B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

B7-H3 is regulated by BRD4 and promotes TLR4 expression in pancreatic ductal adenocarcinoma

(2019) Jingyuan Zhao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Immunotherapy in colorectal cancer: rationale, challenges and potential

(2019) Karuna Ganesh et al.   Nature Reviews Gastroenterology & Hepatology

Synergistic effect of immune checkpoint blockade and anti-angiogenesis in cancer treatment

(2019) Ming Yi et al.   Molecular Cancer

B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2

(2019) Tongguo Shi et al.   Cell Death & Disease

Combination of CTLA-4 and PD-1 blockers for treatment of cancer

(2019) Anand Rotte   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Gold as a Possible Alternative to Platinum-Based Chemotherapy for Colon Cancer Treatment

(2019) Inés Mármol et al.   Cancers

Role of MYC-miR-29-B7-H3 in Medulloblastoma Growth and Angiogenesis

(2019) Ian J. Purvis et al.   Journal of Clinical Medicine

CCR6 promotes tumor angiogenesis via the AKT/NF-κB/VEGF pathway in colorectal cancer

(2018) Cong-cong Zhu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice

(2018) Chongbiao Huang et al.   GASTROENTEROLOGY

Endothelial Tie1–mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis

(2018) Silvia La Porta et al.   JOURNAL OF CLINICAL INVESTIGATION

PARK2 inhibits osteosarcoma cell growth through the JAK2/STAT3/VEGF signaling pathway

(2018) Zhong Lei et al.   Cell Death & Disease

B7H3 As a Promoter of Metastasis and Promising Therapeutic Target

(2018) Peixin Dong et al.   Frontiers in Oncology

MicroRNA-506 inhibits the proliferation and invasion of mantle cell lymphoma cells by targeting B7 H3

(2018) Xiao-wen Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of SIRT2 limits tumour angiogenesis via inactivation of the STAT3/VEGFA signalling pathway

(2018) Fuqing Hu et al.   Cell Death & Disease

Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis

(2018) Zhicheng Zeng et al.   Nature Communications

Sulfated polysaccharide JCS1S2 inhibits angiogenesis via targeting VEGFR2/VEGF and blocking VEGFR2/Erk/VEGF signaling

(2018) Zheng Wang et al.   CARBOHYDRATE POLYMERS

Elevated Gab2 induces tumor growth and angiogenesis in colorectal cancer through upregulating VEGF levels

(2017) Chenbo Ding et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Non-canonical NOTCH3 signalling limits tumour angiogenesis

(2017) Shuheng Lin et al.   Nature Communications

Evaluation of the correlation of vasculogenic mimicry, ALDH1, KAI1 and microvessel density in the prediction of metastasis and prognosis in colorectal carcinoma

(2017) Bo Zhu et al.   BMC Surgery

B7-H3 Promotes the Migration and Invasion of Human Bladder Cancer Cells via the PI3K/Akt/STAT3 Signaling Pathway

(2017) Yuchao Li et al.   Journal of Cancer

DHX32 Promotes Angiogenesis in Colorectal Cancer Through Augmenting β-catenin Signaling to Induce Expression of VEGFA

(2017) Huayue Lin et al.   EBioMedicine

Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy

(2016) E. Picarda et al.   CLINICAL CANCER RESEARCH

Antiangiogenic therapy in oncology: current status and future directions

(2016) Gordon C Jayson et al.   LANCET

Ten years of anti-vascular endothelial growth factor therapy

(2016) Napoleone Ferrara et al.   NATURE REVIEWS DRUG DISCOVERY

Soluble B7-H3 promotes the invasion and metastasis of pancreatic carcinoma cells through the TLR4/NF-κB pathway

(2016) Chao Xie et al.   Scientific Reports

B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway

(2015) Fu-biao Kang et al.   Cancer Cell International

The Contribution of Angiogenesis to the Process of Metastasis

(2015) Diane R. Bielenberg et al.   CANCER JOURNAL

ILT4 drives B7-H3 expression via PI3K/AKT/mTOR signalling and ILT4/B7-H3 co-expression correlates with poor prognosis in non-small cell lung cancer

(2015) Pei Zhang et al.   FEBS LETTERS

Tumor angiogenesis, from foe to friend

(2015) L. B. Rivera et al.   SCIENCE

B7-H3 expression in breast cancer and upregulation of VEGF through gene silence

(2014) Jing Sun et al.   OncoTargets and Therapy

B7-H3 expression in colorectal cancer: Nuclear localization strongly predicts poor outcome in colon cancer

(2012) Vibeke Anett Ingebrigtsen et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor angiogenesis: molecular pathways and therapeutic targets

(2011) Sara M Weis et al.   NATURE MEDICINE

IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway

(2011) Azadeh Montaseri et al.   PLoS One

Clinical significance and regulation of the costimulatory molecule B7-H3 in human colorectal carcinoma

(2010) Jing Sun et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

NF-κB Signaling Pathway, Inflammation and Colorectal Cancer

(2010) Soly Wang et al.   Cellular & Molecular Immunology

NF-κB: a new player in angiostatic therapy

(2008) Sebastien P. Tabruyn et al.   ANGIOGENESIS

Bevacizumab in Combination With Oxaliplatin-Based Chemotherapy As First-Line Therapy in Metastatic Colorectal Cancer: A Randomized Phase III Study

(2008) Leonard B. Saltz et al.   JOURNAL OF CLINICAL ONCOLOGY

Regulation of metastasis in colorectal adenocarcinoma: A collision between development and tumor biology

(2008) J. Joshua Smith et al.   SURGERY