Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes

Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29

(2013) Yaser Hashem et al.   CELL

The initiation of mammalian protein synthesis and mRNA scanning mechanism

(2013) Ivan B. Lomakin et al.   NATURE

Architecture of Human Translation Initiation Factor 3

(2013) Jordi Querol-Audi et al.   STRUCTURE

Translation Initiation Factors eIF3 and HCR1 Control Translation Termination and Stop Codon Read-Through in Yeast Cells

(2013) Petra Beznosková et al.   PLoS Genetics

‘Ribozoomin’ – Translation Initiation from the Perspective of the Ribosome-bound Eukaryotic Initiation Factors (eIFs)

(2012) Leos Shivaya Valasek   CURRENT PROTEIN & PEPTIDE SCIENCE

Functional Characterization of the Role of the N-terminal Domain of the c/Nip1 Subunit of Eukaryotic Initiation Factor 3 (eIF3) in AUG Recognition

(2012) Martina Karásková et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin

(2012) Uwe Mueller et al.   JOURNAL OF SYNCHROTRON RADIATION

Sequential Eukaryotic Translation Initiation Factor 5 (eIF5) Binding to the Charged Disordered Segments of eIF4G and eIF2  Stabilizes the 48S Preinitiation Complex and Promotes Its Shift to the Initiation Mode

(2012) C. R. Singh et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex

(2012) Andrew M Ellisdon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

FastML: a web server for probabilistic reconstruction of ancestral sequences

(2012) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Small Ribosomal Protein RPS0 Stimulates Translation Initiation by Mediating 40S-Binding of eIF3 via Its Direct Contact with the eIF3a/TIF32 Subunit

(2012) Tomáš Kouba et al.   PLoS One

Novel insights into the architecture and protein interaction network of yeast eIF3

(2012) S. Khoshnevis et al.   RNA

Yeast eIF4B binds to the head of the 40S ribosomal subunit and promotes mRNA recruitment through its N-terminal and internal repeat domains

(2012) S. E. Walker et al.   RNA

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

The C-Terminal Domain of Eukaryotic Initiation Factor 5 Promotes Start Codon Recognition by Its Dynamic Interplay with eIF1 and eIF2β

(2012) Rafael E. Luna et al.   Cell Reports

Depletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wide

(2011) Eun-Hee Park et al.   BMC GENOMICS

Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly

(2011) Anna Herrmannová et al.   NUCLEIC ACIDS RESEARCH

The eIF3c/NIP1 PCI domain interacts with RNA and RACK1/ASC1 and promotes assembly of translation preinitiation complexes

(2011) Tomáš Kouba et al.   NUCLEIC ACIDS RESEARCH

The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together

(2011) G. R. Pathare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translation Reinitiation Relies on the Interaction between eIF3a/TIF32 and Progressively Folded cis-Acting mRNA Elements Preceding Short uORFs

(2011) Vanda Munzarová et al.   PLoS Genetics

Experimental phasing withSHELXC/D/E: combining chain tracing with density modification

(2010) George M. Sheldrick   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Multiple elements in the eIF4G1 N-terminus promote assembly of eIF4G1•PABP mRNPsin vivo

(2010) Eun-Hee Park et al.   EMBO JOURNAL

The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection

(2010) Latifa ElAntak et al.   JOURNAL OF MOLECULAR BIOLOGY

The RNA Recognition Motif of Eukaryotic Translation Initiation Factor 3g (eIF3g) Is Required for Resumption of Scanning of Posttermination Ribosomes for Reinitiation on GCN4 and Together with eIF3i Stimulates Linear Scanning

(2010) L. Cuchalova et al.   MOLECULAR AND CELLULAR BIOLOGY

The C-Terminal Region of Eukaryotic Translation Initiation Factor 3a (eIF3a) Promotes mRNA Recruitment, Scanning, and, Together with eIF3j and the eIF3b RNA Recognition Motif, Selection of AUG Start Codons

(2010) W.-L. Chiu et al.   MOLECULAR AND CELLULAR BIOLOGY

The 5′-7-Methylguanosine Cap on Eukaryotic mRNAs Serves Both to Stimulate Canonical Translation Initiation and to Block an Alternative Pathway

(2010) Sarah F. Mitchell et al.   MOLECULAR CELL

Functional Overlap between eIF4G Isoforms in Saccharomyces cerevisiae

(2010) Bryan K. Clarkson et al.   PLoS One

Crystal Structure of the RNA Recognition Motif of Yeast Translation Initiation Factor eIF3b Reveals Differences to Human eIF3b

(2010) Sohail Khoshnevis et al.   PLoS One

Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1

(2010) J. Rabl et al.   SCIENCE

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

PCI Complexes: Beyond the Proteasome, CSN, and eIF3 Troika

(2009) Elah Pick et al.   MOLECULAR CELL

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Accelerating and focusing protein-protein docking correlations using multi-dimensional rotational FFT generating functions

(2008) D. W. Ritchie et al.   BIOINFORMATICS

Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes

(2008) Andrey V Pisarev et al.   EMBO JOURNAL

eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA

(2008) B. Szamecz et al.   GENES & DEVELOPMENT

eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy

(2008) Francisco Ramírez-Valle et al.   JOURNAL OF CELL BIOLOGY

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

The Arabidopsis COP9 Signalosome Subunit 7 Is a Model PCI Domain Protein with Subdomains Involved in COP9 Signalosome Assembly

(2008) M. Dessau et al.   PLANT CELL