Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation

(2016) Martina Minnich et al.   NATURE IMMUNOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database

(2015) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

GenomicScape: An Easy-to-Use Web Tool for Gene Expression Data Analysis. Application to Investigate the Molecular Events in the Differentiation of B Cells into Plasma Cells

(2015) Alboukadel Kassambara et al.   PLoS Computational Biology

The microRNA-15 family inhibits the TGFβ-pathway in the heart

(2014) Anke J. Tijsen et al.   CARDIOVASCULAR RESEARCH

MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress

(2014) M. Rosenbaum et al.   GENES & DEVELOPMENT

Transgenic Mice Expressing Dominant-Negative Bright Exhibit Defects in B1 B Cells

(2014) J. C. Nixon et al.   JOURNAL OF IMMUNOLOGY

Transcription Elongation Factor ELL2 Drives Ig Secretory-Specific mRNA Production and the Unfolded Protein Response

(2014) Kyung Soo Park et al.   JOURNAL OF IMMUNOLOGY

miR-106b modulates cancer stem cell characteristics through TGF-β/Smad signaling in CD44-positive gastric cancer cells

(2014) Dayeon Yu et al.   LABORATORY INVESTIGATION

IL-6 supports the generation of human long-lived plasma cells in combination with either APRIL or stromal cell-soluble factors

(2014) M Jourdan et al.   LEUKEMIA

The Transcriptional Repressor ZBTB4 Regulates EZH2 Through a MicroRNA-ZBTB4-Specificity Protein Signaling Axis

(2014) Won Seok Yang et al.   NEOPLASIA

Targeting miR-21 Inhibits In Vitro and In Vivo Multiple Myeloma Cell Growth

(2013) E. Leone et al.   CLINICAL CANCER RESEARCH

Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia

(2013) M. Lionetti et al.   CLINICAL CANCER RESEARCH

miR-106b Fine Tunes ATG16L1 Expression and Autophagic Activity in Intestinal Epithelial HCT116 Cells

(2013) Zili Zhai et al.   INFLAMMATORY BOWEL DISEASES

Plasma cells require autophagy for sustainable immunoglobulin production

(2013) Niccolò Pengo et al.   NATURE IMMUNOLOGY

Androgen receptor and microRNA-21 axis downregulates transforming growth factor beta receptor II (TGFBR2) expression in prostate cancer

(2013) S Mishra et al.   ONCOGENE

MiR-21/Smad 7 signaling determines TGF-β1-induced CAF formation

(2013) Qiong Li et al.   Scientific Reports

Joint analysis of miRNA and mRNA expression data

(2012) A. Muniategui et al.   BRIEFINGS IN BIOINFORMATICS

MiR-20a and miR-106b negatively regulate autophagy induced by leucine deprivation via suppression of ULK1 expression in C2C12 myoblasts

(2012) Hao Wu et al.   CELLULAR SIGNALLING

Differential regulation of miR-21 and miR-146a by Epstein–Barr virus-encoded EBNA2

(2012) P Rosato et al.   LEUKEMIA

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

The miR-106b-25 cluster targets Smad7, activates TGF-β signaling and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer

(2012) A L Smith et al.   ONCOGENE

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

(2011) Jianxiang Chi et al.   Biology Direct

Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival

(2011) R. M. Reijmers et al.   BLOOD

Down-regulation of the cyclin E1 oncogene expression by microRNA-16-1 induces cell cycle arrest in human cancer cells

(2011) Fu Wang et al.   BMB Reports

MicroRNA-21: A novel therapeutic target in human cancer

(2011) Xuan Pan et al.   CANCER BIOLOGY & THERAPY

Characterization of a Transitional Preplasmablast Population in the Process of Human B Cell to Plasma Cell Differentiation

(2011) Michel Jourdan et al.   JOURNAL OF IMMUNOLOGY

The ARID Family Transcription Factor Bright Is Required for both Hematopoietic Stem Cell and B Lineage Development

(2011) C. F. Webb et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNAs as Regulators of Differentiation and Cell Fate Decisions

(2010) Kathryn N. Ivey et al.   Cell Stem Cell

Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling

(2010) Meidan Goldfinger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

(2010) J. Moreaux et al.   HAEMATOLOGICA

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling

(2010) N C Gutiérrez et al.   LEUKEMIA

High-risk myeloma is associated with global elevation of miRNAs and overexpression ofEIF2C2/AGO2

(2010) Yiming Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMPRII is a direct target of miR-21

(2009) W. Qin et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma

(2009) M. Lionetti et al.   BLOOD

An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization

(2009) M. Jourdan et al.   BLOOD

Patterns of microRNA expression characterize stages of human B-cell differentiation

(2009) Jenny Zhang et al.   BLOOD

gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis

(2009) M. Staron et al.   BLOOD

Endoplasmic reticulum HSP90b1 (gp96, grp94) optimizes B-cell function via chaperoning integrin and TLR but not immunoglobulin

(2008) B. Liu et al.   BLOOD

miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes

(2008) Q. Liu et al.   NUCLEIC ACIDS RESEARCH

miRecords: an integrated resource for microRNA-target interactions

(2008) F. Xiao et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death

(2008) R Schickel et al.   ONCOGENE

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

(2008) F. Pichiorri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA