RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators

EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation

(2019) Laurie Herviou et al.   LEUKEMIA

Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS

(2019) Matthieu Gratia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle

(2019) Shivana M. Lightman et al.   Frontiers in Immunology

R Loops: From Physiological to Pathological Roles

(2019) Tatiana García-Muse et al.   CELL

An R-loop-initiated CSB–RAD52–POLD3 pathway suppresses ROS-induced telomeric DNA breaks

(2019) Jun Tan et al.   NUCLEIC ACIDS RESEARCH

Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments

(2018) Hongwei Liao et al.   EMBO REPORTS

BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma

(2018) Guilhem Requirand et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

A single transcription factor is sufficient to induce and maintain secretory cell architecture

(2017) Hei-Yong G. Lo et al.   GENES & DEVELOPMENT

RECQ-like helicases Sgs1 and BLM regulate R-loop–associated genome instability

(2017) Emily Yun-Chia Chang et al.   JOURNAL OF CELL BIOLOGY

RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma

(2017) E Viziteu et al.   LEUKEMIA

Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell

(2017) Alboukadel Kassambara et al.   NUCLEIC ACIDS RESEARCH

MIST1 Links Secretion and Stress as both Target and Regulator of the Unfolded Protein Response

(2016) David A. Hess et al.   MOLECULAR AND CELLULAR BIOLOGY

ReactomePA: an R/Bioconductor package for reactome pathway analysis and visualization

(2016) Guangchuang Yu et al.   Molecular BioSystems

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

(2015) Wei Shi et al.   NATURE IMMUNOLOGY

A Systems Biology Approach Identifies a Regulatory Network in Parotid Acinar Cell Terminal Differentiation

(2015) Melissa A. Metzler et al.   PLoS One

Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells

(2015) Gersende Caron et al.   Cell Reports

IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV

(2014) M Grusdat et al.   CELL DEATH AND DIFFERENTIATION

IL-6 supports the generation of human long-lived plasma cells in combination with either APRIL or stromal cell-soluble factors

(2014) M Jourdan et al.   LEUKEMIA

SPIB and BATF provide alternate determinants of IRF4 occupancy in diffuse large B-cell lymphoma linked to disease heterogeneity

(2014) Matthew A. Care et al.   NUCLEIC ACIDS RESEARCH

Why Proteasome Inhibitors Cannot ERADicate Multiple Myeloma

(2013) Robert Z. Orlowski   CANCER CELL

Xbp1s-Negative Tumor B Cells and Pre-Plasmablasts Mediate Therapeutic Proteasome Inhibitor Resistance in Multiple Myeloma

(2013) Chungyee Leung-Hagesteijn et al.   CANCER CELL

A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

(2013) Giang Huong Nguyen et al.   CHEMISTRY & BIOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

In Vitro Generation of Long-lived Human Plasma Cells

(2012) M. Cocco et al.   JOURNAL OF IMMUNOLOGY

A gene expression signature for high-risk multiple myeloma

(2012) R Kuiper et al.   LEUKEMIA

BATF–JUN is critical for IRF4-mediated transcription in T cells

(2012) Peng Li et al.   NATURE

Studying and modelling dynamic biological processes using time-series gene expression data

(2012) Ziv Bar-Joseph et al.   NATURE REVIEWS GENETICS

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2

(2011) M. Watanabe-Matsui et al.   BLOOD

Characterization of a Transitional Preplasmablast Population in the Process of Human B Cell to Plasma Cell Differentiation

(2011) Michel Jourdan et al.   JOURNAL OF IMMUNOLOGY

Redox Remodeling Allows and Controls B-Cell Activation and Differentiation

(2010) Roberta Vené et al.   ANTIOXIDANTS & REDOX SIGNALING

XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum

(2010) Won Jae Huh et al.   GASTROENTEROLOGY

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

(2010) J. Moreaux et al.   HAEMATOLOGICA

Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells

(2010) Benjamin J. Capoccia et al.   PHYSIOLOGICAL GENOMICS

An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization

(2009) M. Jourdan et al.   BLOOD

A census of human transcription factors: function, expression and evolution

(2009) Juan M. Vaquerizas et al.   NATURE REVIEWS GENETICS