Modifier genes in Mendelian disorders: the example of cystic fibrosis

Update on cystic fibrosis-related diabetes

(2010) Arlene A Stecenko et al.   CURRENT OPINION IN PULMONARY MEDICINE

Use of a modeling framework to evaluate the effect of a modifier gene (MBL2) on variation in cystic fibrosis

(2010) Kathryn E McDougal et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis

(2010) Xingshen Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

(2010) D. A. Stoltz et al.   Science Translational Medicine

Cystic Fibrosis-Related Diabetes: Current Trends in Prevalence, Incidence, and Mortality

(2009) A. Moran et al.   DIABETES CARE

A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis

(2009) S. M. Blackman et al.   DIABETOLOGIA

Modifier gene study of meconium ileus in cystic fibrosis: statistical considerations and gene mapping results

(2009) Ruslan Dorfman et al.   HUMAN GENETICS

Genetic Modifiers of Liver Disease in Cystic Fibrosis

(2009) Jaclyn R. Bartlett   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Associação entre os polimorfismos dos genes MBL2, TGF-β1 e CD14 com a gravidade da doença pulmonar na fibrose cística

(2009) Elisangela Jacinto de Faria et al.   Jornal Brasileiro de Pneumologia

Genetic Modifiers Play a Substantial Role in Diabetes Complicating Cystic Fibrosis

(2009) Scott M. Blackman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease

(2009) YuanYuan Gu et al.   NATURE

EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates, and cystic fibrosis pulmonary disease severity

(2009) Rebecca Darrah et al.   PHYSIOLOGICAL GENOMICS

Update on gene modifiers in cystic fibrosis

(2008) Joseph M Collaco et al.   CURRENT OPINION IN PULMONARY MEDICINE

Modulation of cystic fibrosis lung disease by variants in interleukin-8

(2008) A D Hillian et al.   GENES AND IMMUNITY

Interaction between a novel TGFB1 haplotype and CFTR genotype is associated with improved lung function in cystic fibrosis

(2008) Lindsay A. Bremer et al.   HUMAN MOLECULAR GENETICS

Interactions Between Secondhand Smoke and Genes That Affect Cystic Fibrosis Lung Disease

(2008) J. Michael Collaco et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Glucagon-like Peptide-1 Activation of TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell Proliferation

(2008) Zhengyu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact ofTCF7L2rs7903146 on Insulin Secretion and Action in Young and Elderly Danish Twins

(2008) Lise Wegner et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetic variations in inflammatory mediators influence lung disease progression in cystic fibrosis

(2008) Harriet Corvol et al.   PEDIATRIC PULMONOLOGY