MiR-146a is over-expressed and controls IL-6 production in cystic fibrosis macrophages

Cystic Fibrosis Plasma Blunts the Immune Response to Bacterial Infection

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MicroRNAs as Molecular Switches in Macrophage Activation

(2019) Graziella Curtale et al.   Frontiers in Immunology

Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa

(2018) Roxanna Barnaby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Small RNA and transcriptome sequencing reveal the role of miR-199a-3p in inflammatory processes in cystic fibrosis airways

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Phagocytosis depends on TRPV2-mediated calcium influx and requires TRPV2 in lipids rafts: alteration in macrophages from patients with cystic fibrosis

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Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function

(2018) Shuzhong Zhang et al.   Scientific Reports

CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosis

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The impact of impaired macrophage functions in cystic fibrosis disease progression

(2017) Manuella Lévêque et al.   Journal of Cystic Fibrosis

miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions

(2017) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses

(2017) Mati Mann et al.   Nature Communications

Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages

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miR-146a, miR-155, miR-370, and miR-708 Are CFTR-Dependent, Predicted FOXO1 Regulators and Change at Onset of CFRDs

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Cystic Fibrosis Lung Immunity: The Role of the Macrophage

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Origins of Cystic Fibrosis Lung Disease

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Origins of Cystic Fibrosis Lung Disease

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The Functions of MicroRNAs: mRNA Decay and Translational Repression

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Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation

(2015) Ping-xia Zhang et al.   Nature Communications

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

(2015) Margaret Alexander et al.   Nature Communications

Optimal Complement-Mediated Phagocytosis ofPseudomonas aeruginosaby Monocytes Is Cystic Fibrosis Transmembrane Conductance Regulator–Dependent

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Post-Transcriptional Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Expression and Function by MicroRNAs

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Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by MicroRNA-145, -223, and -494 Is Altered in  F508 Cystic Fibrosis Airway Epithelium

(2013) I. K. Oglesby et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-146a Feedback Suppresses T Cell Immune Function by Targeting Stat1 in Patients with Chronic Hepatitis B

(2013) S. Wang et al.   JOURNAL OF IMMUNOLOGY

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(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Reactive-Oxygen-Species-Mediated P. aeruginosa Killing Is Functional in Human Cystic Fibrosis Macrophages

(2013) Noemi Cifani et al.   PLoS One

Impaired Functions of Macrophage from Cystic Fibrosis Patients: CD11b, TLR-5 Decrease and sCD14, Inflammatory Cytokines Increase

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Exaggerated inflammatory responses mediated by Burkholderia cenocepacia in human macrophages derived from Cystic fibrosis patients

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A Novel Regulator of Macrophage Activation

(2012) Guoqing Zhuang et al.   CIRCULATION

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(2012) Ben Langmead et al.   NATURE METHODS

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(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients

(2012) Kaleb M Pauley et al.   ARTHRITIS RESEARCH & THERAPY

miR-511-3p Modulates Genetic Programs of Tumor-Associated Macrophages

(2012) Mario Leonardo Squadrito et al.   Cell Reports

Altered miR-146a expression in Sjögren's syndrome and its functional role in innate immunity

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Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis

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Dysfunctional CFTR Alters the Bactericidal Activity of Human Macrophages against Pseudomonas aeruginosa

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The Interleukin 13 (IL-13) Pathway in Human Macrophages Is Modulated by MicroRNA-155 via Direct Targeting of Interleukin 13 Receptor α1 (IL13Rα1)

(2010) Rocio T. Martinez-Nunez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-126 Is Downregulated in Cystic Fibrosis Airway Epithelial Cells and Regulates TOM1 Expression

(2010) Irene K. Oglesby et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

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A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

(2008) Catherine Labbaye et al.   NATURE CELL BIOLOGY