Tuberculosis: An Overview of the Immunogenic Response, Disease Progression, and Medicinal Chemistry Efforts in the Last Decade toward the Development of Potential Drugs for Extensively Drug-Resistant Tuberculosis Strains
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Tuberculosis: An Overview of the Immunogenic Response, Disease Progression, and Medicinal Chemistry Efforts in the Last Decade toward the Development of Potential Drugs for Extensively Drug-Resistant Tuberculosis Strains
Authors
Keywords
-
Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 64, Issue 8, Pages 4359-4395
Publisher
American Chemical Society (ACS)
Online
2021-04-15
DOI
10.1021/acs.jmedchem.0c01833
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis
- (2020) Wenting Zhao et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Treatment of Highly Drug-Resistant Pulmonary Tuberculosis
- (2020) Francesca Conradie et al. NEW ENGLAND JOURNAL OF MEDICINE
- Therapeutic Nanoparticles and Their Targeted Delivery Applications
- (2020) Abuzer Alp Yetisgin et al. MOLECULES
- Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol
- (2020) Lu Zhang et al. SCIENCE
- Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis
- (2020) Hongyi Zhao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Highly Potent and Selective N-aryl Oxamic Acid Based Inhibitors for Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (mPTPB)
- (2020) Kasi Viswanatharaju Ruddraraju et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline
- (2020) Hui Guo et al. NATURE
- Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II
- (2019) Wei Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- In vitro activity of DNF-3 against drug resistant Mycobacterium tuberculosis
- (2019) Md Imtiazul Islam et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Novel 1,3,4-oxadiazoles as antitubercular agents with limited activity against drug-resistant tuberculosis
- (2019) Vitthal B Makane et al. Future Medicinal Chemistry
- Structure-based design, synthesis and biological evaluation of a newer series of pyrazolo[1,5-a]pyrimidine analogues as potential anti-tubercular agents
- (2019) Palmi Modi et al. BIOORGANIC CHEMISTRY
- Structure of a bacterial ATP synthase
- (2019) Hui Guo et al. eLife
- Design and Synthesis of 2-Amino-thiophene-proline-conjugates and Their Anti-tubercular Activity against Mycobacterium Tuberculosis H37Ra
- (2019) Sachin B. Baravkar et al. ChemistrySelect
- Azaaurones as Potent Antimycobacterial Agents Active against MDR‐ and XDR‐TB
- (2019) André Campaniço et al. ChemMedChem
- Exploiting chitosan and gold nanoparticles for antimycobacterial activity of in silico identified antimicrobial motif of human neutrophil peptide-1
- (2019) Richa Sharma et al. Scientific Reports
- Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs
- (2019) Jody E. Phelan et al. Genome Medicine
- Mycobacterium tuberculosis Metabolism
- (2019) Gabriel T. Mashabela et al. Microbiology Spectrum
- The effects of diabetes on tuberculosis treatment outcomes: an updated systematic review and meta-analysis
- (2019) P. Huangfu et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Epidemiology of tuberculous lymphadenitis in Denmark: A nationwide register-based study
- (2019) Victor Dahl Mathiasen et al. PLoS One
- Spray-Dried, Nanoencapsulated, Multi-Drug Anti-Tuberculosis Therapy Aimed at Once Weekly Administration for the Duration of Treatment
- (2019) Lonji Kalombo et al. Nanomaterials
- The Anti-Mycobacterial Activity Of Ag, ZnO, And Ag- ZnO Nanoparticles Against MDR- And XDR-Mycobacterium tuberculosis
- (2019) Mohsen Heidary et al. Infection and Drug Resistance
- Comparison of in vitro activity and MIC distributions between the novel oxazolidinone delpazolid and linezolid against multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis in China
- (2018) Zhaojing Zong et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis
- (2018) Wei Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mycobacterium tuberculosis: Active disease and latent infection in a renal transplant cohort
- (2018) Nastaran Rafiei et al. NEPHROLOGY
- Novel compounds targeting InhA for TB therapy
- (2018) Manaf AlMatar et al. Pharmacological Reports
- Antimicrobial peptides as an alternative to anti-tuberculosis drugs
- (2018) Manaf AlMatar et al. PHARMACOLOGICAL RESEARCH
- Ionophoric effects of the antitubercular drug bedaquiline
- (2018) Kiel Hards et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mannose-capped lipoarabinomannan in Mycobacterium tuberculosis pathogenesis
- (2018) Joanne Turner et al. Pathogens and Disease
- Efficient analoging around ethionamide to explore thioamides bioactivation pathways triggered by boosters in Mycobacterium tuberculosis
- (2018) Marion Prieri et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Challenges of TB and HIV co-treatment
- (2018) Jeffrey A. Tornheim et al. Current Opinion in HIV and AIDS
- Nano based drug delivery systems: recent developments and future prospects
- (2018) Jayanta Kumar Patra et al. JOURNAL OF NANOBIOTECHNOLOGY
- Effect of Moxifloxacin plus Pretomanid against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay
- (2018) Carolina de Miranda Silva et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- CitE Enzymes Are Essential for Mycobacterium tuberculosis to Establish Infection in Macrophages and Guinea Pigs
- (2018) Garima Arora et al. Frontiers in Cellular and Infection Microbiology
- Pyrazolo[1,5-a]pyridine-3-carboxamide hybrids: Design, synthesis and evaluation of anti-tubercular activity
- (2017) Xiaoyun Lu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Drivers of Tuberculosis Transmission
- (2017) Barun Mathema et al. JOURNAL OF INFECTIOUS DISEASES
- What We Know About Tuberculosis Transmission: An Overview
- (2017) Gavin Churchyard et al. JOURNAL OF INFECTIOUS DISEASES
- Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis
- (2017) Subramanyam J. Tantry et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel Anti-Tuberculosis Nanodelivery Formulation of Ethambutol with Graphene Oxide
- (2017) Bullo Saifullah et al. MOLECULES
- Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance
- (2017) Abigail L Manson et al. NATURE GENETICS
- Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection
- (2017) Lucy C. K. Bell et al. NATURE REVIEWS MICROBIOLOGY
- Pulmonary Tuberculosis: Role of Radiology in Diagnosis and Management
- (2017) Arun C. Nachiappan et al. RADIOGRAPHICS
- Recent controversies about MDR and XDR-TB: Global implementation of the WHO shorter MDR-TB regimen and bedaquiline for all with MDR-TB?
- (2017) Keertan Dheda et al. RESPIROLOGY
- GeneXpert technology. A breakthrough for the diagnosis of tuberculous pericarditis and pleuritis in less than 2 hours
- (2017) Muhammad Saeed et al. SAUDI MEDICAL JOURNAL
- Atomic model for the dimeric FOregion of mitochondrial ATP synthase
- (2017) Hui Guo et al. SCIENCE
- Reversion of antibiotic resistance inMycobacterium tuberculosisby spiroisoxazoline SMARt-420
- (2017) Nicolas Blondiaux et al. SCIENCE
- Integrating Lung Physiology, Immunology, and Tuberculosis
- (2017) Jordi B. Torrelles et al. TRENDS IN MICROBIOLOGY
- Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant Mycobacterium tuberculosis
- (2017) Xiaoyun Lu et al. MedChemComm
- Targeting Energy Metabolism in Mycobacterium tuberculosis , a New Paradigm in Antimycobacterial Drug Discovery
- (2017) Dirk Bald et al. mBio
- Discovery of Fluorine-Containing Benzoxazinyl-oxazolidinones for the Treatment of Multidrug Resistant Tuberculosis
- (2017) Hongyi Zhao et al. ACS Medicinal Chemistry Letters
- Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis
- (2017) Mariana Rillo Sato et al. Drug Design Development and Therapy
- The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
- (2017) Keertan Dheda et al. Lancet Respiratory Medicine
- Malnutrition: Modulator of Immune Responses in Tuberculosis
- (2017) Padmapriyadarsini Chandrasekaran et al. Frontiers in Immunology
- Bolstering Immunity through Pattern Recognition Receptors: A Unique Approach to Control Tuberculosis
- (2017) Susanta Pahari et al. Frontiers in Immunology
- What Have We Learnt about BCG Vaccination in the Last 20 Years?
- (2017) Hazel M. Dockrell et al. Frontiers in Immunology
- Diabetes mellitus and the risk of multidrug resistant tuberculosis: a meta-analysis
- (2017) Qianqian Liu et al. Scientific Reports
- Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface
- (2017) Katherine A. Abrahams et al. Scientific Reports
- Targeting Antibiotic Resistance
- (2016) Mathieu F. Chellat et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Antibiotic resistance mechanisms in M. tuberculosis: an update
- (2016) Liem Nguyen ARCHIVES OF TOXICOLOGY
- Synthesis, biological evaluation and molecular docking study of some novel indole and pyridine based 1,3,4-oxadiazole derivatives as potential antitubercular agents
- (2016) N.C. Desai et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Antimicrobial peptides as novel anti-tuberculosis therapeutics
- (2016) João P. Silva et al. BIOTECHNOLOGY ADVANCES
- Linezolid in the treatment of drug-resistant tuberculosis: the challenge of its narrow therapeutic index
- (2016) Sean Wasserman et al. Expert Review of Anti-Infective Therapy
- A study on pre-XDR & XDR tuberculosis & their prevalent genotypes in clinical isolates of Mycobacterium tuberculosis in north India
- (2016) Amita Jain et al. INDIAN JOURNAL OF MEDICAL RESEARCH
- Drug-Resistant Tuberculosis
- (2016) Sebastian G. Kurz et al. INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
- Delamanid in the treatment of multidrug-resistant tuberculosis
- (2016) R. Gupta et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis
- (2016) Galina Karabanovich et al. JOURNAL OF MEDICINAL CHEMISTRY
- Crystal structure and stability of gyrase–fluoroquinolone cleaved complexes fromMycobacterium tuberculosis
- (2016) Tim R. Blower et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alteration in the Gut Microbiota Provokes Susceptibility to Tuberculosis
- (2016) Nargis Khan et al. Frontiers in Immunology
- Multi-drug delivery of tuberculosis drugs by π-back bonded gold nanoparticles with multiblock copolyesters
- (2016) Mani Gajendiran et al. Materials Research Express
- Isoniazid metabolism and hepatotoxicity
- (2016) Pengcheng Wang et al. Acta Pharmaceutica Sinica B
- Advances in nanotechnology-based carrier systems for targeted delivery of bioactive drug molecules with special emphasis on immunotherapy in drug resistant tuberculosis – a critical review
- (2015) Jagdeep Singh et al. DRUG DELIVERY
- Towards tuberculosis elimination: an action framework for low-incidence countries
- (2015) Knut Lönnroth et al. EUROPEAN RESPIRATORY JOURNAL
- Why healthcare workers are sick of TB
- (2015) Arne von Delft et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Nosocomial transmission of multidrug-resistant tuberculosis
- (2015) V. Crudu et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Accuracy of the Xpert® MTB/RIF assay for the diagnosis of extra-pulmonary tuberculosis in South Korea
- (2015) Y. W. Kim et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Mechanisms of drug resistance in Mycobacterium tuberculosis: update 2015
- (2015) Y. Zhang et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Identification of an anti-TB compound targeting the tyrosyl-tRNA synthetase
- (2015) Ningyu Zhu et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Bactericidal mode of action of bedaquiline
- (2015) K. Hards et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Rapid detection of Mycobacterium tuberculosis complex by real-time PCR in sputum samples and its use in the routine diagnosis in a reference laboratory
- (2015) Juliana Maira Watanabe Pinhata et al. JOURNAL OF MEDICAL MICROBIOLOGY
- WHO's new End TB Strategy
- (2015) Mukund Uplekar et al. LANCET
- Intrinsically disordered proteins in cellular signalling and regulation
- (2015) Peter E. Wright et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Costs to Health Services and the Patient of Treating Tuberculosis: A Systematic Literature Review
- (2015) Yoko V. Laurence et al. PHARMACOECONOMICS
- The diagnostic targeting of a carbohydrate virulence factor from M.Tuberculosis
- (2015) Conrad E. Chan et al. Scientific Reports
- Tuberculosis Treatment and Drug Regimens
- (2015) G. Sotgiu et al. Cold Spring Harbor Perspectives in Medicine
- Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM
- (2015) Anna Zhou et al. eLife
- Structure of the mycobacterial ATP synthase Fo rotor ring in complex with the anti-TB drug bedaquiline
- (2015) L. Preiss et al. Science Advances
- High cure rate with standardised short-course multidrug-resistant tuberculosis treatment in Niger: no relapses
- (2014) A. Piubello et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux
- (2014) Richard E Lee et al. NATURE MEDICINE
- P450-Mediated O-Demethylated Metabolite Is Responsible for Rat Hepatobiliary Toxicity of Pyridyltriazine-Containing PI3K Inhibitors
- (2014) Raju Subramanian et al. TOXICOLOGICAL SCIENCES
- Triosephosphate Isomerase Is Dispensable In Vitro yet Essential for Mycobacterium tuberculosis To Establish Infection
- (2014) C. Trujillo et al. mBio
- Mycobacterium tuberculosis Metabolism
- (2014) D. F. Warner Cold Spring Harbor Perspectives in Medicine
- Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing
- (2013) Yanjia J. Zhang et al. CELL
- Contact screening in tuberculosis: can we identify those with higher risk?: Table 1–
- (2013) Maria Aurora Mendes et al. EUROPEAN RESPIRATORY JOURNAL
- Potential antimicrobial agents for the treatment of multidrug-resistant tuberculosis
- (2013) N. Alsaad et al. EUROPEAN RESPIRATORY JOURNAL
- Fixed-dose combination antituberculosis therapy: a systematic review and meta-analysis
- (2013) Amr S. Albanna et al. EUROPEAN RESPIRATORY JOURNAL
- Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis
- (2013) M. McGrath et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis
- (2013) Regina Wilson et al. Nature Chemical Biology
- Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis
- (2013) Tulika Munshi et al. PLoS One
- Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
- (2013) F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macrophages in tuberculosis: friend or foe
- (2013) Evelyn Guirado et al. Seminars in Immunopathology
- New fluoroquinolones active against fluoroquinolones-resistant Mycobacterium tuberculosis strains
- (2013) Valentina Guerrini et al. TUBERCULOSIS
- Prevalence of Latent and Active Tuberculosis among Dairy Farm Workers Exposed to Cattle Infected by Mycobacterium bovis
- (2013) Pedro Torres-Gonzalez et al. PLoS Neglected Tropical Diseases
- Targeted Intracellular Delivery of Antituberculosis Drugs to Mycobacterium tuberculosis-Infected Macrophages via Functionalized Mesoporous Silica Nanoparticles
- (2012) Daniel L. Clemens et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antitubercular Activity of Disulfiram, an Antialcoholism Drug, against Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Isolates
- (2012) Yasuhiro Horita et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Functional and Genetic Characterization of the Tap Efflux Pump in Mycobacterium bovis BCG
- (2012) Santiago Ramón-García et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Efflux Pumps of Mycobacterium tuberculosis Play a Significant Role in Antituberculosis Activity of Potential Drug Candidates
- (2012) Meenakshi Balganesh et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Outwitting Evolution: Fighting Drug-Resistant TB, Malaria, and HIV
- (2012) Daniel E. Goldberg et al. CELL
- Totally Drug-Resistant and Extremely Drug-Resistant Tuberculosis: The Same Disease?
- (2012) G. B. Migliori et al. CLINICAL INFECTIOUS DISEASES
- Site of Extrapulmonary Tuberculosis is Associated with HIV Infection
- (2012) Ira L. Leeds et al. CLINICAL INFECTIOUS DISEASES
- Drug Susceptibility Testing for Optimizing Tuberculosis Treatment
- (2012) Sami O. Simons et al. CURRENT PHARMACEUTICAL DESIGN
- Contact investigation for tuberculosis: a systematic review and meta-analysis
- (2012) G. J. Fox et al. EUROPEAN RESPIRATORY JOURNAL
- Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis
- (2012) Vija Skripconoka et al. EUROPEAN RESPIRATORY JOURNAL
- Pre-XDR & XDR in MDR and Ofloxacin and Kanamycin resistance in non-MDR Mycobacterium tuberculosis isolates
- (2012) Amita Jain et al. TUBERCULOSIS
- The role of dendritic cells inMycobacterium tuberculosisinfection
- (2012) Adane Mihret Virulence
- Structural insights into RipC, a putative citrate lyase β subunit from aYersinia pestisvirulence operon
- (2011) Rodrigo Torres et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Treatment of Tuberculosis with Rifamycin-containing Regimens in Immune-deficient Mice
- (2011) Ming Zhang et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Mycobacterial PE/PPE Proteins at the Host-Pathogen Interface
- (2011) Samantha L. Sampson Clinical & Developmental Immunology
- Totally Drug-Resistant Tuberculosis in India
- (2011) Z. F. Udwadia et al. CLINICAL INFECTIOUS DISEASES
- A new evolutionary and pharmacokinetic–pharmacodynamic scenario for rapid emergence of resistance to single and multiple anti-tuberculosis drugs
- (2011) Jotam G Pasipanodya et al. CURRENT OPINION IN PHARMACOLOGY
- Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs
- (2011) P. E. Almeida Da Silva et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells To Program Cytotoxic Th1 Differentiation
- (2011) H. Z. Qui et al. JOURNAL OF IMMUNOLOGY
- Proteins with Complex Architecture as Potential Targets for Drug Design: A Case Study of Mycobacterium tuberculosis
- (2011) Bálint Mészáros et al. PLoS Computational Biology
- Treatment of drug-resistant tuberculosis
- (2011) Dick Menzies Infection and Drug Resistance
- Human Lung Immunity againstMycobacterium tuberculosis
- (2010) Stephan Schwander et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Rv1218c, an ABC Transporter of Mycobacterium tuberculosis with Implications in Drug Discovery
- (2010) M. Balganesh et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In Vitro and In Vivo Activities of LCB01-0371, a New Oxazolidinone
- (2010) J.-W. Jeong et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Biomarker-Assisted Dose Selection for Safety and Efficacy in Early Development of PNU-100480 for Tuberculosis
- (2010) Robert S. Wallis et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Can immune parameters be used as predictors to distinguish between pulmonary multidrug-resistant and drug-sensitive tuberculosis?
- (2010) Bayram Kiran et al. Archives of Medical Science
- Region of Difference 2 Contributes to Virulence ofMycobacterium tuberculosis
- (2010) Robert A. Kozak et al. INFECTION AND IMMUNITY
- Understanding Latent Tuberculosis: A Moving Target
- (2010) P. L. Lin et al. JOURNAL OF IMMUNOLOGY
- Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis
- (2010) Neel R Gandhi et al. LANCET
- Clinical Utility of a Commercial LAM-ELISA Assay for TB Diagnosis in HIV-Infected Patients Using Urine and Sputum Samples
- (2010) Keertan Dheda et al. PLoS One
- The Antipsychotic Thioridazine Shows Promising Therapeutic Activity in a Mouse Model of Multidrug-Resistant Tuberculosis
- (2010) Dick van Soolingen et al. PLoS One
- Epidemic Levels of Drug Resistant Tuberculosis (MDR and XDR-TB) in a High HIV Prevalence Setting in Khayelitsha, South Africa
- (2010) Helen S. Cox et al. PLoS One
- Protein targets for structure-based anti-Mycobacterium tuberculosis drug discovery
- (2010) Zhiyong Lou et al. Protein & Cell
- Cell-Mediated Immune Responses in Tuberculosis
- (2009) Andrea M. Cooper Annual Review of Immunology
- Emergence of New Forms of Totally Drug-Resistant Tuberculosis Bacilli
- (2009) Ali Akbar Velayati et al. CHEST
- Extensively drug-resistant tuberculosis
- (2009) Philip LoBue CURRENT OPINION IN INFECTIOUS DISEASES
- Signaling mechanisms of the Mycobacterium tuberculosis receptor Ser/Thr protein kinases
- (2009) Tom Alber CURRENT OPINION IN STRUCTURAL BIOLOGY
- Efflux-Mediated Drug Resistance in Bacteria
- (2009) Xian-Zhi Li et al. DRUGS
- The Pks13/FadD32 Crosstalk for the Biosynthesis of Mycolic Acids inMycobacterium tuberculosis
- (2009) Sabine Gavalda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Unraveling the potential of intrinsically disordered proteins as drug targets: application to Mycobacterium tuberculosis
- (2009) Meenakshi Anurag et al. Molecular BioSystems
- Synthetic EthR inhibitors boost antituberculous activity of ethionamide
- (2009) Nicolas Willand et al. NATURE MEDICINE
- The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
- (2009) Clifton E. Barry et al. NATURE REVIEWS MICROBIOLOGY
- Drivers of tuberculosis epidemics: The role of risk factors and social determinants
- (2009) Knut Lönnroth et al. SOCIAL SCIENCE & MEDICINE
- Inhibitors of FabI, an Enzyme Drug Target in the Bacterial Fatty Acid Biosynthesis Pathway
- (2008) Hao Lu et al. ACCOUNTS OF CHEMICAL RESEARCH
- In Vitro Activities of Linezolid against Clinical Isolates of Mycobacterium tuberculosis Complex Isolated in Taiwan over 10 Years
- (2008) T.-S. Huang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Alcohol use as a risk factor for tuberculosis – a systematic review
- (2008) Knut Lönnroth et al. BMC PUBLIC HEALTH
- Cavitary Pulmonary Disease
- (2008) L. B. Gadkowski et al. CLINICAL MICROBIOLOGY REVIEWS
- Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit∥
- (2008) Joseph A. Ippolito et al. JOURNAL OF MEDICINAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started