Perimortem Distribution of U-47700, Tramadol and Their Main Metabolites in Pigs Following Intravenous Administration

Time- and temperature-dependent postmortem concentration changes of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs

(2020) Nadine Schaefer et al.   ARCHIVES OF TOXICOLOGY

Pharmacodynamics and pharmacokinetics of the novel synthetic opioid, U-47700, in male rats

(2020) Michael T. Truver et al.   NEUROPHARMACOLOGY

Are pigs a suitable animal model for in vivo metabolism studies of new psychoactive substances? A comparison study using different in vitro/in vivo tools and U-47700 as model drug

(2020) Frederike Nordmeier et al.   TOXICOLOGY LETTERS

Postmortem concentrations of the synthetic opioid U-47700 in 26 fatalities associated with the drug

(2019) Helena Fels et al.   FORENSIC SCIENCE INTERNATIONAL

Distribution of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs

(2019) Nadine Schaefer et al.   ARCHIVES OF TOXICOLOGY

Distribution of synthetic opioids in postmortem blood, vitreous humor and brain

(2019) Rachel Chesser et al.   FORENSIC SCIENCE INTERNATIONAL

Mixed intoxication by the synthetic opioid U-47700 and the benzodiazepine flubromazepam with lethal outcome: Pharmacokinetic data

(2018) Katharina Koch et al.   Drug Testing and Analysis

Time-Dependent Postmortem Redistribution of Opioids in Blood and Alternative Matrices

(2018) Lana Brockbals et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review

(2018) Patil Armenian et al.   NEUROPHARMACOLOGY

First Case in Italy of Fatal Intoxication Involving the New Opioid U-47700

(2018) Enrico Gerace et al.   Frontiers in Pharmacology

Pharmacotoxicology of Non-fentanyl Derived New Synthetic Opioids

(2018) Renata Solimini et al.   Frontiers in Pharmacology

Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques?

(2018) Nadine Schaefer et al.   BIOCHEMICAL PHARMACOLOGY

Another fatal case related to the recreational abuse of U-47700

(2018) Nadine Strehmel et al.   Forensic Science Medicine and Pathology

Near-fatal Intoxication with the “New” Synthetic Opioid U-47700: The First Reported Case in the Czech Republic

(2018) Monika Židková et al.   JOURNAL OF FORENSIC SCIENCES

Case report: relevance of metabolite identification to detect new synthetic opioid intoxications illustrated by U-47700

(2018) Camille Richeval et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Postmortem concentration distribution in fatal cases involving the synthetic opioid U-47700

(2017) Marek Dziadosz et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

U-47700: A Not So New Opioid

(2017) Timothy P Rohrig et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Confirmation of Carfentanil, U-47700 and Other Synthetic Opioids in a Human Performance Case by LC–MS-MS

(2017) Joshua Seither et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

The first reported fatality associated with the synthetic opioid 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47700) and implications for forensic analysis

(2016) Simon P. Elliott et al.   Drug Testing and Analysis

A case of acute intoxication due to combined use of fentanyl and 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47700)

(2016) Vera Coopman et al.   FORENSIC SCIENCE INTERNATIONAL

Comparing fatal cases involving U-47700

(2016) Xiulu Ruan et al.   Forensic Science Medicine and Pathology

A Fatality Related to the Synthetic Opioid U-47700: Postmortem Concentration Distribution

(2016) Iain M. McIntyre et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Analysis of U-47700, a Novel Synthetic Opioid, in Human Urine by LC–MS–MS and LC–QToF

(2016) Steven W. Fleming et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Analysis of Novel Synthetic Opioids U-47700, U-50488 and Furanyl Fentanyl by LC–MS/MS in Postmortem Casework

(2016) Amanda L. A. Mohr et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Pigs in Toxicology

(2016) Kristi L. Helke et al.   TOXICOLOGIC PATHOLOGY

Pharmacokinetics of (synthetic) cannabinoids in pigs and their relevance for clinical and forensic toxicology

(2016) Nadine Schaefer et al.   TOXICOLOGY LETTERS

Simultaneous LC-MS/MS determination of JWH-210, RCS-4, ∆9-tetrahydrocannabinol, and their main metabolites in pig and human serum, whole blood, and urine for comparing pharmacokinetic data

(2015) Nadine Schaefer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Transport Characteristics of Tramadol in the Blood–Brain Barrier

(2014) Atsushi Kitamura et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Pharmacokinetics of tramadol and its major metabolite after intramuscular administration in piglets

(2014) C. Vullo et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Regulation of cerebral CYP2D alters tramadol metabolism in the brain: interactions of tramadol with propranolol and nicotine

(2014) Qiaoli Wang et al.   XENOBIOTICA

Xenobiotic Metabolizing Cytochrome P450 in Pig, a Promising Animal Model

(2013) Emanuela Puccinelli et al.   CURRENT DRUG METABOLISM

Postmortem Redistribution of Tramadol and O-Desmethyltramadol

(2013) I. Costa et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Distribution of metoprolol, tramadol, and midazolam in human autopsy material

(2011) R. Oertel et al.   JOURNAL OF CHROMATOGRAPHY A