Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-03-31
DOI
10.3389/fimmu.2020.00531
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory
- (2019) Mauro Poggio et al. CELL
- Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
- (2018) Alexander Drilon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Exosomes Associated with Human Ovarian Tumors Harbor a Reversible Checkpoint of T-cell Responses
- (2018) Gautam N. Shenoy et al. Cancer Immunology Research
- Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles
- (2018) Franz L. Ricklefs et al. Science Advances
- Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
- (2018) Gang Chen et al. NATURE
- Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications
- (2017) Hamid R. Mirzaei et al. Frontiers in Immunology
- Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms
- (2017) Laurent Muller et al. OncoImmunology
- Tumor-derived exosomes induce CD8+ T cell suppressors
- (2017) Brian T. Maybruck et al. Journal for ImmunoTherapy of Cancer
- Preclinical Assessment of CD171-Directed CAR T-cell Adoptive Therapy for Childhood Neuroblastoma: CE7 Epitope Target Safety and Product Manufacturing Feasibility
- (2016) Annette Künkele et al. CLINICAL CANCER RESEARCH
- The prognostic impact of soluble and vesicular HLA-G and its relationship to circulating tumor cells in neoadjuvant treated breast cancer patients
- (2016) Lisa König et al. HUMAN IMMUNOLOGY
- Exosomes and tumor-mediated immune suppression
- (2016) Theresa L. Whiteside JOURNAL OF CLINICAL INVESTIGATION
- Treatment of solid tumors with chimeric antigen receptor-engineered T cells: current status and future prospects
- (2016) Shengmeng Di et al. Science China-Life Sciences
- The Potential of HLA-G-Bearing Extracellular Vesicles as a Future Element in HLA-G Immune Biology
- (2016) Vera Rebmann et al. Frontiers in Immunology
- Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets
- (2016) Laurent Muller et al. Scientific Reports
- T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
- (2015) Daniel W Lee et al. LANCET
- Exosomes and their roles in immune regulation and cancer
- (2015) David W. Greening et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy
- (2015) Xiang-Jun Tang et al. Oncotarget
- Functional Tuning of CARs Reveals Signaling Threshold above Which CD8+ CTL Antitumor Potency Is Attenuated due to Cell Fas-FasL-Dependent AICD
- (2015) A. Kunkele et al. Cancer Immunology Research
- Formation and role of exosomes in cancer
- (2014) Lindsey T. Brinton et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
- (2014) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Expression of NTRK1/TrkA affects immunogenicity of neuroblastoma cells
- (2013) Kristian W. Pajtler et al. INTERNATIONAL JOURNAL OF CANCER
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Correction: Expression of the Neurotrophin Receptor TrkA Down-Regulates Expression and Function of Angiogenic Stimulators in SH-SY5Y Neuroblastoma Cells
- (2012) CANCER RESEARCH
- Neuroblastoma
- (2012) Andrew M. Davidoff Seminars in Pediatric Surgery
- Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
- (2011) R. J. Brentjens et al. BLOOD
- Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy
- (2011) Viktoriya Sokolova et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
- (2011) David L. Porter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc ‘spacer’ domain in the extracellular moiety of chimeric antigen receptors avoids ‘off-target’ activation and unintended initiation of an innate immune response
- (2010) A Hombach et al. GENE THERAPY
- Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cells
- (2008) J SCHULTE et al. DNA REPAIR
- Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
- (2008) Martin A Pule et al. NATURE MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started