DNA Methylation Patterns Correlate with the Expression of SCNN1A, SCNN1B, and SCNN1G (Epithelial Sodium Channel, ENaC) Genes

CpG and non-CpG Presenilin1 methylation pattern in course of neurodevelopment and neurodegeneration is associated with gene expression in human and murine brain

(2020) Noemi Monti et al.   Epigenetics

A DNA methylation signature to improve survival prediction of gastric cancer

(2020) Yaojun Peng et al.   Clinical Epigenetics

Ursodeoxycholic acid inhibits ENaC and Na/K pump activity to restore airway surface liquid height in cystic fibrosis bronchial epithelial cells

(2019) Magdalena S. Mroz et al.   STEROIDS

MiR-146a is over-expressed and controls IL-6 production in cystic fibrosis macrophages

(2019) Francesco R. Luly et al.   Scientific Reports

Active Demethylation of Non-CpG Moieties in Animals: A Neglected Research Area

(2019) Marco Lucarelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The epithelial sodium channel (ENaC) as a therapeutic target for cystic fibrosis lung disease

(2018) Patrick J. Moore et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Assembly and Functional Analysis of an S/MAR Based Episome with the Cystic Fibrosis Transmembrane Conductance Regulator Gene

(2018) Davide De Rocco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ion channels as targets to treat cystic fibrosis lung disease

(2018) S. Lorraine Martin et al.   Journal of Cystic Fibrosis

The epithelial sodium channel (ENaC) as a therapeutic target for cystic fibrosis

(2018) Ren-Jay Shei et al.   CURRENT OPINION IN PHARMACOLOGY

Inhaled ENaC antisense oligonucleotide ameliorates cystic fibrosis-like lung disease in mice

(2017) Jeff R. Crosby et al.   Journal of Cystic Fibrosis

A New Targeted CFTR Mutation Panel Based on Next-Generation Sequencing Technology

(2017) Marco Lucarelli et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis

(2017) Maria D. I. Manunta et al.   Scientific Reports

Epithelial sodium channel (ENaC) family: Phylogeny, structure–function, tissue distribution, and associated inherited diseases

(2016) Israel Hanukoglu et al.   GENE

Epithelial Sodium Channels in Pulmonary Epithelial Progenitor and Stem Cells

(2016) Yang Liu et al.   International Journal of Biological Sciences

Genotype–phenotype correlation and functional studies in patients with cystic fibrosis bearing CFTR complex alleles

(2016) Vito Terlizzi et al.   JOURNAL OF MEDICAL GENETICS

The Impact on Genetic Testing of Mutational Patterns of CFTR Gene in Different Clinical Macrocategories of Cystic Fibrosis

(2016) Marco Lucarelli et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Association of SCNN1B promoter methylation with essential hypertension

(2016) Qilong Zhong et al.   Molecular Medicine Reports

Targeting ion channels in cystic fibrosis

(2015) Marcus A. Mall et al.   Journal of Cystic Fibrosis

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(2015) Marco Lucarelli et al.   MOLECULAR MEDICINE

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

(2015) Harriet Corvol et al.   Nature Communications

Cystic fibrosis genetics: from molecular understanding to clinical application

(2014) Garry R. Cutting   NATURE REVIEWS GENETICS

Lentiviral small hairpin RNA delivery reduces apical sodium channel activity in differentiated human airway epithelial cells

(2012) Jamil Aarbiou et al.   JOURNAL OF GENE MEDICINE

The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease

(2011) Zhe Zhou et al.   Journal of Cystic Fibrosis

Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells

(2010) Ronald C. Rubenstein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Modifier genes in Mendelian disorders: the example of cystic fibrosis

(2010) Garry R. Cutting   Annals of the New York Academy of Sciences

Regulation of the epithelial sodium channel (ENaC) by membrane trafficking

(2010) Michael B. Butterworth   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Early demethylation of non-CpG, CpC-rich, elements in the myogenin 5’-flanking region

(2010) Andrea Fuso et al.   CELL CYCLE

CFTR expression and activity from the human CFTR locus in BAC vectors, with regulatory regions, isolated by a single-step procedure

(2010) C Auriche et al.   GENE THERAPY

A new complex allele of the CFTR gene partially explains the variable phenotype of the L997F mutation

(2010) Marco Lucarelli et al.   GENETICS IN MEDICINE

The Cystic Fibrosis Transmembrane Conductance Regulator Impedes Proteolytic Stimulation of the Epithelial Na+Channel

(2010) Martina Gentzsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Characterization of a Partial Loss-of-Function Mutation of the Epithelial Sodium Channel (ENaC) Associated with Atypical Cystic Fibrosis

(2009) Regina Huber et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease

(2009) Abul Kalam Azad et al.   HUMAN MUTATION

Camostat Attenuates Airway Epithelial Sodium Channel Function in Vivo through the Inhibition of a Channel-Activating Protease

(2009) K. Coote et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Preventive but Not Late Amiloride Therapy Reduces Morbidity and Mortality of Lung Disease in βENaC-overexpressing Mice

(2008) Zhe Zhou et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Genetic Analysis of Rwandan Patients With Cystic Fibrosis-Like Symptoms

(2008) Léon Mutesa et al.   CHEST

Upregulated expression of ENaC in human CF nasal epithelium

(2007) Nadine Bangel et al.   Journal of Cystic Fibrosis