A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones

β-Functionalization of Indolin-2-one-Derived Aliphatic Acids for the Divergent Synthesis of Spirooxindole γ-Butyrolactones

(2017) Jing Cao et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective synthesis of spiro γ-butyrolactones by N-heterocyclic carbene (NHC)-catalyzed formal [3 + 2] annulation of enals with 3-hydroxy oxindoles

(2017) Subrata Mukherjee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate

(2017) Xiang-Yu Chen et al.   Chemical Science

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

(2016) Michael H. Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isatin Derived Spirocyclic Analogues with α-Methylene-γ-butyrolactone as Anticancer Agents: A Structure–Activity Relationship Study

(2016) Sandeep Rana et al.   JOURNAL OF MEDICINAL CHEMISTRY

1-Hydroxybenzotriazole-Assisted, N-Heterocyclic Carbene Catalyzed β-Functionalization of Saturated Carboxylic Esters: Access to Spirooxindole Lactones

(2016) Jianfeng Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Origin of Stereoselectivity in Cooperative Asymmetric Catalysis Involving N-Heterocyclic Carbenes and Lewis Acids toward the Synthesis of Spirooxindole Lactone

(2016) Yernaidu Reddi et al.   ACS Catalysis

Ferrocene-Based Planar Chiral Imidazopyridinium Salts for Catalysis

(2015) Christopher T. Check et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative catalysis of N-heterocyclic carbene and Brønsted acid for a highly enantioselective route to unprotected spiro-indoline-pyrans

(2015) Youqiang Lin et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

(2015) Rajeev S. Menon et al.   CHEMICAL SOCIETY REVIEWS

Nucleophilic β-Carbon Activation of Propionic Acid as a 3-Carbon Synthon by Carbene Organocatalysis

(2015) Zhichao Jin et al.   CHEMISTRY-A EUROPEAN JOURNAL

An NHC-Catalyzed In Situ Activation Strategy to β-Functionalize Saturated Carboxylic Acid: An Enantioselective Formal [3+2] Annulation for Spirocyclic Oxindolo-γ-butyrolactones

(2015) Yuanwei Xie et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic Carbene-Catalyzed Radical Reactions for Highly Enantioselective β-Hydroxylation of Enals

(2015) Yuexia Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Functionalization of Carboxylic Anhydrides with β-Alkyl Substituents through Carbene Organocatalysis

(2014) Zhichao Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Cyclocondensation of α,β-Unsaturated Carboxylic Acids: Enantioselective Synthesis of Pyrrolidinone and Dihydropyridinone Derivatives

(2014) Xiang-Yu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conjugate Umpolung of β,β-Disubstituted Enals by Dual Catalysis with an N-Heterocyclic Carbene and a Brønsted Acid: Facile Construction of Contiguous Quaternary Stereocenters

(2014) Jun-Long Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioconvergent Synthesis of Functionalized γ-Butyrolactones via (3 + 2)-Annulation

(2014) C. Guy Goodman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective N-Heterocyclic Carbene-Catalyzed β-Hydroxylation of Enals Using Nitroarenes: An Atom Transfer Reaction That Proceeds via Single Electron Transfer

(2014) Nicholas A. White et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Annulations for Dihydroquinolones by in Situ Generation of Azolium Enolates

(2014) Anna Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Homoenolate Additions to Acyl Phosphonates through Rational Design of a Tailored N-Heterocyclic Carbene Catalyst

(2013) Ki Po Jang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Carbon activation of saturated carboxylic esters through N-heterocyclic carbene organocatalysis

(2013) Zhenqian Fu et al.   Nature Chemistry

N-heterocyclic carbene catalyzed annulation of benzofuran-2,3-diones and enals: a concise synthesis of spiro-bis-lactone

(2013) Ze-Dong Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

(2012) Julien Dugal-Tessier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric induction afforded by chiral azolylidene N-heterocyclic carbenes (NHC) catalysts

(2012) Ragnhild B. Strand et al.   TETRAHEDRON-ASYMMETRY

Synergistic catalysis: A powerful synthetic strategy for new reaction development

(2012) Anna E. Allen et al.   Chemical Science

N-Heterocyclic carbene containing element organic frameworks as heterogeneous organocatalysts

(2011) Marcus Rose et al.   CHEMICAL COMMUNICATIONS

Highly diastereo- and enantioselective NHC-catalyzed [3+2] annulation of enals and isatins

(2011) Li-Hui Sun et al.   CHEMICAL COMMUNICATIONS

Umpolung of α,β-unsaturated aldehydes by electrogenerated NHCs in ionic liquids: Synthesis of γ-butyrolactones

(2011) Monica Orsini et al.   ELECTROCHEMISTRY COMMUNICATIONS

CooperativeN-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates

(2010) Benoit Cardinal-David et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereoselective Synthesis of Trifluoromethylated γ-Butyrolactonesvia N-Heterocyclic Carbene-Catalyzed Conjugated Umpolung of α,β-Unsaturated Aldehydes

(2008) Keiichi Hirano et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereoselective Synthesis of γ-ButyrolactonesviaOrganocatalytic Annulations of Enals and Keto Esters

(2008) Yi Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Cyclophane-Type Imidazolium Salts with Planar Chirality as a New Class of N-Heterocyclic Carbene Precursors

(2008) Yuki Matsuoka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalysis by bimacrocyclic NHCs: unexpected formation of a cyclic hemiacetal instead of a γ-butyrolactone

(2008) Ole Winkelmann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Autophagy-Modulating Aminosteroids Isolated from the SpongeCliona celata

(2008) Robert A. Keyzers et al.   ORGANIC LETTERS

Synthesis of anN-Mesityl Substituted Chiral Imidazolium Salt for NHC-Catalyzed Reactions

(2008) Justin R. Struble et al.   ORGANIC LETTERS

Chiral bicyclic imidazolium salts as a new class of N-heterocyclic carbene precursors

(2008) Yuki Matsuoka et al.   TETRAHEDRON LETTERS