Extracellular Vesicles Tune the Immune System in Renal Disease: A Focus on Systemic Lupus Erythematosus, Antiphospholipid Syndrome, Thrombotic Microangiopathy and ANCA-Vasculitis

Extracellular Vesicles and Renal Endothelial Cells: a Fatal Attraction in Hemolytic Uremic Syndrome

(2021) Elisa Varrone et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial cells response to neutrophil‐derived extracellular vesicles miRNAs in anti‐PR3 positive vasculitis

(2021) M. Surmiak et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Urinary Exosomal miRNA Expression Profile is Predictive of Clinical Response in Lupus Nephritis

(2020) Eloi Garcia-Vives et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plasma exosomal miRNAs involved in endothelial injury in microscopic polyangiitis patients

(2020) Yang Wang et al.   FASEB JOURNAL

Shiga Toxin-Bearing Microvesicles Exert a Cytotoxic Effect on Recipient Cells Only When the Cells Express the Toxin Receptor

(2020) Karl Johansson et al.   Frontiers in Cellular and Infection Microbiology

Characterization of Plasma-Derived Small Extracellular Vesicles Indicates Ongoing Endothelial and Platelet Activation in Patients with Thrombotic Antiphospholipid Syndrome

(2020) Ula Štok et al.   Cells

Mesenchymal Stem Cell Derived Extracellular Vesicles Ameliorate Kidney Injury in Aristolochic Acid Nephropathy

(2020) Sharad Kholia et al.   Frontiers in Cell and Developmental Biology

Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV)

(2020) M. Manojlovic et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Microvesicles in active lupus nephritis show Toll‐like receptor 9‐dependent co‐expression of galectin‐3 binding protein and double‐stranded DNA

(2020) N. S. Rasmussen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mass spectrometry-based proteomic exploration of the small urinary extracellular vesicles in ANCA-associated vasculitis in comparison with total urine

(2020) Petr Prikryl et al.   Journal of Proteomics

Role of Exosomes in the Regulation of T-cell Mediated Immune Responses and in Autoimmune Disease

(2019) Alberto Anel et al.   Cells

Platelets release proinflammatory microparticles in anti-neutrophil cytoplasmic antibody-associated vasculitis

(2019) Di Miao et al.   RHEUMATOLOGY

Microparticles in the blood of patients with SLE: Size, content of mitochondria and role in circulating immune complexes

(2019) Fariborz Mobarrez et al.   JOURNAL OF AUTOIMMUNITY

Microparticles expressing myeloperoxidase and complement C3a and C5a as markers of renal involvement in antineutrophil cytoplasmic antibody – associated vasculitis

(2019) Aleksandra Antovic et al.   JOURNAL OF RHEUMATOLOGY

An Exosomal Urinary miRNA Signature for Early Diagnosis of Renal Fibrosis in Lupus Nephritis

(2019) Solé et al.   Cells

Urinary podocyte microparticles are associated with disease activity and renal injury in systemic lupus erythematosus

(2019) Jian Lu et al.   BMC Nephrology

LTB4 and 5-oxo-ETE from extracellular vesicles stimulate neutrophils in granulomatosis with polyangiitis

(2019) Marcin Surmiak et al.   JOURNAL OF LIPID RESEARCH

Urinary Extracellular Vesicles Carrying Klotho Improve the Recovery of Renal Function in an Acute Tubular Injury Model

(2019) Cristina Grange et al.   MOLECULAR THERAPY

Circulating microparticles in pregnant patients with primary anti-phospholipid syndrome: an exploratory study

(2018) E Campello et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Potential Involvement of Platelet-Derived Microparticles and Microparticles Forming Immune Complexes during Monocyte Activation in Patients with Systemic Lupus Erythematosus

(2018) Catalina Burbano et al.   Frontiers in Immunology

HMGB1+ microparticles present in urine are hallmarks of nephritis in patients with systemic lupus erythematosus

(2018) Catalina Burbano et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MicroRNA expression profile of urinary exosomes in Type IV lupus nephritis complicated by cellular crescent

(2018) Yi Li et al.   Journal of Biological Research-Thessaloniki

Circulating microparticle subpopulations in systemic lupus erythematosus are affected by disease activity

(2017) Patricia López et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

HMGB1 contributes to glomerular endothelial cell injury in ANCA-associated vasculitis through enhancing endothelium-neutrophil interactions

(2017) Chen Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Perfusion of isolated rat kidney with Mesenchymal Stromal Cells/Extracellular Vesicles prevents ischaemic injury

(2017) Marilena Gregorini et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Altered β2 -glycoprotein I expression on microparticles in the presence of antiphospholipid antibodies

(2017) F. Mobarrez et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Microvesicle transfer of kinin B1-receptors is a novel inflammatory mechanism in vasculitis

(2017) Robin Kahn et al.   KIDNEY INTERNATIONAL

Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases

(2017) Anne-lie Ståhl et al.   PEDIATRIC NEPHROLOGY

Extracellular Vesicles in the Antiphospholipid Syndrome

(2017) Ravi Alluri et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

The effects of glomerular and tubular renal progenitors and derived extracellular vesicles on recovery from acute kidney injury

(2017) Andrea Ranghino et al.   Stem Cell Research & Therapy

Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis

(2017) Nils Rother et al.   Frontiers in Immunology

Profiling analysis of circulating microRNA in peripheral blood of patients with class IV lupus nephritis

(2017) Elkin Navarro-Quiroz et al.   PLoS One

Role of extracellular vesicles in autoimmune diseases

(2016) Delphine Turpin et al.   AUTOIMMUNITY REVIEWS

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity

(2016) Vanja Sisirak et al.   CELL

Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells

(2016) W. Oosthuyzen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activated Stat5 trafficking Via Endothelial Cell-derived Extracellular Vesicles Controls IL-3 Pro-angiogenic Paracrine Action

(2016) Giusy Lombardo et al.   Scientific Reports

Microparticles in the blood of patients with systemic lupus erythematosus (SLE): phenotypic characterization and clinical associations

(2016) Fariborz Mobarrez et al.   Scientific Reports

Circulating Apoptotic Microparticles in Systemic Lupus Erythematosus Patients Drive the Activation of Dendritic Cell Subsets and Prime Neutrophils for NETosis

(2016) Jürgen Dieker et al.   Arthritis & Rheumatology

Mesenchymal Stromal Cells Epithelial Transition Induced by Renal Tubular Cells-Derived Extracellular Vesicles

(2016) Giulia Chiabotto et al.   PLoS One

Exosomal GAPDH from Proximal Tubule Cells Regulate ENaC Activity

(2016) Kishore Kumar Jella et al.   PLoS One

Shiga Toxin–Induced Complement-Mediated Hemolysis and Release of Complement-Coated Red Blood Cell–Derived Microvesicles in Hemolytic Uremic Syndrome

(2015) Ida Arvidsson et al.   JOURNAL OF IMMUNOLOGY

Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis

(2015) C T Nielsen et al.   LUPUS

miR-29c in urinary exosomes as predictor of early renal fibrosis in lupus nephritis

(2015) Cristina Solé et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Increased Urinary Exosomal MicroRNAs in Patients with Systemic Lupus Erythematosus

(2015) Javier Perez-Hernandez et al.   PLoS One

Endothelial and platelet microparticles in patients with antiphospholipid antibodies

(2015) K.A. Breen et al.   THROMBOSIS RESEARCH

A Novel Mechanism of Bacterial Toxin Transfer within Host Blood Cell-Derived Microvesicles

(2015) Anne-lie Ståhl et al.   PLoS Pathogens

Promotion of Hypercoagulability in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis by C5a-Induced Tissue Factor-Expressing Microparticles and Neutrophil Extracellular Traps

(2015) Yi-Min Huang et al.   Arthritis & Rheumatology

Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients

(2014) R Cervera et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil-derived microparticles induce myeloperoxidase-mediated damage of vascular endothelial cells

(2014) Thassila Pitanga et al.   BMC CELL BIOLOGY

Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells

(2014) John J. Gildea et al.   CLINICAL BIOCHEMISTRY

Human Urinary Exosomes as Innate Immune Effectors

(2014) T. F. Hiemstra et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Emerging role of extracellular vesicles in inflammatory diseases

(2014) Edit I. Buzas et al.   Nature Reviews Rheumatology

Immunotherapeutic Potential of Extracellular Vesicles

(2014) Bin Zhang et al.   Frontiers in Immunology

Complement Activation Associated with ADAMTS13 Deficiency in Human and Murine Thrombotic Microangiopathy

(2013) R. Tati et al.   JOURNAL OF IMMUNOLOGY

Subfractionation, characterization, and in-depth proteomic analysis of glomerular membrane vesicles in human urine

(2013) Marie C. Hogan et al.   KIDNEY INTERNATIONAL

Oxidative stress in the pathology and treatment of systemic lupus erythematosus

(2013) Andras Perl   Nature Reviews Rheumatology

Plasma Microparticle Tissue Factor Activity in Patients With Antiphospholipid Antibodies With and Without Clinical Complications

(2013) Rose Willemze et al.   THROMBOSIS RESEARCH

2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

(2012) J. C. Jennette et al.   ARTHRITIS AND RHEUMATISM

The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes

(2012) Nathalie Cloutier et al.   EMBO Molecular Medicine

TGF- 1-Containing Exosomes from Injured Epithelial Cells Activate Fibroblasts to Initiate Tissue Regenerative Responses and Fibrosis

(2012) F. T. Borges et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody–associated vasculitis

(2012) Shen-Ju Gou et al.   KIDNEY INTERNATIONAL

Studies of microparticles in patients with the antiphospholipid syndrome (APS)

(2012) A Vikerfors et al.   LUPUS

Therapeutic potential of mesenchymal stem cell-derived microvesicles

(2012) L. Biancone et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis

(2012) Bevra H. Hahn et al.   ARTHRITIS CARE & RESEARCH

Pathogenesis of ANCA-Associated Vasculitis

(2012) Rodrigo Cartin-Ceba et al.   Current Rheumatology Reports

Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands

(2012) Stephan Munich et al.   OncoImmunology

Distinct features of circulating microparticles and their relationship to clinical manifestations in systemic lupus erythematosus

(2011) Christoffer T. Nielsen et al.   ARTHRITIS AND RHEUMATISM

Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome

(2011) A.-l. Stahl et al.   BLOOD

Microparticles in Hemostasis and Thrombosis

(2011) A. Phillip Owens et al.   CIRCULATION RESEARCH

Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus

(2011) Anirudh J. Ullal et al.   JOURNAL OF AUTOIMMUNITY

Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells

(2011) Jonathan M. Street et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exosomes and the kidney: prospects for diagnosis and therapy of renal diseases

(2011) Bas W.M. van Balkom et al.   KIDNEY INTERNATIONAL

Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus

(2011) Sulaiman M Al-Mayouf et al.   NATURE GENETICS

Neutrophils in the pathogenesis and manifestations of SLE

(2011) Mariana J. Kaplan   Nature Reviews Rheumatology

Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy

(2011) Pyong-Gon Moon et al.   PROTEOMICS

Caucasian-specific allele in non-synonymous single nucleotide polymorphisms of the gene encoding deoxyribonuclease I-like 3, potentially relevant to autoimmunity, produces an inactive enzyme

(2009) Misuzu Ueki et al.   CLINICA CHIMICA ACTA

Shiga Toxin and Lipopolysaccharide Induce Platelet-Leukocyte Aggregates and Tissue Factor Release, a Thrombotic Mechanism in Hemolytic Uremic Syndrome

(2009) Anne-lie Ståhl et al.   PLoS One

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

(2008) P. A. Gonzales et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lymphocytic microparticles inhibit angiogenesis by stimulating oxidative stress and negatively regulating VEGF-induced pathways

(2007) Chun Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY