Use of Highly Individualized Complement Blockade Has Revolutionized Clinical Outcomes after Kidney Transplantation and Renal Epidemiology of Atypical Hemolytic Uremic Syndrome

Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

(2017) Timothy H.J. Goodship et al.   KIDNEY INTERNATIONAL

Haemolytic uraemic syndrome

(2017) Fadi Fakhouri et al.   LANCET

Terminal Complement Inhibitor Eculizumab in Adult Patients With Atypical Hemolytic Uremic Syndrome: A Single-Arm, Open-Label Trial

(2016) Fadi Fakhouri et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Pathogenic Variants in Complement Genes and Risk of Atypical Hemolytic Uremic Syndrome Relapse after Eculizumab Discontinuation

(2016) Fadi Fakhouri et al.   Clinical Journal of the American Society of Nephrology

Defining the genetics of thrombotic microangiopathies

(2016) Paula Vieira-Martins et al.   TRANSFUSION AND APHERESIS SCIENCE

Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies

(2015) Christoph Licht et al.   KIDNEY INTERNATIONAL

A national specialized service in England for atypical haemolytic uraemic syndrome—the first year’s experience

(2015) N.S. Sheerin et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Discontinuation of Eculizumab Maintenance Treatment for Atypical Hemolytic Uremic Syndrome: A Report of 10 Cases

(2014) Gianluigi Ardissino et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Cryptic Activity of Atypical Hemolytic Uremic Syndrome and Eculizumab Treatment

(2014) M. Belingheri et al.   PEDIATRICS

Atypical Hemolytic Uremic Syndrome Recurrence After Kidney Transplantation

(2014) Dany Matar et al.   TRANSPLANTATION

Complement Genes Strongly Predict Recurrence and Graft Outcome in Adult Renal Transplant Recipients with Atypical Hemolytic and Uremic Syndrome

(2013) M. Le Quintrec et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Genetics and Outcome of Atypical Hemolytic Uremic Syndrome: A Nationwide French Series Comparing Children and Adults

(2013) V. Fremeaux-Bacchi et al.   Clinical Journal of the American Society of Nephrology

Combined Complement Gene Mutations in Atypical Hemolytic Uremic Syndrome Influence Clinical Phenotype

(2013) E. Bresin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome

(2013) Mathieu Lemaire et al.   NATURE GENETICS

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

(2013) C.M. Legendre et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeted strategies in the prevention and management of atypical HUS recurrence after kidney transplantation

(2013) Julien Zuber et al.   Transplantation Reviews

Eculizumab for Atypical Hemolytic Uremic Syndrome Recurrence in Renal Transplantation

(2012) J. Zuber et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies

(2012) Julien Zuber et al.   Nature Reviews Nephrology

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

(2010) M. Noris et al.   Clinical Journal of the American Society of Nephrology

New insights into postrenal transplant hemolytic uremic syndrome

(2010) Julien Zuber et al.   Nature Reviews Nephrology

Anti-Factor H Autoantibodies in a Fifth Renal Transplant Recipient with Atypical Hemolytic and Uremic Syndrome

(2009) M. Le Quintrec et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Atypical Hemolytic–Uremic Syndrome

(2009) Marina Noris et al.   NEW ENGLAND JOURNAL OF MEDICINE