Thrombotic microangiopathy in aHUS and beyond: clinical clues from complement genetics
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Title
Thrombotic microangiopathy in aHUS and beyond: clinical clues from complement genetics
Authors
Keywords
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Journal
Nature Reviews Nephrology
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-05-05
DOI
10.1038/s41581-021-00424-4
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Note: Only part of the references are listed.- Pretransplant Genetic Susceptibility: Clinical Relevance in Transplant-Associated Thrombotic Microangiopathy
- (2020) Eleni Gavriilaki et al. THROMBOSIS AND HAEMOSTASIS
- The familial risk of developing atypical Hemolytic Uremic Syndrome.
- (2020) Emilia Arjona et al. BLOOD
- Eculizumab discontinuation in children and adults with atypical haemolytic uremic syndrome: a prospective multicentric study
- (2020) Fadi Fakhouri et al. BLOOD
- Atypical and secondary hemolytic uremic syndromes have a distinct presentation and no common genetic risk factors
- (2019) Alice Le Clech et al. KIDNEY INTERNATIONAL
- Impact of hypertensive emergency and complement rare variants on presentation and outcome of atypical hemolytic uremic syndrome
- (2019) Khalil El Karoui et al. HAEMATOLOGICA
- Etiology and Outcomes of Thrombotic Microangiopathies
- (2019) Guillaume Bayer et al. Clinical Journal of the American Society of Nephrology
- Complement Gene Variants and Shiga Toxin–Producing Escherichia coli–Associated Hemolytic Uremic Syndrome
- (2019) Véronique Frémeaux-Bacchi et al. Clinical Journal of the American Society of Nephrology
- An Ex Vivo Test of Complement Activation on Endothelium for Individualized Eculizumab Therapy in Hemolytic Uremic Syndrome
- (2019) Miriam Galbusera et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Placental sFLT1 is associated with complement activation and syncytiotrophoblast damage in preeclampsia
- (2019) Ai-ris Yonekura Collier et al. HYPERTENSION IN PREGNANCY
- Severe and malignant hypertension are common in primary atypical hemolytic uremic syndrome
- (2019) Teresa Cavero et al. KIDNEY INTERNATIONAL
- Clinical and Immunological Profile of Anti-factor H Antibody Associated Atypical Hemolytic Uremic Syndrome: A Nationwide Database
- (2019) Mamta Puraswani et al. Frontiers in Immunology
- Use of Highly Individualized Complement Blockade Has Revolutionized Clinical Outcomes after Kidney Transplantation and Renal Epidemiology of Atypical Hemolytic Uremic Syndrome
- (2019) Julien Zuber et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Complement Activation and Thrombotic Microangiopathies
- (2019) Marta Palomo et al. Clinical Journal of the American Society of Nephrology
- Diagnostic and Risk Factors for Complement Defects in Hypertensive Emergency and Thrombotic Microangiopathy
- (2019) Sjoerd A.M.E.G. Timmermans et al. HYPERTENSION
- Statistical Validation of Rare Complement Variants Provides Insights into the Molecular Basis of Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy
- (2018) Amy J. Osborne et al. JOURNAL OF IMMUNOLOGY
- C5b9 Formation on Endothelial Cells Reflects Complement Defects among Patients with Renal Thrombotic Microangiopathy and Severe Hypertension
- (2018) Sjoerd A.M.E.G. Timmermans et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome
- (2018) Ana Huerta et al. KIDNEY INTERNATIONAL
- Complete functional characterization of disease-associated genetic variants in the complement factor H gene
- (2018) Héctor Martín Merinero et al. KIDNEY INTERNATIONAL
- Clinical and genetic predictors of atypical hemolytic uremic syndrome phenotype and outcome
- (2018) Franz Schaefer et al. KIDNEY INTERNATIONAL
- Malignant hypertension
- (2018) Sébastien Rubin et al. JOURNAL OF HYPERTENSION
- Genetic Analysis of 400 Patients Refines Understanding and Implicates a New Gene in Atypical Hemolytic Uremic Syndrome
- (2018) Fengxiao Bu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Predictors of 5-year outcomes in malignant phase hypertension
- (2017) Alena Shantsila et al. JOURNAL OF HYPERTENSION
- The Phenotypic Spectrum of Nephropathies Associated with Mutations in Diacylglycerol Kinaseε
- (2017) Karolis Azukaitis et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Patients with hypertension-associated thrombotic microangiopathy may present with complement abnormalities
- (2017) Sjoerd A.M.E.G. Timmermans et al. KIDNEY INTERNATIONAL
- Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference
- (2017) Timothy H.J. Goodship et al. KIDNEY INTERNATIONAL
- Haemolytic uraemic syndrome
- (2017) Fadi Fakhouri et al. LANCET
- Genetic testing of complement and coagulation pathways in patients with severe hypertension and renal microangiopathy
- (2017) Christopher P Larsen et al. MODERN PATHOLOGY
- Suspected atypical haemolytic uraemic syndrome in two post-partum patients with foetal-death in utero responding to eculizumab
- (2017) Justin Chua et al. NEPHROLOGY
- Eculizumab in secondary atypical haemolytic uraemic syndrome
- (2017) Teresa Cavero et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Renal Cortical Necrosis in Postpartum Hemorrhage: A Case Series
- (2016) Marie Frimat et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Terminal Complement Inhibitor Eculizumab in Adult Patients With Atypical Hemolytic Uremic Syndrome: A Single-Arm, Open-Label Trial
- (2016) Fadi Fakhouri et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Pathogenic Variants in Complement Genes and Risk of Atypical Hemolytic Uremic Syndrome Relapse after Eculizumab Discontinuation
- (2016) Fadi Fakhouri et al. Clinical Journal of the American Society of Nephrology
- Direct evidence of complement activation in HELLP syndrome: A link to atypical hemolytic uremic syndrome
- (2016) Arthur J. Vaught et al. EXPERIMENTAL HEMATOLOGY
- Thrombotic Microangiopathy in Inverted Formin 2 – Mediated Renal Disease
- (2016) Rachel C. Challis et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Atypical haemolytic uraemic syndrome and pregnancy: outcome with ongoing eculizumab
- (2016) Aude Servais et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Discontinuation of Eculizumab Treatment in Atypical Hemolytic Uremic Syndrome: An Update
- (2015) Gianluigi Ardissino et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Discontinuation of Eculizumab Maintenance Treatment for Atypical Hemolytic Uremic Syndrome
- (2015) Jack F.M. Wetzels et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Soluble C5b-9 as a Biomarker for Complement Activation in Atypical Hemolytic Uremic Syndrome
- (2015) Fengxiao Bu et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- The genetic fingerprint of susceptibility for transplant-associated thrombotic microangiopathy
- (2015) S. Jodele et al. BLOOD
- Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
- (2015) Sue Richards et al. GENETICS IN MEDICINE
- Classical Complement Pathway Activation in the Kidneys of Women With PreeclampsiaNovelty and Significance
- (2015) Marlies Penning et al. HYPERTENSION
- Increasing Trend in Admissions for Malignant Hypertension and Hypertensive Encephalopathy in the United States
- (2015) L. A. Polgreen et al. HYPERTENSION
- Eculizumab in pregnancy-associated atypical hemolytic uremic syndrome: insights for optimizing management
- (2015) Erika De Sousa Amorim et al. JOURNAL OF NEPHROLOGY
- High-Throughput Genetic Testing for Thrombotic Microangiopathies and C3 Glomerulopathies
- (2015) F. Bu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Adult-onset renal thrombotic microangiopathy and pulmonary arterial hypertension in cobalamin C deficiency
- (2015) Steven Grangé et al. LANCET
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria
- (2015) Richard J. Kelly et al. NEW ENGLAND JOURNAL OF MEDICINE
- Loss of DGK induces endothelial cell activation and death independently of complement activation
- (2014) S. Bruneau et al. BLOOD
- Dynamics of complement activation in aHUS and how to monitor eculizumab therapy
- (2014) M. Noris et al. BLOOD
- Complement Factor B Mutations in Atypical Hemolytic Uremic Syndrome--Disease-Relevant or Benign?
- (2014) M. C. Marinozzi et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Insights From the Use in Clinical Practice of Eculizumab in Adult Patients With Atypical Hemolytic Uremic Syndrome Affecting the Native Kidneys: An Analysis of 19 Cases
- (2013) Fadi Fakhouri et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Successful Treatment of the Postpartum Atypical Hemolytic Uremic Syndrome With Eculizumab
- (2013) Stefan Zschiedrich et al. ANNALS OF INTERNAL MEDICINE
- Genetics and Outcome of Atypical Hemolytic Uremic Syndrome: A Nationwide French Series Comparing Children and Adults
- (2013) V. Fremeaux-Bacchi et al. Clinical Journal of the American Society of Nephrology
- Comprehensive Genetic Analysis of Complement and Coagulation Genes in Atypical Hemolytic Uremic Syndrome
- (2013) F. Bu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration
- (2013) Johanna M Seddon et al. NATURE GENETICS
- Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome
- (2013) Mathieu Lemaire et al. NATURE GENETICS
- Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome
- (2013) C.M. Legendre et al. NEW ENGLAND JOURNAL OF MEDICINE
- Determining the Population Frequency of the CFHR3/CFHR1 Deletion at 1q32
- (2013) Lucy V. Holmes et al. PLoS One
- Targeted strategies in the prevention and management of atypical HUS recurrence after kidney transplantation
- (2013) Julien Zuber et al. Transplantation Reviews
- A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function
- (2012) L. T. Roumenina et al. BLOOD
- The genetics of the alternative pathway of complement in the pathogenesis of HELLP syndrome
- (2012) Francesca Crovetto et al. Journal of Maternal-Fetal & Neonatal Medicine
- A Clinicopathologic Study of Thrombotic Microangiopathy in IgA Nephropathy
- (2011) K. El Karoui et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mutations in Complement Regulatory Proteins Predispose to Preeclampsia: A Genetic Analysis of the PROMISSE Cohort
- (2011) Jane E. Salmon et al. PLOS MEDICINE
- Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype
- (2010) M. Noris et al. Clinical Journal of the American Society of Nephrology
- Clinical Features of Anti-Factor H Autoantibody-Associated Hemolytic Uremic Syndrome
- (2010) M.-A. Dragon-Durey et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis
- (2010) Daniel P Gale et al. LANCET
- Improving Survival of Malignant Hypertension Patients Over 40 Years
- (2009) D. A. Lane et al. AMERICAN JOURNAL OF HYPERTENSION
- A novel mutation in the complement regulator clusterin in recurrent hemolytic uremic syndrome
- (2009) Anne-lie Ståhl et al. MOLECULAR IMMUNOLOGY
- Thrombomodulin Mutations in Atypical Hemolytic–Uremic Syndrome
- (2009) Mieke Delvaeye et al. NEW ENGLAND JOURNAL OF MEDICINE
- Complement Mutation-AssociatedDe NovoThrombotic Microangiopathy Following Kidney Transplantation
- (2008) M. Le Quintrec et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
- (2008) V. Fremeaux-Bacchi et al. BLOOD
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