The Effects of Muscle Cell Aging on Myogenesis

Optimizing mechanical stretching protocols for hypertrophic and anti-apoptotic responses in cardiomyocyte-like H9C2 cells

(2021) Evangelos Zevolis et al.   MOLECULAR BIOLOGY REPORTS

Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice

(2020) Yusheng Cai et al.   CELL RESEARCH

Age and prior exercise in vivo determine the subsequent in vitro molecular profile of myoblasts and non-myogenic cells derived from human skeletal muscle

(2019) Cecilie J.L. Bechshøft et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effects of IGF‐1 isoforms on muscle growth and sarcopenia

(2019) Francesca Ascenzi et al.   AGING CELL

Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation

(2019) Lance T. Denes et al.   Skeletal Muscle

CRISPR‐Cas9–induced IGF1 gene activation as a tool for enhancing muscle differentiation via multiple isoform expression

(2019) Matthew J. Roberston et al.   FASEB JOURNAL

In vitro exercise model using contractile human and mouse hybrid myotubes

(2019) Weijian Chen et al.   Scientific Reports

Myogenic regulatory factors: The orchestrators of myogenesis after 30 years of discovery

(2018) Hasan A Asfour et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Regulation of cellular senescence via the FOXO4-p53 axis

(2018) Benjamin Bourgeois et al.   FEBS LETTERS

The physiopathologic role of oxidative stress in skeletal muscle

(2018) Bianca Maria Scicchitano et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Stress, cell senescence and organismal ageing

(2018) João Pedro de Magalhães et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Age- and Tissue-Specific Expression of Senescence Biomarkers in Mice

(2018) Adam D. Hudgins et al.   Frontiers in Genetics

Biological activity of the e domain of the IGF-1Ec as addressed by synthetic peptides

(2018) George Vassilakos et al.   Hormones-International Journal of Endocrinology and Metabolism

In vitro experimental models for examining the skeletal muscle cell biology of exercise: the possibilities, challenges and future developments

(2018) Steven Carter et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Identification of the IGF-1 processing product human Ec/rodent Eb peptide in various tissues: Evidence for its differential regulation after exercise-induced muscle damage in humans

(2017) George Vassilakos et al.   GROWTH HORMONE & IGF RESEARCH

The myogenic regulatory factors, determinants of muscle development, cell identity and regeneration

(2017) J. Manuel Hernández-Hernández et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Novel p53 target geneFUCA1encodes a fucosidase and regulates growth and survival of cancer cells

(2016) Issei Ezawa et al.   CANCER SCIENCE

The human Ec peptide: the active core of a progression growth factor with species-specific mode of action

(2016) Efstathia Papageorgiou et al.   Hormones-International Journal of Endocrinology and Metabolism

Replicatively senescent cells are arrested in G1 and G2 phases

(2016) Zhiyong Mao et al.   Aging-US

Masticatory muscles of mouse do not undergo atrophy in space

(2015) Anastassios Philippou et al.   FASEB JOURNAL

Role of Inflammation in Muscle Homeostasis and Myogenesis

(2015) Domiziana Costamagna et al.   MEDIATORS OF INFLAMMATION

Muscle-specific E3 ubiquitin ligases are involved in muscle atrophy of cancer cachexia: An in vitro and in vivo study

(2015) LEI YUAN et al.   ONCOLOGY REPORTS

The ins and outs of muscle stem cell aging

(2015) Andrew S. Brack et al.   Skeletal Muscle

Aberrant DNA Damage Response Pathways May Predict the Outcome of Platinum Chemotherapy in Ovarian Cancer

(2015) Dimitra T. Stefanou et al.   PLoS One

Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1

(2014) Sue C. Bodine et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Modelling the onset of senescence at the G1/S cell cycle checkpoint

(2014) José CM Mombach et al.   BMC GENOMICS

p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress

(2014) Z J P Yang et al.   CELL DEATH AND DIFFERENTIATION

Optimizing IGF-I for skeletal muscle therapeutics

(2014) Anastassios Philippou et al.   GROWTH HORMONE & IGF RESEARCH

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Insulin and LiCl Synergistically Rescue Myogenic Differentiation of FoxO1 Over-Expressed Myoblasts

(2014) Yi Ju Wu et al.   PLoS One

Absence of γ-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle

(2014) Catherine Moorwood et al.   Skeletal Muscle

Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

(2013) F. Demontis et al.   Disease Models & Mechanisms

The pro-Forms of Insulin-Like Growth Factor I (IGF-I) Are Predominant in Skeletal Muscle and Alter IGF-I Receptor Activation

(2013) Julia Durzyńska et al.   ENDOCRINOLOGY

Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials

(2013) Emanuele Marzetti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Evidence for the Possible Biological Significance of the igf-1 Gene Alternative Splicing in Prostate Cancer

(2013) Anastassios Philippou et al.   Frontiers in Endocrinology

Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF production

(2012) Elisabeth R. Barton et al.   FASEB JOURNAL

Perspective: Protein and Exercise for Frailty and Sarcopenia: Still Learning

(2012) Alfonso J. Cruz-Jentoft   Journal of the American Medical Directors Association

Myoblast models of skeletal muscle hypertrophy and atrophy

(2011) Adam P Sharples et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Reduction of myoblast differentiation following multiple population doublings in mouse C2C12 cells: A model to investigate ageing?

(2011) Adam P. Sharples et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Unknown

(2011) Dimitrios Milingos et al.   MOLECULAR MEDICINE

Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt

(2009) Michael R. Morissette et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

(2009) Anne Ulrike Trendelenburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Selective activation of PPARγ in skeletal muscle induces endogenous production of adiponectin and protects mice from diet-induced insulin resistance

(2009) Rajesh H. Amin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Identification of MAFbx as a myogenin-engaged F-box protein in SCF ubiquitin ligase

(2009) Misako Jogo et al.   FEBS LETTERS

Unknown

(2009) Anastasia Stavropoulou et al.   MOLECULAR MEDICINE

Distinct mechanisms act in concert to mediate cell cycle arrest

(2009) Jared E. Toettcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atrophy and programmed cell death of skeletal muscle

(2008) L M Schwartz   CELL DEATH AND DIFFERENTIATION

Skeletal muscle proteolysis in aging

(2008) Lydie Combaret et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE