Increased expression of tryptophan and tyrosine tRNAs elevates stop codon readthrough of reporter systems in human cell lines

Emerging Roles of tRNAs in RNA Virus Infections

(2020) Alexandre Nunes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Yeast applied readthrough inducing system (YARIS): an in vivo assay for the comprehensive study of translational readthrough

(2019) Petra Beznosková et al.   NUCLEIC ACIDS RESEARCH

tRNA Deregulation and Its Consequences in Cancer

(2019) Mafalda Santos et al.   TRENDS IN MOLECULAR MEDICINE

Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response

(2018) Gary Loughran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The dysregulation of tRNAs and tRNA derivatives in cancer

(2018) Shi-qiong Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Signaling Pathways Involved in the Regulation of mRNA Translation

(2018) Philippe P. Roux et al.   MOLECULAR AND CELLULAR BIOLOGY

Deciphering the reading of the genetic code by near-cognate tRNA

(2018) Sandra Blanchet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosome profiling of the retrovirus murine leukemia virus

(2018) Nerea Irigoyen et al.   Retrovirology

Translational readthrough generates new astrocyte AQP4 isoforms that modulate supramolecular clustering, glial endfeet localization, and water transport

(2017) Manuela De Bellis et al.   GLIA

The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis

(2017) Paul Schimmel   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Embraced by eIF3: structural and functional insights into the roles of eIF3 across the translation cycle

(2017) Leoš Shivaya Valášek et al.   NUCLEIC ACIDS RESEARCH

Avoidance of reporter assay distortions from fused dual reporters

(2017) Gary Loughran et al.   RNA

tRNA biology in the omics era: Stress signalling dynamics and cancer progression

(2016) Andrea Orioli   BIOESSAYS

Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression

(2016) Hani Goodarzi et al.   CELL

An Unprecedented Non-canonical Nuclear Genetic Code with All Three Termination Codons Reassigned as Sense Codons

(2016) Kristína Záhonová et al.   CURRENT BIOLOGY

Nonsense-mediated mRNA decay in humans at a glance

(2016) Tatsuaki Kurosaki et al.   JOURNAL OF CELL SCIENCE

Novel Ciliate Genetic Code Variants Including the Reassignment of All Three Stop Codons to Sense Codons inCondylostoma magnum

(2016) Stephen M. Heaphy et al.   MOLECULAR BIOLOGY AND EVOLUTION

Rules of UGA-N decoding by near-cognate tRNAs and analysis of readthrough on short uORFs in yeast

(2016) Petra Beznosková et al.   RNA

In-depth analysis ofcis-determinants that either promote or inhibit reinitiation onGCN4mRNA after translation of its four short uORFs

(2016) Stanislava Gunišová et al.   RNA

The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code

(2016) Julia Hofhuis et al.   Open Biology

Functional Translational Readthrough: A Systems Biology Perspective

(2016) Fabian Schueren et al.   PLoS Genetics

Translation initiation factor eIF3 promotes programmed stop codon readthrough

(2015) Petra Beznosková et al.   NUCLEIC ACIDS RESEARCH

GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes

(2015) Patricia P. Chan et al.   NUCLEIC ACIDS RESEARCH

Nonsense suppression by near-cognate tRNAs employs alternative base pairing at codon positions 1 and 3

(2015) Bijoyita Roy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translational readthrough potential of natural termination codons in eucaryotes – The impact of RNA sequence

(2015) Maciej Dabrowski et al.   RNA Biology

Therapeutics Based on Stop Codon Readthrough

(2014) Kim M. Keeling et al.   Annual Review of Genomics and Human Genetics

A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

(2014) Hila Gingold et al.   CELL

Cellular Differences in Protein Synthesis Regulate Tissue Homeostasis

(2014) Michael Buszczak et al.   CELL

Modulation of Stop Codon Read-Through Efficiency and Its Effect on the Replication of Murine Leukemia Virus

(2014) E. Csibra et al.   JOURNAL OF VIROLOGY

Emerging roles of tRNA in adaptive translation, signalling dynamics and disease

(2014) Sebastian Kirchner et al.   NATURE REVIEWS GENETICS

Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes

(2014) Sohail Khoshnevis et al.   NUCLEIC ACIDS RESEARCH

Evidence of efficient stop codon readthrough in four mammalian genes

(2014) Gary Loughran et al.   NUCLEIC ACIDS RESEARCH

New insights into the incorporation of natural suppressor tRNAs at stop codons in Saccharomyces cerevisiae

(2014) Sandra Blanchet et al.   NUCLEIC ACIDS RESEARCH

Diversity of human tRNA genes from the 1000-genomes project

(2014) Marc Parisien et al.   RNA Biology

Peroxisomal lactate dehydrogenase is generated by translational readthrough in mammals

(2014) Fabian Schueren et al.   eLife

U6 promoter-enhanced GlnUAG suppressor tRNA has higher suppression efficacy and can be stably expressed in 293 cells

(2013) Ramesh Koukuntla et al.   JOURNAL OF GENE MEDICINE

Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster

(2013) Joshua G Dunn et al.   eLife

L-MPZ, a Novel Isoform of Myelin P0, Is Produced by Stop Codon Readthrough

(2012) Yoshihide Yamaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-canonical translation in RNA viruses

(2012) A. E. Firth et al.   JOURNAL OF GENERAL VIROLOGY

Conservation of the relative tRNA composition in healthy and cancerous tissues

(2012) S. Mahlab et al.   RNA

Sense from nonsense: therapies for premature stop codon diseases

(2012) Laure Bidou et al.   TRENDS IN MOLECULAR MEDICINE

Statistical Analysis of Readthrough Levels for Nonsense Mutations in Mammalian Cells Reveals a Major Determinant of Response to Gentamicin

(2012) Célia Floquet et al.   PLoS Genetics

Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation

(2011) Pavel Ivanov et al.   MOLECULAR CELL

Stimulation of stop codon readthrough: frequent presence of an extended 3′ RNA structural element

(2011) Andrew E. Firth et al.   NUCLEIC ACIDS RESEARCH

RNA Interference and Cancer Therapy

(2011) Zhaohui Wang et al.   PHARMACEUTICAL RESEARCH

Characterization of the stop codon readthrough signal of Colorado tick fever virus segment 9 RNA

(2011) S. Napthine et al.   RNA

The C-Terminal Region of Eukaryotic Translation Initiation Factor 3a (eIF3a) Promotes mRNA Recruitment, Scanning, and, Together with eIF3j and the eIF3b RNA Recognition Motif, Selection of AUG Start Codons

(2010) W.-L. Chiu et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1

(2009) Yuehua Wei et al.   EMBO JOURNAL

tRNA over-expression in breast cancer and functional consequences

(2009) Mariana Pavon-Eternod et al.   NUCLEIC ACIDS RESEARCH

GtRNAdb: a database of transfer RNA genes detected in genomic sequence

(2008) P. P. Chan et al.   NUCLEIC ACIDS RESEARCH

Introducing sense into nonsense in treatments of human genetic diseases

(2008) Liat Linde et al.   TRENDS IN GENETICS