Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release
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Title
Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release
Authors
Keywords
p300/CBP, deacetylases, acetylation, enhancer, bromodomain, BRD4, TFIID, pause release, PIC assembly, super-enhancer
Journal
MOLECULAR CELL
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-03-24
DOI
10.1016/j.molcel.2021.03.008
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Note: Only part of the references are listed.- Enhancers predominantly regulate gene expression during differentiation via transcription initiation
- (2021) Martin S.C. Larke et al. MOLECULAR CELL
- Using TTchem-seq for profiling nascent transcription and measuring transcript elongation
- (2020) Lea H. Gregersen et al. Nature Protocols
- KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain
- (2020) Michal Lipinski et al. Nature Communications
- Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis
- (2020) Zachary J. Milstone et al. Science Advances
- Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation
- (2019) Leighton Core et al. GENES & DEVELOPMENT
- Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming
- (2019) Ayyub Ebrahimi et al. Nature Chemical Biology
- Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells
- (2019) Jieru Li et al. CELL
- TAF1 plays a critical role in AML1-ETO driven leukemogenesis
- (2019) Ye Xu et al. Nature Communications
- EnrichedHeatmap: an R/Bioconductor package for comprehensive visualization of genomic signal associations
- (2018) Zuguang Gu et al. BMC GENOMICS
- Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome
- (2018) Brian T. Weinert et al. CELL
- The dTAG system for immediate and target-specific protein degradation
- (2018) Behnam Nabet et al. Nature Chemical Biology
- Born to run: control of transcription elongation by RNA polymerase II
- (2018) Fei Xavier Chen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis
- (2018) Matthias Muhar et al. SCIENCE
- Coactivator condensation at super-enhancers links phase separation and gene control
- (2018) Benjamin R. Sabari et al. SCIENCE
- Mediator and RNA polymerase II clusters associate in transcription-dependent condensates
- (2018) Won-Ki Cho et al. SCIENCE
- Early metazoan cell type diversity and the evolution of multicellular gene regulation
- (2018) Arnau Sebé-Pedrós et al. Nature Ecology & Evolution
- TissueEnrich: Tissue-specific gene enrichment analysis
- (2018) Ashish Jain et al. BIOINFORMATICS
- Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
- (2018) Ann Boija et al. CELL
- Structure of human TFIID and mechanism of TBP loading onto promoter DNA
- (2018) Avinash B. Patel et al. SCIENCE
- Performance Evaluation of the Q Exactive HF-X for Shotgun Proteomics
- (2017) Christian D. Kelstrup et al. JOURNAL OF PROTEOME RESEARCH
- Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
- (2017) Loren M. Lasko et al. NATURE
- An atlas of human long non-coding RNAs with accurate 5′ ends
- (2017) Chung-Chau Hon et al. NATURE
- Transcription regulation by the Mediator complex
- (2017) Julie Soutourina NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The MaxQuant computational platform for mass spectrometry-based shotgun proteomics
- (2016) Stefka Tyanova et al. Nature Protocols
- BET Bromodomain Inhibition Releases the Mediator Complex from Select cis -Regulatory Elements
- (2016) Anand S. Bhagwat et al. Cell Reports
- ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization
- (2015) Guangchuang Yu et al. BIOINFORMATICS
- Structural basis of transcription initiation by RNA polymerase II
- (2015) Sarah Sainsbury et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- dbSUPER: a database of super-enhancers in mouse and human genome
- (2015) Aziz Khan et al. NUCLEIC ACIDS RESEARCH
- Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium
- (2015) Nancy Yiu-Lin Yu et al. NUCLEIC ACIDS RESEARCH
- Transcription Factor Competition Allows Embryonic Stem Cells to Distinguish Authentic Signals from Noise
- (2015) Cameron Sokolik et al. Cell Systems
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases
- (2014) Li Shen et al. BMC GENOMICS
- Rapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer
- (2014) Christian D. Kelstrup et al. JOURNAL OF PROTEOME RESEARCH
- Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
- (2013) Jakob Lovén et al. CELL
- Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition
- (2013) Feng Wang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Modification of Enhancer Chromatin: What, How, and Why?
- (2013) Eliezer Calo et al. MOLECULAR CELL
- Topology of mammalian developmental enhancers and their regulatory landscapes
- (2013) Wouter de Laat et al. NATURE
- Regulation of nucleosome dynamics by histone modifications
- (2013) Gabriel E Zentner et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition
- (2013) Jose P. Lopez-Atalaya et al. NUCLEIC ACIDS RESEARCH
- Multivalent Engagement of TFIID to Nucleosomes
- (2013) Rick van Nuland et al. PLoS One
- Lysine Succinylation Is a Frequently Occurring Modification in Prokaryotes and Eukaryotes and Extensively Overlaps with Acetylation
- (2013) Brian T. Weinert et al. Cell Reports
- H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation
- (2013) Ji-Eun Lee et al. eLife
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration
- (2012) H. Thorvaldsdottir et al. BRIEFINGS IN BIOINFORMATICS
- Differential oestrogen receptor binding is associated with clinical outcome in breast cancer
- (2012) Caryn S. Ross-Innes et al. NATURE
- Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
- (2012) Warren A. Whyte et al. NATURE
- Transcription factors: from enhancer binding to developmental control
- (2012) François Spitz et al. NATURE REVIEWS GENETICS
- Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
- (2012) Karen Adelman et al. NATURE REVIEWS GENETICS
- Fast and accurate long-read alignment with Burrows–Wheeler transform
- (2010) Heng Li et al. BIOINFORMATICS
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Widespread transcription at neuronal activity-regulated enhancers
- (2010) Tae-Kyung Kim et al. NATURE
- A unique chromatin signature uncovers early developmental enhancers in humans
- (2010) Alvaro Rada-Iglesias et al. NATURE
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
- (2010) Sohail Malik et al. NATURE REVIEWS GENETICS
- Histone H3K27ac separates active from poised enhancers and predicts developmental state
- (2010) M. P. Creyghton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CBP and p300 are essential for renin cell identity and morphological integrity of the kidney
- (2009) R. Ariel Gomez et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- A clustering approach for identification of enriched domains from histone modification ChIP-Seq data
- (2009) Chongzhi Zang et al. BIOINFORMATICS
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes
- (2009) Zhibin Wang et al. CELL
- CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing
- (2009) F. Tie et al. DEVELOPMENT
- Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
- (2008) Aleksey G. Kazantsev et al. NATURE REVIEWS DRUG DISCOVERY
- Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300
- (2008) Lei Zeng et al. STRUCTURE
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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