS

Cellular determinants for preclinical activity of a novel CD33/CD3 bispecific T-cell engager (BiTE) antibody, AMG 330, against human AML

(2013) G. S. Laszlo et al.   BLOOD

Blastic plasmacytoid dendritic cell neoplasm: clinical features in 90 patients

(2013) F. Julia et al.   BRITISH JOURNAL OF DERMATOLOGY

Redirection of T cells with a first fully humanized bispecific CD33–CD3 antibody efficiently eliminates AML blasts without harming hematopoietic stem cells

(2013) C Arndt et al.   LEUKEMIA

Ch14.18 antibody produced in CHO cells in relapsed or refractory Stage 4 neuroblastoma patients

(2013) Ruth Ladenstein et al.   mAbs

Immunohistochemical Expression of Glypican-3 in Pediatric Tumors: An Analysis of 414 Cases

(2013) Elaine S. Chan et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

BIRC5(survivin) splice variant expression correlates with refractory disease and poor outcome in pediatric acute myeloid leukemia: A report from the Children's Oncology Group

(2013) Andrew S. Moore et al.   PEDIATRIC BLOOD & CANCER

Proteome Profiling of Neuroblastoma-Derived Exosomes Reveal the Expression of Proteins Potentially Involved in Tumor Progression

(2013) Danilo Marimpietri et al.   PLoS One

Identification and Characterization of Angiogenesis Targets through Proteomic Profiling of Endothelial Cells in Human Cancer Tissues

(2013) Mehdi Mesri et al.   PLoS One

Structure and T Cell Inhibition Properties of B7 Family Member, B7-H3

(2013) Vladimir Vigdorovich et al.   STRUCTURE

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

(2012) Marcel Kool et al.   ACTA NEUROPATHOLOGICA

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Development of an Fc-Enhanced Anti-B7-H3 Monoclonal Antibody with Potent Antitumor Activity

(2012) D. Loo et al.   CLINICAL CANCER RESEARCH

Crystal Structure ofN-Glycosylated Human Glypican-1 Core Protein

(2012) Gabriel Svensson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase II Trial of Trastuzumab in Combination With Cytotoxic Chemotherapy for Treatment of Metastatic Osteosarcoma With Human Epidermal Growth Factor Receptor 2 Overexpression: A Report From the Children's Oncology Group

(2012) David Ebb et al.   JOURNAL OF CLINICAL ONCOLOGY

Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas

(2012) Gordon Li et al.   JOURNAL OF NEURO-ONCOLOGY

NY-ESO-1 expression in synovial sarcoma and other mesenchymal tumors: significance for NY-ESO-1-based targeted therapy and differential diagnosis

(2012) Jin-Ping Lai et al.   MODERN PATHOLOGY

Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo

(2012) Nai-Kong V. Cheung et al.   OncoImmunology

Identification of Cell Surface Proteins as Potential Immunotherapy Targets in 12 Pediatric Cancers

(2012) Rimas J. Orentas et al.   Frontiers in Oncology

A Phase I Study of Gemtuzumab Ozogamicin (GO) in Combination with Busulfan and Cyclophosphamide (Bu/Cy) and Allogeneic Stem Cell Transplantation in Children with Poor-Risk CD33+ AML: A New Targeted Immunochemotherapy Myeloablative Conditioning (MAC) Regimen

(2011) Prakash Satwani et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma

(2011) C. U. Louis et al.   BLOOD

B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes

(2011) Christina Tekle et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of Wilms tumor 1 gene in a variety of pediatric tumors

(2011) Takaharu Oue et al.   JOURNAL OF PEDIATRIC SURGERY

WT1 peptide vaccination following allogeneic stem cell transplantation in pediatric leukemic patients with high risk for relapse: successful maintenance of durable remission

(2011) Y Hashii et al.   LEUKEMIA

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

(2011) Antonio Di Stasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

NF-κB promotes epithelial–mesenchymal transition, migration and invasion of pancreatic carcinoma cells

(2010) Harald J. Maier et al.   CANCER LETTERS

Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

(2010) S. De Brouwer et al.   CLINICAL CANCER RESEARCH

Glypican-3: A new target for cancer immunotherapy

(2010) Mitchell Ho et al.   EUROPEAN JOURNAL OF CANCER

B7-H3 Augments the Inflammatory Response and Is Associated with Human Sepsis

(2010) G. Zhang et al.   JOURNAL OF IMMUNOLOGY

Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas

(2010) Xingxing Zang et al.   MODERN PATHOLOGY

Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

(2010) Richard A Morgan et al.   MOLECULAR THERAPY

Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma

(2010) Alice L. Yu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

RANKL expression is related to treatment outcome of patients with localized, high-grade osteosarcoma

(2010) Jun Ah Lee et al.   PEDIATRIC BLOOD & CANCER

Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity

(2010) N. Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS

(2009) U. Keilholz et al.   BLOOD

A Phase II study of SGN-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma

(2009) Andres Forero-Torres et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

(2009) M. A. Cheever et al.   CLINICAL CANCER RESEARCH

EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

(2009) D. A. Bax et al.   CLINICAL CANCER RESEARCH

B7-H3 is a potent inhibitor of human T-cell activation: No evidence for B7-H3 and TREML2 interaction

(2009) Judith Leitner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Randomized Phase II Trial of Denosumab in Patients With Bone Metastases From Prostate Cancer, Breast Cancer, or Other Neoplasms After Intravenous Bisphosphonates

(2009) Karim Fizazi et al.   JOURNAL OF CLINICAL ONCOLOGY

A Phase 1 Study of Combotox in Pediatric Patients With Refractory B-lineage Acute Lymphoblastic Leukemia

(2009) Larry Herrera et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Diagnosis value of serum B7-H3 expression in non-small cell lung cancer

(2009) Guangbo Zhang et al.   LUNG CANCER

HER2/neu Expression: A Predictor for Differentiation and Survival in Children With Wilms Tumor

(2009) Seham M. Ragab et al.   PATHOLOGY & ONCOLOGY RESEARCH

CD33 Detection by Immunohistochemistry in Paraffin-Embedded Tissues

(2008) James D. Hoyer et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Oncofetal Protein Glypican-3 Distinguishes Yolk Sac Tumor From Clear Cell Carcinoma of the Ovary

(2008) Ghada E. Esheba et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy

(2008) M. N. Dworzak et al.   BLOOD

Soluble CD276 (B7-H3) is released from monocytes, dendritic cells and activated T cells and is detectable in normal human serum

(2008) Guangbo Zhang et al.   IMMUNOLOGY

Chemoimmunotherapy Reinduction With Epratuzumab in Children With Acute Lymphoblastic Leukemia in Marrow Relapse: A Children's Oncology Group Pilot Study

(2008) Elizabeth A. Raetz et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of ALK as a major familial neuroblastoma predisposition gene

(2008) Yaël P. Mossé et al.   NATURE

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

(2008) Martin A Pule et al.   NATURE MEDICINE

Correction for Hashiguchi et al., Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses

(2008)   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The contrasting role of B7-H3

(2008) K. A. Hofmeyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glypicans

(2008) Jorge Filmus et al.   GENOME BIOLOGY