Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice

IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs

(2015) Francesca Barone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-22: A likely target for treatment of autoimmune diseases

(2014) Xuyan Yang et al.   AUTOIMMUNITY REVIEWS

Endogenous IL-22 Plays a Dual Role in Arthritis: Regulation of Established Arthritis via IFN-γ Responses

(2014) Shivali Justa et al.   PLoS One

Homeostatic IL-23 receptor signaling limits Th17 response through IL-22-mediated containment of commensal microbiota

(2014) V. F.-S. Shih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation

(2014) Antonio P Baptista et al.   eLife

IL-17/Th17 mediated synovial inflammation is IL-22 independent

(2013) Jan Piet van Hamburg et al.   ANNALS OF THE RHEUMATIC DISEASES

Germinal Center Centroblasts Transition to a Centrocyte Phenotype According to a Timed Program and Depend on the Dark Zone for Effective Selection

(2013) Oliver Bannard et al.   IMMUNITY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

TH17 and TH22 cells: A confusion of antimicrobial response with tissue inflammation versus protection

(2012) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks

(2012) Deepali Malhotra et al.   NATURE IMMUNOLOGY

Increased Frequencies of Th22 Cells as well as Th17 Cells in the Peripheral Blood of Patients with Ankylosing Spondylitis and Rheumatoid Arthritis

(2012) Lei Zhang et al.   PLoS One

Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria

(2012) G. F. Sonnenberg et al.   SCIENCE

Innate IL-17 and IL-22 responses to enteric bacterial pathogens

(2012) Stephen J. Rubino et al.   TRENDS IN IMMUNOLOGY

Functional role of IL-22 in psoriatic arthritis

(2012) Anupam Mitra et al.   ARTHRITIS RESEARCH & THERAPY

Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation

(2011) Renoud J. Marijnissen et al.   ARTHRITIS AND RHEUMATISM

Interleukin-22 promotes osteoclastogenesis in rheumatoid arthritis through induction of RANKL in human synovial fibroblasts

(2011) Kyoung-Woon Kim et al.   ARTHRITIS AND RHEUMATISM

Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival

(2011) R. M. Reijmers et al.   BLOOD

Activation and effector functions of human RORC+ innate lymphoid cells

(2011) Ferry Cornelissen et al.   CURRENT OPINION IN IMMUNOLOGY

Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers

(2011) Xiaoming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The development of inducible bronchus-associated lymphoid tissue depends on IL-17

(2011) Javier Rangel-Moreno et al.   NATURE IMMUNOLOGY

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

(2010) J. P. van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A

(2010) Gregory F. Sonnenberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Overrepresentation of IL-17A and IL-22 Producing CD8 T Cells in Lesional Skin Suggests Their Involvement in the Pathogenesis of Psoriasis

(2010) Pieter C. M. Res et al.   PLoS One

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

(2009) Hui Shen et al.   ARTHRITIS AND RHEUMATISM

Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

(2009) Lies Geboes et al.   ARTHRITIS AND RHEUMATISM

1,25-dihydroxyvitamin D3modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis

(2009) E. M. Colin et al.   ARTHRITIS AND RHEUMATISM

Genetics of rheumatoid arthritis: Underlying evidence of ethnic differences

(2009) Yuta Kochi et al.   JOURNAL OF AUTOIMMUNITY

Murine NKT cells produce Th17 cytokine interleukin-22

(2008) Megumi Goto et al.   CELLULAR IMMUNOLOGY

Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease

(2008) Lauren A. Zenewicz et al.   IMMUNITY

Linking genetic susceptibility to Crohnʼs disease with Th17 cell function: IL-22 serum levels are increased in Crohnʼs disease and correlate with disease activity and IL23R genotype status

(2007) Silke Schmechel et al.   INFLAMMATORY BOWEL DISEASES