Design of an Injectable Polypeptide Hydrogel Depot Containing the Immune Checkpoint Blocker Anti‐PD‐L1 and Doxorubicin to Enhance Antitumor Combination Therapy

Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses

(2020) Yu Chao et al.   Science Advances

Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker–based immunotherapy

(2020) Feihu Wang et al.   Science Advances

Synergistic tumor immunological strategy by combining tumor nanovaccine with gene-mediated extracellular matrix scavenger

(2020) Yingying Hu et al.   BIOMATERIALS

Sustained release of lipophilic gemcitabine from an injectable polymeric hydrogel for synergistically enhancing tumor chemoradiotherapy

(2020) Xiaowei Yang et al.   CHEMICAL ENGINEERING JOURNAL

Nanoengineered Immune Niches for Reprogramming the Immunosuppressive Tumor Microenvironment and Enhancing Cancer Immunotherapy

(2019) Hathaichanok Phuengkham et al.   ADVANCED MATERIALS

Advances in drug delivery for post-surgical cancer treatment

(2019) Lin-Lin Bu et al.   BIOMATERIALS

Anti-tumor potential of astragalus polysaccharides on breast cancer cell line mediated by macrophage activation

(2019) Wenfang Li et al.   Materials Science & Engineering C-Materials for Biological Applications

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

Smart Injectable Hydrogels for Cancer Immunotherapy

(2019) Yu Chao et al.   ADVANCED FUNCTIONAL MATERIALS

Combretastatin A4 Nanodrug‐Induced MMP9 Amplification Boosts Tumor‐Selective Release of Doxorubicin Prodrug

(2019) Jian Jiang et al.   ADVANCED MATERIALS

Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence

(2019) Chanyoung Song et al.   Nature Communications

Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

(2019) Liping Huang et al.   Nature Communications

The potentiated checkpoint blockade immunotherapy by ROS-responsive nanocarrier-mediated cascade chemo-photodynamic therapy

(2019) Liqin Hu et al.   BIOMATERIALS

Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade

(2018) Shuangjiang Yu et al.   ADVANCED MATERIALS

Anti-cancer therapy with TNFα and IFNγ: A comprehensive review

(2018) Jing Shen et al.   CELL PROLIFERATION

Tumor microenvironment-responsive hyaluronate-calcium carbonate hybrid nanoparticle enables effective chemotherapy for primary and advanced osteosarcomas

(2018) Yi Zhang et al.   Nano Research

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

(2018) Chao Wang et al.   Science Translational Medicine

Tackling Cancer Resistance by Immunotherapy: Updated Clinical Impact and Safety of PD-1/PD-L1 Inhibitors

(2018) Shifaa Abdin et al.   Cancers

Toward Biomaterials for Enhancing Immune Checkpoint Blockade Therapy

(2018) Qin Fan et al.   ADVANCED FUNCTIONAL MATERIALS

Semi-bald Micelles and Corresponding Percolated Micelle Networks of Thermogels

(2018) Shuquan Cui et al.   MACROMOLECULES

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review

(2018) Bagher Farhood et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Injectable Hydrogels as Unique Platforms for Local Chemotherapeutics-Based Combination Antitumor Therapy

(2018) Shuangjiang Yu et al.   MACROMOLECULAR BIOSCIENCE

Tumor Mutational Burden and Response Rate to PD-1 Inhibition

(2017) Mark Yarchoan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade

(2016) Haidong Tang et al.   CANCER CELL

Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy

(2016) Christina Pfirschke et al.   IMMUNITY

Rational design of ABC triblock terpolymer solution nanostructures with controlled patch morphology

(2016) Tina I. Löbling et al.   Nature Communications

Thermosensitive Polypeptide Hydrogels as a Platform for ROS-Triggered Cargo Release with Innate Cytoprotective Ability under Oxidative Stress

(2016) Qinghua Xu et al.   Advanced Healthcare Materials

Designing hydrogels for controlled drug delivery

(2016) Jianyu Li et al.   Nature Reviews Materials

Feasibility of a subcutaneously administered block/homo-mixed polyplex micelle as a carrier for DNA vaccination in a mouse tumor model

(2015) Lin Cui et al.   JOURNAL OF CONTROLLED RELEASE

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Hydrogels and Scaffolds for Immunomodulation

(2014) Ankur Singh et al.   ADVANCED MATERIALS

Thermosensitive hydrogels based on polypeptides for localized and sustained delivery of anticancer drugs

(2013) Yilong Cheng et al.   BIOMATERIALS

High-throughput sequencing of T-cell receptors reveals a homogeneous repertoire of tumour-infiltrating lymphocytes in ovarian cancer

(2013) Ryan O Emerson et al.   JOURNAL OF PATHOLOGY

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Biodegradable Thermogels

(2011) Min Hee Park et al.   ACCOUNTS OF CHEMICAL RESEARCH

Injectable hydrogels as unique biomedical materials

(2008) Lin Yu et al.   CHEMICAL SOCIETY REVIEWS

In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery

(2008) Chaoliang He et al.   JOURNAL OF CONTROLLED RELEASE

Novel temperature- and pH-responsive graft copolymers composed of poly(L-glutamic acid) and poly(N-isopropylacrylamide)

(2008) Chaoliang He et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Polymeric nanomedicine for cancer therapy

(2007) Jae Hyung Park et al.   PROGRESS IN POLYMER SCIENCE