Diagnostic and Risk Factors for Complement Defects in Hypertensive Emergency and Thrombotic Microangiopathy

Atypical and secondary hemolytic uremic syndromes have a distinct presentation and no common genetic risk factors

(2019) Alice Le Clech et al.   KIDNEY INTERNATIONAL

Impact of hypertensive emergency and complement rare variants on presentation and outcome of atypical hemolytic uremic syndrome

(2019) Khalil El Karoui et al.   HAEMATOLOGICA

An Ex Vivo Test of Complement Activation on Endothelium for Individualized Eculizumab Therapy in Hemolytic Uremic Syndrome

(2019) Miriam Galbusera et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Defects in complement and “secondary” hemolytic uremic syndrome

(2019) Sjoerd A.M.E.G. Timmermans et al.   KIDNEY INTERNATIONAL

Statistical Validation of Rare Complement Variants Provides Insights into the Molecular Basis of Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy

(2018) Amy J. Osborne et al.   JOURNAL OF IMMUNOLOGY

C5b9 Formation on Endothelial Cells Reflects Complement Defects among Patients with Renal Thrombotic Microangiopathy and Severe Hypertension

(2018) Sjoerd A.M.E.G. Timmermans et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Authors Reply

(2017) Sjoerd A.M.E.G. Timmermans et al.   KIDNEY INTERNATIONAL

Patients with hypertension-associated thrombotic microangiopathy may present with complement abnormalities

(2017) Sjoerd A.M.E.G. Timmermans et al.   KIDNEY INTERNATIONAL

Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

(2017) Timothy H.J. Goodship et al.   KIDNEY INTERNATIONAL

Genetic testing of complement and coagulation pathways in patients with severe hypertension and renal microangiopathy

(2017) Christopher P Larsen et al.   MODERN PATHOLOGY

Terminal Complement Inhibitor Eculizumab in Adult Patients With Atypical Hemolytic Uremic Syndrome: A Single-Arm, Open-Label Trial

(2016) Fadi Fakhouri et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Collapsing glomerulopathy is common in the setting of thrombotic microangiopathy of the native kidney

(2016) David Buob et al.   KIDNEY INTERNATIONAL

Effect of Blood Sampling, Processing, and Storage on the Measurement of Complement Activation Biomarkers

(2015) Shangbin Yang et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies

(2015) Christoph Licht et al.   KIDNEY INTERNATIONAL

An international consensus approach to the management of atypical hemolytic uremic syndrome in children

(2015) Chantal Loirat et al.   PEDIATRIC NEPHROLOGY

Dynamics of complement activation in aHUS and how to monitor eculizumab therapy

(2014) M. Noris et al.   BLOOD

Syndromes of Thrombotic Microangiopathy

(2014) James N. George et al.   NEW ENGLAND JOURNAL OF MEDICINE

Complement Genes Strongly Predict Recurrence and Graft Outcome in Adult Renal Transplant Recipients with Atypical Hemolytic and Uremic Syndrome

(2013) M. Le Quintrec et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Genetics and Outcome of Atypical Hemolytic Uremic Syndrome: A Nationwide French Series Comparing Children and Adults

(2013) V. Fremeaux-Bacchi et al.   Clinical Journal of the American Society of Nephrology

2013 ESH/ESC Guidelines for the management of arterial hypertension

(2013)   EUROPEAN HEART JOURNAL

Chronic kidney disease: global dimension and perspectives

(2013) Vivekanand Jha et al.   LANCET

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

(2013) C.M. Legendre et al.   NEW ENGLAND JOURNAL OF MEDICINE

Eculizumab for Atypical Hemolytic Uremic Syndrome Recurrence in Renal Transplantation

(2012) J. Zuber et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Safety and Complications of Percutaneous Kidney Biopsies in 715 Children and 8573 Adults in Norway 1988-2010

(2012) C. Tondel et al.   Clinical Journal of the American Society of Nephrology

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

(2010) M. Noris et al.   Clinical Journal of the American Society of Nephrology

The Development of Atypical Hemolytic Uremic Syndrome Depends on Complement C5

(2010) E. G. de Jorge et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Long-term renal survival in malignant hypertension

(2010) R. Gonzalez et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Predictive Features of Severe Acquired ADAMTS13 Deficiency in Idiopathic Thrombotic Microangiopathies: The French TMA Reference Center Experience

(2010) Paul Coppo et al.   PLoS One

Renal Thrombotic Microangiopathies Induced by Severe Hypertension

(2008) Bo ZHANG et al.   HYPERTENSION RESEARCH